hsa‐mir‐133a‐2 promotes the proliferation and invasion of cervical cancer cells by targeting the LAMB3‐mediated PI3K/ATK pathway
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.5380
Abstract: Cervical cancer, one of the common types of malignant tumors progressed in women, is on the rise in developing countries. Numerous previous studies have demonstrated that hsa‐mir‐133a‐2 miRNA is abnormally expressed in cervical cancer cells.… read more here.
Keywords: cervical cancer; cancer; proliferation invasion; hsa mir ... See more keywords
Aryl hydrocarbon‐estrogen alpha receptor‐dependent expression of miR‐206, miR‐27b, and miR‐133a suppress cell proliferation and migration in MCF‐7 cells
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.22304
Abstract: The underlying functions of miR‐206, miR‐133a, miR‐27b, and miR‐21, and their link to the estrogen receptor alpha (ERα) and aryl hydrocarbon receptor (AhR) signaling pathways remain largely unexplored. In this study, we detect the expression… read more here.
Keywords: mir; mir 206; mir 133a; mir 27b ... See more keywords
LncRNA XIST Promotes Pancreatic Cancer Proliferation Through miR‐133a/EGFR
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.25988
Abstract: According to recent studies, long non‐coding RNA X‐inactive specific transcript (XIST) is involved in the development and progression of many malignant tumors including pancreatic cancer. We validated the detailed role of XIST in human pancreatic… read more here.
Keywords: egfr; xist; pancreatic cancer; proliferation ... See more keywords
Reversine promotes browning of white adipocytes by suppressing miR‐133a
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.27148
Abstract: Brown adipocytes are characterized by a high number of uncoupling protein 1 (UCP1)‐positive mitochondrial content and increased thermogenic capacity. As UCP1‐enriched cells can consume lipids by generating heat, browning of white adipocytes is now highlighted… read more here.
Keywords: 133a reversine; white adipocytes; mir 133a; browning white ... See more keywords
miR‐133a‐3p suppresses cell proliferation, migration, and invasion and promotes apoptosis in esophageal squamous cell carcinoma
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.27896
Abstract: This study aimed to investigate the expression levels of miR‐133a‐3p and collagen type I α 1 (COL1A1) in esophageal squamous cell carcinoma (ESCC) to find out the relationship between miR‐133a‐3p and COL1A1 and their influence… read more here.
Keywords: cell carcinoma; squamous cell; mir 133a; esophageal squamous ... See more keywords
miRNA‐1 and miRNA‐133a are involved in early commitment of pluripotent stem cells and demonstrate antagonistic roles in the regulation of cardiac differentiation
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Tissue Engineering and Regenerative Medicine"
DOI: 10.1002/term.1977
Abstract: miRNA‐1 (miR‐1) and miRNA‐133a (miR‐133a) are muscle‐specific miRNAs that play an important role in heart development and physiopathology. Although both miRNAs have been broadly studied during cardiogenesis, the mechanisms by which miR‐1 and miR‐133a could… read more here.
Keywords: mir; differentiation; pluripotent stem; mir 133a ... See more keywords
Generating Ins2+/-/miR-133aTg Mice to Model miRNA-Driven Cardioprotection of Human Diabetic Heart.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1008-4_8
Abstract: Diabetes mellitus (DM) is caused either due to insulin deficiency (T1DM) or insulin resistance (T2DM). DM increases the risk of heart failure by diabetic cardiomyopathy (DMCM), a cardiac muscle disorder that leads to a progressive decline… read more here.
Keywords: heart; mir 133a; dmcm; mice ... See more keywords
Downregulating LncRNA XIST attenuated contrast-induced nephropathy injury via regulating miR-133a-3p/NLRP3 axis
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Thrombosis and Thrombolysis"
DOI: 10.1007/s11239-020-02369-0
Abstract: Long non-coding RNA X-inactive specific transcript (LncRNA XIST) is involved in several diseases. However, the molecular mechanism of XIST and its relation with miR-133a-3p in contrast-induced nephropathy (CIN) remained vague. Sprague–Dawley (SD) rats were assigned… read more here.
Keywords: xist; contrast induced; mir 133a; induced nephropathy ... See more keywords
Upregulation of miR-133a-3p in the Sciatic Nerve Contributes to Neuropathic Pain Development
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Neurobiology"
DOI: 10.1007/s12035-020-01999-y
Abstract: The micro (mi)RNAs expressed in the sciatic nerve of streptozotocin (STZ)-induced diabetic rats were evaluated in terms of their therapeutic potential in patients with diabetic neuropathic pain (DNP). Relative miRNA expression in sciatic nerve with… read more here.
Keywords: sciatic nerve; 133a sciatic; mir 133a; neuropathic pain ... See more keywords
miR-133a-3p attenuates cardiomyocyte hypertrophy through inhibiting pyroptosis activation by targeting IKKε.
Sign Up to like & getrecommendations! Published in 2020 at "Acta histochemica"
DOI: 10.1016/j.acthis.2020.151653
Abstract: OBJECTIVE Cardiac hypertrophy is an adaptive response to physiological and pathological stimuli, the latter of which frequently progresses to valvulopathy, heart failure and sudden death. Recent reports revealed that pyroptosis is involved in regulating multiple… read more here.
Keywords: cardiac hypertrophy; cardiomyocyte hypertrophy; pyroptosis activation; hypertrophy ... See more keywords
Downregulation of miR-133a contributes to the cardiac developmental toxicity of trichloroethylene in zebrafish.
Sign Up to like & getrecommendations! Published in 2020 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2020.126610
Abstract: Trichloroethylene (TCE), a widely used organic solvent, is a common environmental pollutant. Increasing evidence indicates that maternal TCE exposure is associated with congenital cardiac defects, but the underlining mechanisms remain largely unknown. In this study,… read more here.
Keywords: heart; tce; trichloroethylene; mir 133a ... See more keywords