Transcriptional downregulation of miR‐127‐3p by CTCF promotes prostate cancer bone metastasis by targeting PSMB5
Sign Up to like & getrecommendations! Published in 2019 at "FEBS Letters"
DOI: 10.1002/1873-3468.13624
Abstract: Prostate cancer (PCa) is one of the most common cancers in males and particularly tends to metastasize to bone. Currently, metastatic bone disease is incurable, and new therapies need to be developed. Our study aims… read more here.
Keywords: ctcf; bone; pca; bone metastasis ... See more keywords
hsa_circ_0000285 facilitates thyroid cancer progression by regulating miR-127-5p/CDH2.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of clinical laboratory analysis"
DOI: 10.1002/jcla.24421
Abstract: Thyroid cancer (THCA) is a leading endocrine cancer and becomes the fifth most commonly diagnosed malignancy in females. It is confirmed that circular RNAs (circRNAs) perform regulatory potencies in the pathological progress of THCA. Our… read more here.
Keywords: circ 0000285; thca; mir 127; hsa circ ... See more keywords
Identification of endogenous microRNA references in porcine serum for quantitative real-time PCR normalization
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Biology Reports"
DOI: 10.1007/s11033-018-4242-4
Abstract: MicroRNAs (miRNAs) are evolutionarily conserved small non-coding RNAs that regulate the expression of genes, and they affect important biological and physiological states. Circulating miRNAs in blood are useful markers of metabolism and economic traits. Expression… read more here.
Keywords: real time; quantitative real; mir; reference ... See more keywords
MicroRNA-127 Promotes Anti-microbial Host Defense through Restricting A20-Mediated De-ubiquitination of STAT3
Sign Up to like & getrecommendations! Published in 2019 at "iScience"
DOI: 10.1016/j.isci.2019.100763
Abstract: Summary The increasing rising of multiple drug-resistant Staphylococcus aureus has become a major public health concern, underscoring a pressing need for developing therapies essentially based on the understanding of host defensive mechanism. In the present… read more here.
Keywords: mir 127; anti microbial; ubiquitination stat3; host ... See more keywords
Extracellular vesicle-mediated delivery of miR-127-3p inhibits the proliferation and invasion of choriocarcinoma cells by targeting ITGA6.
Sign Up to like & getrecommendations! Published in 2022 at "Experimental cell research"
DOI: 10.1016/j.yexcr.2022.113098
Abstract: BACKGROUND Choriocarcinoma (CC) is a highly aggressive malignant tumor that mostly occurs in women of childbearing age. Chemotherapy is the main treatment for CC, but it has side effects and causes drug resistance, which can… read more here.
Keywords: choriocarcinoma; targeting itga6; proliferation invasion; cells targeting ... See more keywords
Is MicroRNA-127 a Novel Biomarker for Acute Pancreatitis with Lung Injury?
Sign Up to like & getrecommendations! Published in 2017 at "Disease Markers"
DOI: 10.1155/2017/1204295
Abstract: Background and Aims The aim of this study was to determine the expression of microRNA-127 (miR-127) in both rat models and patients of acute pancreatitis (AP) with lung injury (LI). Methods Rats were administrated with… read more here.
Keywords: acute pancreatitis; pancreatitis lung; lung injury; mir 127 ... See more keywords
Astragalus polysaccharide alleviates LPS-induced inflammation injury by regulating miR-127 in H9c2 cardiomyoblasts
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Immunopathology and Pharmacology"
DOI: 10.1177/2058738418759180
Abstract: Astragalus polysaccharide (APS) has been widely reported to play an important role in inflammatory response. In this study, we aimed to explore the effects and underlying mechanisms of APS on lipopolysaccharide (LPS)-induced inflammation injury in… read more here.
Keywords: h9c2 cells; lps induced; induced inflammation; inflammation injury ... See more keywords
LncRNA FOXD3-AS1 promoted chemo-resistance of NSCLC cells via directly acting on miR-127-3p/MDM2 axis
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Cell International"
DOI: 10.1186/s12935-020-01402-9
Abstract: Background This study aims to investigate the mechanism underlying the high level of long non-coding RNA FOXD3-AS1 in cisplatin-resistant NSCLC cells. Methods Cisplatin-resistant cells were generated from A549 cells. CCK-8 were used to evaluate cell… read more here.
Keywords: foxd3 as1; mir 127; mdm2; nsclc cells ... See more keywords
Downregulation of Renal Hsa-miR-127-3p Contributes to the Overactivation of Type I Interferon Signaling Pathway in the Kidney of Lupus Nephritis
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.747616
Abstract: MicroRNAs are involved in the pathogenesis of systemic lupus erythematosus (SLE) and dysregulated in the kidneys of lupus nephritis (LN) patients, but their pathogenic roles in LN are largely unknown. Janus Kinase 1 (JAK1) mediates… read more here.
Keywords: hsa mir; ifn signaling; signaling pathway; mir 127 ... See more keywords
MicroRNA-127 promotes anti-microbial ability in porcine alveolar macrophages via S1PR3/TLR signaling pathway
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Veterinary Science"
DOI: 10.4142/jvs.22110
Abstract: Background As Actinobacillus pleuropneumonniae (APP) infection causes considerable losses in the pig industry, there is a growing need to develop effective therapeutic interventions that leverage host immune defense mechanisms to combat these pathogens. Objectives To… read more here.
Keywords: s1pr3; signaling pathway; mir 127; app ... See more keywords
Expression Levels of miR-127-3p and miR-144-3p in Gastric Cancer and their Relationships with Clinicopathological Parameters.
Sign Up to like & getrecommendations! Published in 2020 at "Clinical laboratory"
DOI: 10.7754/clin.lab.2020.200417
Abstract: BACKGROUND Previous studies demonstrated the critical role of miRNAs in carcinogenesis. Aberrant expression of miR-127-3p and miR-144-3p have been revealed in several types of cancers. METHODS Expression levels of miR-127-3p and miR-144-3p were detected in… read more here.
Keywords: 127 mir; expression levels; mir; mir 144 ... See more keywords