miR‐134 targets PDCD7 to reduce E‐cadherin expression and enhance oral cancer progression
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Cancer"
DOI: 10.1002/ijc.31638
Abstract: Oral squamous cell carcinoma (OSCC) is a common malignancy worldwide. This study clarified the oncogenic role of miR‐134 in OSCC. Reporter assays, using both wild‐type and mutant constructs, confirmed that Programmed Cell Death 7 (PDCD7)… read more here.
Keywords: pdcd7; mir 134; cad; expression ... See more keywords
MiR‐134‐5p attenuates neuropathic pain progression through targeting Twist1
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.27486
Abstract: Neuropathic pain is a kind of chronic pain because of dysfunctions of somatosensory nerve system. Recently, many studies have demonstrated that microRNAs (miRs) play crucial roles in neuropathic pain development. This study was designed to… read more here.
Keywords: pain progression; mir 134; twist1; neuropathic pain ... See more keywords
Protective effect of microRNA‐134‐3p on multiple sclerosis through inhibiting PRSS57 and promotion of CD34+ cell proliferation in rats
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.29643
Abstract: MicroRNAs (miRs) have been extensively studied for their involvement in multiple sclerosis (MS). We investigated the involvement of miR‐134‐3p on MS. The MS rat model was established, and positive expression of interleukin‐17 (IL‐17) was detected… read more here.
Keywords: cd34 cell; cell proliferation; prss57; mir 134 ... See more keywords
Suppression of long noncoding RNA NCK1‐AS1 increases chemosensitivity to cisplatin in cervical cancer
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.27198
Abstract: Cervical cancer remains a serious health problem till now, with nearly 500,000 women cases diagnosed each year around the world. Long noncoding RNA (lncRNA) is a novel class of RNA transcripts (>200 nucleotides in length)… read more here.
Keywords: nck1 as1; mir 134; cervical cancer; rna ... See more keywords
Long non-coding RNA LINC00858 aggravates the oncogenic phenotypes of ovarian cancer cells through miR-134-5p/RAD18 signaling
Sign Up to like & getrecommendations! Published in 2020 at "Archives of Gynecology and Obstetrics"
DOI: 10.1007/s00404-020-05722-z
Abstract: Ovarian cancer is a common gynecological cancer. Herein, we focused on the function and probable mechanisms of LINC00858 in ovarian cancer. Real-time quantitative polymerase chain reaction (RT-qPCR) was employed for detecting the expression of LINC00858,… read more here.
Keywords: mir 134; linc00858; ovarian cancer; cancer ... See more keywords
Circular RNA circDLGAP4 exerts neuroprotective effects via modulating miR-134-5p/CREB pathway in Parkinson's disease.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.11.102
Abstract: Parkinson's disease (PD) is a neurodegenerative disease which is characterized by the substantia nigra dopaminergic neurons denatured. Circular RNA (circRNA) DLGAP4 (circDLGAP4) was found to have neuroprotective effect. In this study, we aimed to investigate… read more here.
Keywords: 134 creb; mir 134; creb; parkinson disease ... See more keywords
MiR-134 modulates chronic stress-induced structural plasticity and depression-like behaviors via downregulation of Limk1/cofilin signaling in rats
Sign Up to like & getrecommendations! Published in 2018 at "Neuropharmacology"
DOI: 10.1016/j.neuropharm.2018.01.009
Abstract: ABSTRACT Increasing evidence has suggested that depression is a neuropsychiatric condition associated with neuroplasticity within specific brain regions. However, the mechanisms by which neuroplasticity exerts its effects in depression remain largely uncharacterized. In the present… read more here.
Keywords: depression; limk1 cofilin; mir 134; like behaviors ... See more keywords
Dendrobium nobile Lindl. polysaccharides reduce cerebral ischemia/reperfusion injury in mice by increasing myeloid cell leukemia 1 via the downregulation of miR-134.
Sign Up to like & getrecommendations! Published in 2020 at "NeuroReport"
DOI: 10.1097/wnr.0000000000001562
Abstract: OBJECTIVE The traditional Chinese medicine, Dendrobium nobile Lindl. polysaccharides (DNLP), reportedly has neuroprotective effects. However, its effects following ischemic stroke remain unclear. This study aimed to explore the role and mechanism of DNLP in experimental… read more here.
Keywords: mir 134; dendrobium nobile; reperfusion; nobile lindl ... See more keywords
LINC00470 promotes tumour proliferation and invasion, and attenuates chemosensitivity through the LINC00470/miR‐134/Myc/ABCC1 axis in glioma
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.15846
Abstract: Glioma is the most common primary malignant tumour in the brain; temozolomide (TMZ) is the most prevalent chemotherapeutic drug currently used to combat this cancer. We reported previously that the long intergenic non‐protein coding RNA… read more here.
Keywords: proliferation invasion; glioma; mir 134; expression ... See more keywords
Hsa‐miR‐134‐5p predicts cardiovascular risk in circulating mononuclear cells and improves angiogenic action of senescent endothelial progenitor cells
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.18523
Abstract: This research explores the role of microRNA in senescence of human endothelial progenitor cells (EPCs) induced by replication. Hsa‐miR‐134‐5p was found up‐regulated in senescent EPCs where overexpression improved angiogenic activity. Hsa‐miR‐134‐5p, which targeted transforming growth… read more here.
Keywords: hsa mir; senescent epcs; risk; mir 134 ... See more keywords
Electroacupuncture Regulates Hippocampal Synaptic Plasticity via miR-134-Mediated LIMK1 Function in Rats with Ischemic Stroke
Sign Up to like & getrecommendations! Published in 2017 at "Neural Plasticity"
DOI: 10.1155/2017/9545646
Abstract: MircoRNAs (miRs) have been implicated in learning and memory, by regulating LIM domain kinase (LIMK1) to induce synaptic-dendritic plasticity. The study aimed to investigate whether miRNAs/LIMK1 signaling was involved in electroacupuncture- (EA-) mediated synaptic-dendritic plasticity… read more here.
Keywords: mediated limk1; mir 134; dendritic plasticity; synaptic dendritic ... See more keywords