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   Articles with "mir 130a" as a keyword



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Antiapoptotic and anti‐inflammatory effects of Pparγ agonist, pioglitazone, reversed Dox‐induced cardiotoxicity through mediating of miR‐130a downregulation in C57BL/6 mice

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recommendations! Published in 2022 at "Journal of Biochemical and Molecular Toxicology"

DOI: 10.1002/jbt.23041

Abstract: Doxorubicin (Dox) is an antitumor agent widely used in cancer therapy, with notable side effects of cardiac toxicity. Peroxisome proliferator‐activated receptor γ (PPARγ), is a transcriptional factor with antiapoptotic and anti‐inflammatory properties. Recently we indicated… read more here.

Keywords: ppar; mir 130a; dox; dox induced ... See more keywords
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MiR-130a/Ndrg2 Axis Inhibits the Proliferation of Fibroblast-Like Synoviocytes in Rheumatoid Arthritis.

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recommendations! Published in 2020 at "Inflammation"

DOI: 10.1007/s10753-019-01118-7

Abstract: Studies have found that N-myc downstream-regulated gene 2 (Ndrg2) is involved in the progression of rheumatoid arthritis (RA); however, the specific mechanism still remains unclear. Gene expression profiles in the tibial joints of the collagen-induced… read more here.

Keywords: 130a ndrg2; expression; rheumatoid arthritis; arthritis ... See more keywords
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Long noncoding RNA KB-1460A1.5 inhibits glioma tumorigenesis via miR-130a-3p/TSC1/mTOR/YY1 feedback loop.

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recommendations! Published in 2021 at "Cancer letters"

DOI: 10.1016/j.canlet.2021.10.033

Abstract: Long noncoding RNAs (lncRNAs) have been shown to be closely related to cancer progression and therapy. However, the clinical significance of lncRNAs and the mechanisms by which they function in glioma are largely unknown. In… read more here.

Keywords: tsc1; 1460a1 inhibits; inhibits glioma; mtor ... See more keywords
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Identification of the global miR-130a targetome reveals a role for TBL1XR1 in hematopoietic stem cell self-renewal and t(8;21) AML.

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recommendations! Published in 2022 at "Cell reports"

DOI: 10.1016/j.celrep.2022.110481

Abstract: Gene expression profiling and proteome analysis of normal and malignant hematopoietic stem cells (HSCs) point to shared core stemness properties. However, discordance between mRNA and protein signatures highlights an important role for post-transcriptional regulation by… read more here.

Keywords: mir 130a; mir; self renewal; role ... See more keywords
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Circular RNA hsa_circ_0054537 sponges miR-130a-3p to promote the progression of Renal Cell Carcinoma through regulating cMet pathway.

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recommendations! Published in 2020 at "Gene"

DOI: 10.1016/j.gene.2020.144811

Abstract: Renal cell carcinoma (RCC) is one of the most common tumors of the urinary system, seriously impacting public health. CircRNAs have been indicated as potentially critical mediators in tumorigenesis and cancer progression. However, their specific… read more here.

Keywords: hsa circ; circ 0054537; mir 130a; cell ... See more keywords
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Bta-miR-130a/b regulates preadipocyte differentiation by targeting PPARG and CYP2U1 in beef cattle.

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recommendations! Published in 2018 at "Molecular and cellular probes"

DOI: 10.1016/j.mcp.2018.10.002

Abstract: Deposition of intramuscular fat (IMF) is one of the most important traits for the evaluation of beef carcass quality grade. MicroRNA (miRNA) is an endogenous non-coding RNA that can play a role in the post-transcriptional… read more here.

Keywords: pparg cyp2u1; mir 130a; bta mir; differentiation ... See more keywords
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Hepatic exosome-derived miR-130a-3p attenuates glucose tolerance via suppressing PHLPP2 gene in adipocyte.

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recommendations! Published in 2019 at "Metabolism: clinical and experimental"

DOI: 10.1016/j.metabol.2019.154006

Abstract: OBJECTIVE Glucose and lipid metabolism disorder is a major risk factor for type II diabetes and cardiovascular diseases. Evidence has indicated that the interplay between the liver and adipose tissue is crucial in maintaining energy… read more here.

Keywords: hepatic exosome; mice; derived mir; mir 130a ... See more keywords
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miR-130a/TGF-β1 axis is involved in sow fertility by controlling granulosa cell apoptosis.

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recommendations! Published in 2020 at "Theriogenology"

DOI: 10.1016/j.theriogenology.2020.08.015

Abstract: TGF-β1 is a ligand of the TGF-β superfamily and an important cytokine that regulates ovarian functions including follicular development, steroid production, ovulation, luteinization, and female fertility. However, little is known about the regulation of TGF-β1… read more here.

Keywords: tgf axis; tgf; mir 130a; 130a tgf ... See more keywords
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SOX9/miR-130a/CTR1 axis modulates DDP-resistance of cervical cancer cell

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recommendations! Published in 2018 at "Cell Cycle"

DOI: 10.1080/15384101.2017.1395533

Abstract: ABSTRACT Cisplatin (DDP) -based chemotherapy is a standard strategy for cervical cancer, while chemoresistance remains a huge challenge. Copper transporter protein 1 (CTR1), a copper influx transporter required for high affinity copper (probably reduced Cu… read more here.

Keywords: chemoresistance; cervical cancer; ctr1; cancer ... See more keywords
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MiR-130a-5p prevents angiotensin II-induced podocyte apoptosis by modulating M-type phospholipase A2 receptor

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recommendations! Published in 2018 at "Cell Cycle"

DOI: 10.1080/15384101.2018.1542901

Abstract: ABSTRACT Podocyte apoptosis is considered as the important element that promotes the development and progress of membranous nephropathy (MN). Unfortunately, the underlying mechanism of podocytes apoptosis in MN remains elusive. We compared the renal expressions… read more here.

Keywords: podocyte apoptosis; apoptosis; phospholipase receptor; type phospholipase ... See more keywords
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MiR-130a in the adipogenesis of human SGBS preadipocytes and its susceptibility to androgen regulation

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recommendations! Published in 2020 at "Adipocyte"

DOI: 10.1080/21623945.2020.1750256

Abstract: ABSTRACT Objectives: Adipogenesis is the differentiation process generating mature adipocytes from undifferentiated mesenchymal stem cells. The differentiation can be inhibited by androgens, although knowledge about intracellular effectors of this inhibition is scarce. Recently, androgen-regulated microRNAs… read more here.

Keywords: mir 301; androgen; mir; adipogenesis ... See more keywords