MiRNA‐1271‐5p regulates osteogenic differentiation of human bone marrow‐derived mesenchymal stem cells by targeting forkhead box O1 (FOXO1)
Sign Up to like & getrecommendations! Published in 2021 at "Cell Biology International"
DOI: 10.1002/cbin.11585
Abstract: Forkhead box O1 (FOXO1) is a key regulator of osteogenesis. The aim of this study was to identify the mechanisms of microRNAs (miRNAs) targeting FOXO1 in osteogenic differentiation of human bone marrow mesenchymal stem cells… read more here.
Keywords: foxo1; bone; expression; osteogenic differentiation ... See more keywords
FOXC2-induced circCASK aggravates colorectal cancer progression by upregulating SIX1 expression.
Sign Up to like & getrecommendations! Published in 2023 at "IUBMB life"
DOI: 10.1002/iub.2718
Abstract: Colorectal cancer (CRC) ranks as the most common gastrointestinal solid carcinoma globally. Substantial evidence has established a pivotal role for circular RNAs (circRNAs) in CRC progression. In this study, differentially expressed circRNAs were analyzed based… read more here.
Keywords: mir 1271; progression; induced circcask; expression ... See more keywords
MicroRNA‐1271 suppresses the proliferation and invasion of colorectal cancer cells by regulating metadherin/Wnt signaling
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.22028
Abstract: Recent studies have reported an important role for microRNA‐1271 (miR‐1271) in tumorigenesis. However, the role of miR‐1271 in colorectal cancer remains unknown. Here, we found that miR‐1271 was significantly decreased in colorectal cancer tissues and… read more here.
Keywords: cancer; colorectal cancer; mir 1271; cancer cells ... See more keywords
Circ_0039569 contributes to the paclitaxel resistance of endometrial cancer via targeting miR-1271-5p/PHF6 pathway
Sign Up to like & getrecommendations! Published in 2022 at "Anti-Cancer Drugs"
DOI: 10.1097/cad.0000000000001377
Abstract: Circular RNA (circRNA) has been confirmed to be involved in the chemoresistance process of cancers. However, whether circ_0039569 mediates the chemoresistance of endometrial cancer (EC) remains unclear. Quantitative real-time PCR was performed to analyze circ_0039569,… read more here.
Keywords: mir 1271; ptx sensitivity; 1271 phf6; circ 0039569 ... See more keywords
miR-1271 inhibits ERα expression and confers letrozole resistance in breast cancer
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DOI: 10.18632/oncotarget.22359
Abstract: Attenuation of estrogen receptor α (ERα) expression via unknown mechanism(s) is a hallmark of endocrine-resistant breast cancer (BCa) progression. Here, we report that miR-1271 was significantly down-regulated in letrozole-resistant BCa tissues and in letrozole-resistant BCa… read more here.
Keywords: letrozole resistance; bca; mir; expression ... See more keywords
MicroRNA-1271-5p inhibits the tumorigenesis of ovarian cancer through targeting E2F5 and negatively regulates the mTOR signaling pathway.
Sign Up to like & getrecommendations! Published in 2020 at "Panminerva medica"
DOI: 10.23736/s0031-0808.20.03939-7
Abstract: BACKGROUND MicroRNA-1271-5p (miR-1271-5p) has been reported to participate in the progression of many human cancers. However, the role of miR-1271-5p still remains unclear in ovarian cancer (OC). Therefore, we explored the effect of miR-1271-5p on… read more here.
Keywords: mtor; ovarian cancer; mir 1271; mir ... See more keywords
Progression of Thoracic Aortic Dissection Is Aggravated by the hsa_circ_0007386/miR-1271-5P/IGF1R/AKT Axis via Induction of Arterial Smooth Muscle Cell Apoptosis
Sign Up to like & getrecommendations! Published in 2023 at "Biomedicines"
DOI: 10.3390/biomedicines11020571
Abstract: Background: The molecular mechanisms associated with thoracic aortic dissection (TAD) remain poorly understood. A comprehensive high-throughput sequencing-based analysis of the circRNA–miRNA–mRNA competitive endogenous RNA (ceRNA) regulatory network in TAD has not been conducted. The purpose… read more here.
Keywords: mir 1271; circ 0007386; 0007386 mir; hsa circ ... See more keywords
Circular RNA ABCB10 promotes cell proliferation and invasion, but inhibits apoptosis via regulating the microRNA-1271-mediated Capn4/Wnt/β-catenin signaling pathway in epithelial ovarian cancer
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DOI: 10.3892/mmr.2021.12026
Abstract: Circular RNA ABCB10 (circ-ABCB10) modulates cellular functions and microRNA (miR)-1271 in epithelial ovarian cancer (EOC). The present study aimed to investigate the interaction between circ-ABCB10 and miR-1271 in regulating EOC cellular function and the calpain… read more here.
Keywords: catenin signaling; mir 1271; abcb10; circ abcb10 ... See more keywords
MicroRNA-1271 inhibits cellular proliferation of hepatocellular carcinoma.
Sign Up to like & getrecommendations! Published in 2017 at "Oncology letters"
DOI: 10.3892/ol.2017.7052
Abstract: Hepatocellular carcinoma (HCC) is one of the most common causes of cancer-associated mortality worldwide, particularly in China. MicroRNAs (miRs) serve important roles in the pathogenesis of HCC. The present study investigated the function of miR-1271… read more here.
Keywords: hepatocellular carcinoma; hcc; mir 1271; proliferation ... See more keywords
MicroRNA-1271 inhibits proliferation and promotes apoptosis of multiple myeloma cells through inhibiting smoothened-mediated Hedgehog signaling pathway.
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DOI: 10.3892/or.2016.5304
Abstract: MicroRNAs (miRNAs) have emerged as important regulators in multiple myeloma (MM). miR-1271 is a tumor suppressor in many cancer types. However, the biological role of miR-1271 in MM remains unclear. In the present study, we… read more here.
Keywords: hedgehog signaling; mir; proliferation; multiple myeloma ... See more keywords