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Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.26819
Abstract: Plenty of microRNAs have been identified as critical mediators in atherosclerosis progression, which is still a great threat to human health. Oxidative stress and inflammation have been implicated to contribute a lot to atherosclerosis development.…
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Keywords:
135a represses;
mir 135a;
represses oxidative;
atherosclerosis ... See more keywords
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Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.28508
Abstract: Aberrant microRNAs are widely identified in multiple cancers, including lung cancer. miR‐135a‐5p can function as a significant tumor regulator in diverse cancers via impacting multiple genes in oncogenic pathways. Nevertheless, the biological role of miR‐135a‐5p…
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Keywords:
loxl4;
mir 135a;
lung cancer;
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Published in 2023 at "Environmental Toxicology"
DOI: 10.1002/tox.23736
Abstract: Non‐small cell lung cancer (NSCLC) is the main histological subtype of lung cancer with a high incidence and mortality. Circular RNAs (circRNAs) exert vital functions in various cancers by acting as a sponge of miRNAs…
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Keywords:
lung cancer;
mir 135a;
function;
cell ... See more keywords
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Published in 2021 at "Molecular and cellular biochemistry"
DOI: 10.1007/s11010-020-04035-8
Abstract: Non-coding RNAs (ncRNAs) have shown to act as crucial mediators in atherosclerosis (AS) development. The purpose of our study was to explore the role of Astragaloside IV (ASV) and circular RNA_0000231 (circ_0000231) in AS using…
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Keywords:
circ 0000231;
mir 135a;
135a clic4;
targeting circ ... See more keywords
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Published in 2019 at "Neurochemical Research"
DOI: 10.1007/s11064-019-02904-3
Abstract: Paeoniflorin (PF) has been reported to possess neuroprotective influences on cognitive dysfunction illness. In current research, we attempted to probe into the protective influences of PF against H2O2-induced damage and the underlying regulating mechanisms on…
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Keywords:
induced oxidative;
microrna 135a;
mir 135a;
h2o2 induced ... See more keywords
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Published in 2017 at "Heart rhythm"
DOI: 10.1016/j.hrthm.2017.01.045
Abstract: BACKGROUND Complete atrioventricular block (CAVB) causes arrhythmogenic remodeling and increases the risk of torsades de pointes arrhythmias. MicroRNAs (miRNAs) are key regulators of gene expression that contribute to cardiac remodeling. OBJECTIVE The purpose of this…
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Keywords:
calcium exchanger;
gene expression;
sodium calcium;
expression ... See more keywords
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Published in 2020 at "Life sciences"
DOI: 10.1016/j.lfs.2020.118788
Abstract: AIM This study aimed to investigate the regulatory role of differentially-expressed circular RNAs (circRNAs) in mouse cardiomyocytes during doxorubicin (DOX)-induced cardiotoxicity. MAIN METHODS Two groups of mice were injected with equal volumes (0.1 mL) of normal…
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Keywords:
dox induced;
induced cardiotoxicity;
sponging mir;
cardiotoxicity ... See more keywords
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Published in 2021 at "Acta pharmacologica Sinica"
DOI: 10.1038/s41401-020-00608-x
Abstract: Proliferation of vascular smooth muscle cells (VSMCs) greatly contributes to vascular remodeling in hypertension. This study is to determine the roles and mechanisms of miR-135a-5p intervention in attenuating VSMC proliferation and vascular remodeling in spontaneously…
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Keywords:
proliferation;
vsmc proliferation;
shrs;
vascular remodeling ... See more keywords
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Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-06234-8
Abstract: Gallbladder carcinoma (GBC) is the most common malignant tumour in the biliary tract, but effective therapeutics are lacking. Based on our previous studies, miR-135a is a potential tool to inhibit GBC proliferation. In this study,…
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Keywords:
egfr cil;
cil mir;
anti egfr;
gallbladder carcinoma ... See more keywords
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Published in 2021 at "Bioengineered"
DOI: 10.1080/21655979.2021.1967579
Abstract: Acute lung injury (ALI) is the common and clinically severe complication. Dexmedetomidine (DEX) can protect against lipopolysaccharide (LPS)-induced ALI through anti-apoptosis, anti-inflammatory and immune regulatory actions. It is well documented that major causes of LPS-induced…
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Keywords:
xbp;
protective effect;
malat1;
mir 135a ... See more keywords
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Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2021.2024956
Abstract: ABSTRACT Hypertension is a severe public health problem that induces cardiac injury with alterations of gene expressions. The current study sought to evaluate the mechanism of microRNA(miR)-135a-5p in NOD-like receptor family pyrin domain containing 3…
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Keywords:
mir 135a;
cardiac inflammation;
inflammation fibrosis;
fibrosis ... See more keywords