Effects of XIST/miR‐137 axis on neuropathic pain by targeting TNFAIP1 in a rat model
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.26254
Abstract: Non‐coding RNAs have been reported to participate in the pathophysiology of neuropathic pain. The objective of our study was to investigate the biological role of XIST in neuropathic pain development. In our study, we identify… read more here.
Keywords: mir 137; pain; neuropathic pain; tnfaip1 ... See more keywords
Prognostic relevance of miR‐137 and its liver microenvironment regulatory target gene AFM in hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.27855
Abstract: MiR‐137 has been identified as potential hepatocellular carcinoma (HCC) prognostic biomarkers. Highly relevant HCC prognostic biomarkers may be derived from combinations of miR‐137 with its target genes involved in the regulation of liver microenvironment. This… read more here.
Keywords: mir 137; hcc; liver microenvironment; target ... See more keywords
MiR‐137 knockdown promotes the osteogenic differentiation of human adipose‐derived stem cells via the LSD1/BMP2/SMAD4 signaling network
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.29006
Abstract: MicroRNAs are a group of endogenous regulators that participate in several cellular physiological processes. However, the role of miR‐137 in the osteogenic differentiation of human adipose‐derived stem cells (hASCs) has not been reported. This study… read more here.
Keywords: mir 137; osteogenic differentiation; bmp2 smad4;
LncRNA NCK1-AS1 Promotes Malignant Cellular Phenotypes of Laryngeal Squamous Cell Carcinoma via miR-137/NCK1 Axis
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Biotechnology"
DOI: 10.1007/s12033-022-00469-1
Abstract: Increasing evidence demonstrates that many long noncoding RNAs (lncRNAs) are implicated with the development of laryngeal squamous cell carcinoma (LSCC). As shown by bioinformatics analysis, lncRNA non-catalytic region of tyrosine kinase adaptor protein 1-antisense 1… read more here.
Keywords: squamous cell; lscc; mir 137; nck1 as1 ... See more keywords
MiR-137 regulates low-intensity shear stress-induced human aortic endothelial cell apoptosis via JNK/AP-1 signaling.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of physiology and biochemistry"
DOI: 10.1007/s13105-021-00812-1
Abstract: The objective of this study is to evaluate the role of miR-137 in low-intensity shear stress-induced endoplasmic reticulum (ER) stress and cell apoptosis in human aortic endothelial cells (HAECs). HAECs were transfected with miR-137 mimic,… read more here.
Keywords: cell apoptosis; mir 137; stress; shear stress ... See more keywords
Oncogene LSD1 is epigenetically suppressed by miR-137 overexpression in human non-small cell lung cancer.
Sign Up to like & getrecommendations! Published in 2017 at "Biochimie"
DOI: 10.1016/j.biochi.2017.02.010
Abstract: PURPOSE We examined the epigenetic regulation of microRNA-137 (miR-137) on lysine-specific demethylase 1 (KDM1A, or LSD1) induced oncogenic effects in NSCLC. METHODS NSCLC cell lines, A549 and H460 cells were transfected with a mammalian LSD1 overexpression… read more here.
Keywords: mir 137; overexpression; mir; proliferation ... See more keywords
MicroRNA-137 and its downstream target LSD1 inversely regulate anesthetics-induced neurotoxicity in dorsal root ganglion neurons
Sign Up to like & getrecommendations! Published in 2017 at "Brain Research Bulletin"
DOI: 10.1016/j.brainresbull.2017.09.004
Abstract: PURPOSE Anesthetic reagents, such as bupivacaine (Bv), induce significant neurotoxicity in dorsal root ganglion neurons (DRGNs). In this study, we investigated the expression, function and cross-association of microRNA-137-3p (miR-137-3p) and lysine (K)-specific demethylase 1A (LSD1)… read more here.
Keywords: downstream target; mir 137; target lsd1; 137 downstream ... See more keywords
Upregulation of microRNA-137 expression by Slug promotes tumor invasion and metastasis of non-small cell lung cancer cells through suppression of TFAP2C.
Sign Up to like & getrecommendations! Published in 2017 at "Cancer letters"
DOI: 10.1016/j.canlet.2017.06.002
Abstract: The epithelial-mesenchymal transition (EMT) regulator, Slug, plays multifaceted roles in controlling lung cancer progression, but its downstream targets and mechanisms in promoting lung cancer progression have not been well defined. In particular, the miRNAs downstream… read more here.
Keywords: mir 137; lung cancer; slug; cancer cells ... See more keywords
miR-137 and miR-141 regulate tail defects in zebrafish embryos caused by triphenyl phosphate (TPHP).
Sign Up to like & getrecommendations! Published in 2020 at "Environmental pollution"
DOI: 10.1016/j.envpol.2020.114286
Abstract: Exposure to triphenyl phosphate (TPHP), an organophosphate flame retardants (OPFRs), caused developmental toxicity in zebrafish embryos. However, the underlying molecular mechanism at the epigenetic level is largely unknown. Based on developmental toxicity (i.e., mortality and… read more here.
Keywords: 137 mir; mir 137; mir 141; zebrafish embryos ... See more keywords
Neurobehavioral Phenotype Analysis in Molecular Intervention Models of Mir-137 Expression
Sign Up to like & getrecommendations! Published in 2017 at "European Neuropsychopharmacology"
DOI: 10.1016/j.euroneuro.2016.09.596
Abstract: Abstract Small non-coding microRNA (miRNA) coordinate mRNA translation and stability, and their dysregulation is thought to have significant consequences in psychiatric disorders. This hypothesis is clearly supported by strong genome-wide association of the MIR137 containing… read more here.
Keywords: phenotype; mir 137; neurobehavioral phenotype; phenotype analysis ... See more keywords
Dysregulated Expression of the MicroRNA miR‐137 and Its Target YBX1 Contribute to the Invasive Characteristics of Malignant Pleural Mesothelioma
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Thoracic Oncology"
DOI: 10.1016/j.jtho.2017.10.016
Abstract: Introduction: Malignant pleural mesothelioma (MPM) is an aggressive malignancy linked to asbestos exposure. On a genomic level, MPM is characterized by frequent chromosomal deletions of tumor suppressors, including microRNAs. MiR‐137 plays a tumor suppressor role… read more here.
Keywords: mir 137; mpm; ybx1; target ... See more keywords