LncRNA FOXD3‐AS1 aggravates myocardial ischemia/reperfusion injury by inactivating the Redd1/AKT/GSK3β/Nrf2 signaling pathway via the miR‐128/TXNIP axis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23218
Abstract: Long noncoding RNA forkhead box D3‐antisense RNA 1 (FOXD3‐AS1) is associated with cardiovascular diseases, but its roles in myocardial ischemia/reperfusion (I/R) injury and the related signaling pathway have not been fully reported. We aimed to… read more here.
Keywords: txnip; foxd3 as1; injury; mir 128 ... See more keywords
A single-nucleotide polymorphism in lnc-LAMC2-1:1 interferes with its interaction with miR-128 to alter the expression of deleted in colorectal cancer and its effect on the survival rate of subjects with ovarian cancer.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of cellular biochemistry"
DOI: 10.1002/jcb.29597
Abstract: This study aimed to identify the association between lnc-LAMC2-1:1 polymorphism rs2147578 and the recurrence of ovary cancer, as well as to study the underlying mechanism of rs2147578 in ovary cancer. Real-time polymerase chain reaction, Western… read more here.
Keywords: mir 128; lnc lamc2; expression; cancer ... See more keywords
Circular forms of dedicator of cytokinesis 1 promotes breast cancer progression by derepressing never in mitosis related kinase 2 via sponging miR-128-3p.
Sign Up to like & getrecommendations! Published in 2023 at "Environmental toxicology"
DOI: 10.1002/tox.23799
Abstract: The conjecture of breast cancer is uncertain because of its explosive growth and the complicated molecular mechanisms. Circular RNAs (circRNAs) are regulatory RNA sequences present in the genome and their regulatory mechanism involves the sponging… read more here.
Keywords: circular forms; expression; breast cancer; circdock1 ... See more keywords
LncRNA NEAT1 Enhances Glioma Progression via Regulating the miR-128-3p/ITGA5 Axis
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Neurobiology"
DOI: 10.1007/s12035-021-02474-y
Abstract: Accumulating evidences indicate that long non-coding RNA nuclear paraspeckle assembly transcript 1 (NEAT1) promotes the progression of glioma. In this study, we postulated that NEAT1 may act as a miR-128-3p sponge. Relative levels of NEAT1… read more here.
Keywords: mir 128; itga5 axis; glioma; 128 itga5 ... See more keywords
MicroRNA-128 contributes to the progression of gastric carcinoma through GAREM-mediated MAPK signaling activation.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.08.177
Abstract: Gastric carcinoma (GC) represents the most common malignant cancer and the second leading cause of cancer death worldwide. However, the molecular mechanisms and biological progression of GC remain unknown. In this study, we found that… read more here.
Keywords: gastric carcinoma; progression; mir 128; mapk signaling ... See more keywords
A MicroRNA Linking Human Positive Selection and Metabolic Disorders
Sign Up to like & getrecommendations! Published in 2020 at "Cell"
DOI: 10.1016/j.cell.2020.09.017
Abstract: Positive selection in Europeans at the 2q21.3 locus harboring the lactase gene has been attributed to selection for the ability of adults to digest milk to survive famine in ancient times. However, the 2q21.3 locus… read more here.
Keywords: positive selection; selection; mir 128; metabolic ... See more keywords
microRNA-128 inhibits the inflammatory responses by targeting TAB2 in miiuy croaker, Miichthysmiiuy.
Sign Up to like & getrecommendations! Published in 2020 at "Developmental and comparative immunology"
DOI: 10.1016/j.dci.2020.103976
Abstract: The inflammatory response is a self-defense process that fights the pathogen invasion by eliminating harmful stimuli. However, excessive inflammation may disrupt immune homeostasis, even causing chronic inflammation or autoimmune diseases. MicroRNAs (miRNAs) are a crucial… read more here.
Keywords: inflammatory responses; miiuy croaker; tab2; targeting tab2 ... See more keywords
miR-128 targets the CC chemokine ligand 18 gene (CCL18) in cutaneous malignant melanoma progression.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of dermatological science"
DOI: 10.1016/j.jdermsci.2018.06.011
Abstract: BACKGROUND The CC chemokine ligand 18 (CCL18) has a higher expression in some tumors, while the CCL18 level can be a marker of tumor progression and prognosis. We previously reported that the expression of CCL18… read more here.
Keywords: melanoma; chemokine ligand; mir 128; expression ... See more keywords
Inhibition of microRNA-128-3p attenuates hypercholesterolemia in mouse model.
Sign Up to like & getrecommendations! Published in 2020 at "Life sciences"
DOI: 10.1016/j.lfs.2020.118633
Abstract: AIMS Hypercholesterolemia remains a critical risk factor for cardiovascular diseases and there is an urgent need to develop effective alternative therapeutics. Herein, we investigated the effects of miR-128-3p inhibition on serum cholesterol levels using a… read more here.
Keywords: inhibition; cholesterol; serum; mir 128 ... See more keywords
The RNA-binding protein ARPP21 controls dendritic branching by functionally opposing the miRNA it hosts
Sign Up to like & getrecommendations! Published in 2018 at "Nature Communications"
DOI: 10.1038/s41467-018-03681-3
Abstract: About half of mammalian miRNA genes lie within introns of protein-coding genes, yet little is known about functional interactions between miRNAs and their host genes. The intronic miRNA miR-128 regulates neuronal excitability and dendritic morphology… read more here.
Keywords: arpp21 controls; arpp21; rna binding; mir 128 ... See more keywords
MiR-128 inhibits the osteogenic differentiation in osteoporosis by down-regulating SIRT6 expression
Sign Up to like & getrecommendations! Published in 2019 at "Bioscience Reports"
DOI: 10.1042/bsr20191405
Abstract: Background: MicroRNAs (miRNAs) are involved in the regulation of osteogenic differentiation and chondrification in vivo. The purpose of the present study was to explore the potential mechanism of miR-128 in osteoporosis (OP). Methods: Quantitative real-time… read more here.
Keywords: expression; osteogenic differentiation; c2c12 cells; differentiation ... See more keywords