Diagnostic Value of a Group of MicroRNA Genes Hypermethylated in Ovarian Carcinoma
Sign Up to like & getrecommendations! Published in 2018 at "Bulletin of Experimental Biology and Medicine"
DOI: 10.1007/s10517-018-4326-0
Abstract: The study was designed to determine genes of microRNAs hypermethylated in malignant ovarian tumors and to select new diagnostic and prognostic markers of the disease and effective system of markers. Using methyl-specific PCR and a… read more here.
Keywords: mir mir; 129 mir; mir 129; mir ... See more keywords
Elevated miR-129-5p attenuates hepatic fibrosis through the NF-κB signaling pathway via PEG3 in a carbon CCl4 rat model.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of molecular histology"
DOI: 10.1007/s10735-020-09949-7
Abstract: Hepatic fibrosis is a reversible scaring response to chronic liver injury. MicroRNA (miR)-129-5p might regulate fibrosis-related gene expression. This study is performed to decipher, potential of miR-129-5p to influence the progression of hepatic fibrosis in… read more here.
Keywords: peg3; fibrosis; mir 129; signaling pathway ... See more keywords
FGD5-AS1 facilitates glioblastoma progression by activation of Wnt/β-catenin signaling via regulating miR-129-5p/HNRNPK axis.
Sign Up to like & getrecommendations! Published in 2020 at "Life sciences"
DOI: 10.1016/j.lfs.2020.117998
Abstract: AIMS Accumulating evidence elucidates the biological significance of long non-coding RNA (lncRNAs) in tumorigenesis and development. FGD5 antisense RNA 1 (FGD5-AS1) was previously revealed as an oncogene in several types of malignancies. However, the roles… read more here.
Keywords: mir 129; fgd5 as1; as1; hnrnpk ... See more keywords
Long non-coding RNA MALAT1 promotes the proliferation and migration of Schwann cells by elevating BDNF through sponging miR-129-5p.
Sign Up to like & getrecommendations! Published in 2020 at "Experimental cell research"
DOI: 10.1016/j.yexcr.2020.111937
Abstract: The proliferation and migration of Schwann cells contribute to nerve regeneration after peripheral nerve injury (PNI). In recent years, roles of long non-coding RNAs (lncRNAs) in PNI have been gradually uncovered. However, a highly conserved… read more here.
Keywords: proliferation migration; mir 129; schwann cells; malat1 ... See more keywords
Resveratrol Enhances Wound Healing in Type 1 Diabetes Mellitus by Promoting the Expression of Extracellular Vesicle-Carried MicroRNA-129 Derived from Mesenchymal Stem Cells.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.1c00248
Abstract: Recent studies have shown the promotive effect of resveratrol on wound healing. This study aims to explore the underlying molecular mechanism of resveratrol in type 1 diabetes mellitus (T1DM) through microRNA (miR)-129-containing extracellular vesicles (EVs)… read more here.
Keywords: expression; type diabetes; diabetes mellitus; resveratrol ... See more keywords
Protein kinase C-alpha suppresses autophagy and induces neural tube defects via miR-129-2 in diabetic pregnancy
Sign Up to like & getrecommendations! Published in 2017 at "Nature Communications"
DOI: 10.1038/ncomms15182
Abstract: Gene deletion-induced autophagy deficiency leads to neural tube defects (NTDs), similar to those in diabetic pregnancy. Here we report the key autophagy regulators modulated by diabetes in the murine developing neuroepithelium. Diabetes predominantly leads to… read more here.
Keywords: tube defects; diabetic pregnancy; suppresses autophagy; mir 129 ... See more keywords
Promoting role of circ-Jarid2/miR-129-5p/Celf1 axis in cardiac hypertrophy
Sign Up to like & getrecommendations! Published in 2020 at "Gene Therapy"
DOI: 10.1038/s41434-020-0165-5
Abstract: Cardiac hypertrophy is imposed much pressure on heart and threatening our live. Previous study suggested that dysregulation of Celf1 is largely connecting to neonatal cardiac dysfunction. Hence, we aimed to explore the precise function and… read more here.
Keywords: cardiac hypertrophy; mir 129; hypertrophy; circ jarid2 ... See more keywords
MiR-129-5p regulates cell proliferation and apoptosis via IGF-1R/Src/ERK/Egr-1 pathway in RA-fibroblast-like synoviocytes
Sign Up to like & getrecommendations! Published in 2019 at "Bioscience Reports"
DOI: 10.1042/bsr20192009
Abstract: Abstract It is reported that miR-129-5p plays an important role in various diseases, but its effect on rheumatoid arthritis (RA) and the potential mechanism remain to be clarified. In the present research, we aimed to… read more here.
Keywords: cell proliferation; erk egr; apoptosis; src erk ... See more keywords
MicroRNA-129-5p alleviates spinal cord injury in mice via suppressing the apoptosis and inflammatory response through HMGB1/TLR4/NF-κB pathway
Sign Up to like & getrecommendations! Published in 2020 at "Bioscience Reports"
DOI: 10.1042/bsr20193315
Abstract: Abstract Secondary injury after spinal cord injury (SCI) is one reversible pathological change mainly involving excessive inflammatory response and neuro-apoptosis. Since in recent years, microRNAs (miRNAs) have been proposed as novel regulators of inflammation in… read more here.
Keywords: tlr4; inflammatory response; apoptosis; mir 129 ... See more keywords
NORAD accelerates chemo-resistance of non-small-cell lung cancer via targeting at miR-129-1-3p/SOX4 axis
Sign Up to like & getrecommendations! Published in 2020 at "Bioscience Reports"
DOI: 10.1042/bsr20193489
Abstract: Abstract Substantial researches indicated that long non-coding RNAs (lncRNAs) exerted profound effects on chemo-resistance in cancer treatment. Nonetheless, the role of NORAD in non-small-cell lung cancer (NSCLC) remains unclear. In the present study, we chose… read more here.
Keywords: chemo resistance; cancer; cell; mir 129 ... See more keywords
The expression of miR-129-5p and its target genes in the skin of goats
Sign Up to like & getrecommendations! Published in 2020 at "Animal Biotechnology"
DOI: 10.1080/10495398.2020.1730392
Abstract: Abstract Coat color is one of the major quality traits of animals, and miR-129-5p acts as an important regulator for melanin biosynthesis in mammals. In this study, real-time PCR and western blotting were used to… read more here.
Keywords: target genes; genes skin; mir 129; coat color ... See more keywords