microRNA‐132 inhibits cardiomyocyte apoptosis and myocardial remodeling in myocardial infarction by targeting IL‐1β
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.29175
Abstract: The patients suffering from myocardial infarction (MI) undergo cardiac remodeling with the features of expanded myocardial infarct size and dilated left ventricle. Multiple microRNAs (miRNAs) are emerged as crucial modulators to participate in the remodeling… read more here.
Keywords: mir 132; myocardial remodeling; myocardial infarction; 132 inhibits ... See more keywords
miR‐132‐3p promotes heat stimulation‐induced esophageal squamous cell carcinoma tumorigenesis by targeting KCNK2
Sign Up to like & getrecommendations! Published in 2023 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.23504
Abstract: Epidemiological evidence supports that consumption of high‐temperature food and beverages is an important risk factor for esophageal squamous cell carcinoma (ESCC); however, the underlying mechanism still remains unclear. Here, we established a series of animal… read more here.
Keywords: heat stimulation; squamous cell; mir 132; esophageal squamous ... See more keywords
The Stress-Responding miR-132-3p Shows Evolutionarily Conserved Pathway Interactions
Sign Up to like & getrecommendations! Published in 2017 at "Cellular and Molecular Neurobiology"
DOI: 10.1007/s10571-017-0515-z
Abstract: MicroRNAs (miRNAs) are small non-coding RNA chains that can each interact with the 3′-untranslated region of multiple target transcripts in various organisms, humans included. MiRNAs tune entire biological pathways, spanning stress reactions, by regulating the… read more here.
Keywords: mir 132; evolutionarily conserved; stress related; stress ... See more keywords
miR-132 Regulates PTSD-like Behaviors in Rats Following Single-Prolonged Stress Through Fragile X-Related Protein 1
Sign Up to like & getrecommendations! Published in 2020 at "Cellular and Molecular Neurobiology"
DOI: 10.1007/s10571-020-00854-x
Abstract: Fragile X-related protein 1 (FXR1) is a member of the fragile X family of RNA-binding proteins, which regulates a number of neurological and neuropsychiatric disorders such as fragile X syndrome, and is expected as a… read more here.
Keywords: protein; mir 132; like behaviors; stress ... See more keywords
MicroRNA-132 targeting PTEN contributes to cilostazol-promoted vascular smooth muscle cell differentiation.
Sign Up to like & getrecommendations! Published in 2018 at "Atherosclerosis"
DOI: 10.1016/j.atherosclerosis.2018.04.030
Abstract: BACKGROUND AND AIMS Cilostazol, beyond its antiplatelet effect, is also capable of promoting vascular smooth muscle cell (VSMC) differentiation. The aim of this study was to explore the potential role of PTEN, known to associate… read more here.
Keywords: vsmc differentiation; mir 132; vascular smooth; differentiation ... See more keywords
Brown adipocyte-derived exosomal miR-132-3p suppress hepatic Srebf1 expression and thereby attenuate expression of lipogenic genes.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.05.090
Abstract: Recent evidence has revealed a novel signaling mechanism through which brown adipose tissue (BAT)-derived exosomal microRNAs (miRNAs) influence hepatic gene expression. Here, we uncover neuronal control of these miRNAs and identify exosomal miR-132-3p as a… read more here.
Keywords: mir 132; srebf1; derived exosomal; expression ... See more keywords
Long non-coding RNA LINC00160 functions as a decoy of microRNA-132 to mediate autophagy and drug resistance in hepatocellular carcinoma via inhibition of PIK3R3.
Sign Up to like & getrecommendations! Published in 2020 at "Cancer letters"
DOI: 10.1016/j.canlet.2020.02.014
Abstract: The introduction of long non-coding RNAs (lncRNAs) has revolutionized the treatment of hepatocellular carcinoma (HCC). Thus, in the present study, we aimed to evaluate the effect of a newly found lncRNA, LINC00160, on autophagy and… read more here.
Keywords: drug resistance; hcc; mir 132; autophagy drug ... See more keywords
Nimodipine attenuates tau phosphorylation at Ser396 via miR‐132/GSK‐3&bgr; pathway in chronic cerebral hypoperfusion rats
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Pharmacology"
DOI: 10.1016/j.ejphar.2017.10.027
Abstract: ABSTRACT Chronic cerebral hypofusion (CCH) promotes hyperphosphorylation of tau proteins, a key neuropathological trait that reflects neurodegenerative disorders. Nimodipine, an L‐type calcium channel antagonist, has been reported to show neuroprotective effects. In this study, we… read more here.
Keywords: tau phosphorylation; gsk bgr; phosphorylation ser396; mir 132 ... See more keywords
Klotho inhibits angiotensin II-induced cardiac hypertrophy, fibrosis, and dysfunction in mice through suppression of transforming growth factor-β1 signaling pathway.
Sign Up to like & getrecommendations! Published in 2019 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2019.172549
Abstract: Recent studies have revealed critical roles of transforming growth factor-β1 (TGF-β1) and microRNA-132 (miR-132), a downstream mediator of TGF-β1, in the pathogenesis of cardiac remodeling. In this study, we tested whether the antiaging protein klotho… read more here.
Keywords: ang induced; induced cardiac; mir 132; growth factor ... See more keywords
MiR-132 regulated olfactory bulb proteins linked to olfactory learning in greater short-nosed fruit bat Cynopterus sphinx.
Sign Up to like & getrecommendations! Published in 2018 at "Gene"
DOI: 10.1016/j.gene.2018.05.107
Abstract: Earlier, we showed that micro RNA-132 (miR-132) regulate the immediate early genes (IEGs) in the olfactory bulb (OB) of fruit bat Cynopterus sphinx during olfactory learning. This study was designed to examine whether the miR-132… read more here.
Keywords: analysis; olfactory learning; mir 132; olfactory bulb ... See more keywords
Upregulation of MIR-132-5P via nicotine enhances cell survival in PC12 cells by targeting the anti-apoptotic protein BCL-2
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the Neurological Sciences"
DOI: 10.1016/j.jns.2019.10.1117
Abstract: Objective Activation of nicotinic acetylcholine receptors (nAChRs) results in neuroprotection via a poorly understood molecular mechanism. Herein, we aimed to investigate the effect of nAChR stimulation with nicotine on the regulation of miRNA expression and… read more here.
Keywords: protein; mir 132; cell survival; anti apoptotic ... See more keywords