miR‐139‐5p upregulation alleviated spontaneous recurrent epileptiform discharge‐induced oxidative stress and apoptosis in rat hippocampal neurons via regulating the Notch pathway
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DOI: 10.1002/cbin.11509
Abstract: Epilepsy was characterized by the occurrence of spontaneous recurrent epileptiform discharges (SREDs) in neurons. Previous studies suggested that microRNA (miR)−139‐5p and the Notch pathway were implicated in epilepsy; however, their interaction remained vague. Rat primary… read more here.
Keywords: mir 139; hippocampal neurons; apoptosis; 139 upregulation ... See more keywords
MiR‐139 promotes differentiation of bovine skeletal muscle‐derived satellite cells by regulating DHFR gene expression
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DOI: 10.1002/jcp.26817
Abstract: MicroRNAs play an important regulatory role in the proliferation and differentiation of skeletal muscle‐derived satellite cells (MDSCs). In particular, miR‐139 can inhibit tumor cell proliferation and invasion, and its expression is down‐regulated during C2C12 myoblast… read more here.
Keywords: mir 139; muscle; differentiation bovine; expression ... See more keywords
27‐Hydroxycholesterol enhanced osteoclastogenesis in lung adenocarcinoma microenvironment
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DOI: 10.1002/jcp.27883
Abstract: 27‐Hydroxycholesterol (27‐HC) has been implicated in the pathological process of estrogen receptor positive breast cancer. However, the role of 27‐HC in lung adenocarcinoma is still unclear. Because bone metastasis is a main reason for the… read more here.
Keywords: lung adenocarcinoma; mir 139; adenocarcinoma microenvironment; osteoclastogenesis lung ... See more keywords
The Smad2/3/4 complex binds miR‐139 promoter to modulate TGFβ‐induced proliferation and activation of human Tenon's capsule fibroblasts through the Wnt pathway
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.28011
Abstract: The activation and proliferation of human Tenon's fibroblasts (HTFs) play a vital role in the fibrosis in the pathology of the scar formation after the glaucoma filtration surgery. Transforming growth factor β1 (TGFβ1)/Smads signaling has… read more here.
Keywords: mir 139; activation proliferation; tgf induced; proliferation ... See more keywords
LINC01579 promotes cell proliferation by acting as a ceRNA of miR‐139‐5p to upregulate EIF4G2 expression in glioblastoma
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.28933
Abstract: Glioblastoma (GBM), a malignant and lethal tumor, remains a big threat to human health and life. Increasing explorations have confirmed that long noncoding RNAs are involved in the tumorigenesis and development of multiple cancers. Nevertheless,… read more here.
Keywords: cell proliferation; linc01579; mir 139; gbm ... See more keywords
Verification of candidate microRNA markers for parathyroid carcinoma
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DOI: 10.1007/s12020-018-1551-2
Abstract: PurposeParathyroid carcinoma (PCa) is a rare endocrine malignancy with poor prognosis and is often difficult to accurately diagnose both before and after surgery. Dysregulated microRNA (miRNA) levels have been identified in PCa using a limited… read more here.
Keywords: mir 139; mir 222; mir 30b; mir ... See more keywords
CircRNA circ-0038718 promotes hepatocellular carcinoma progression through sponging miR-139-3p.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.07.035
Abstract: Hepatocellular Carcinoma (HCC) is the main histological subtype of liver malignancy with poor prognosis. A growing body of evidence showed that Circular RNAs (circRNAs) are related to HCC tumorigenesis and progression. In this study, we… read more here.
Keywords: hepatocellular carcinoma; mir 139; hcc; circ 0038718 ... See more keywords
Porcine acellular dermal matrix accelerates wound healing through miR-124-3p.1 and miR-139-5p.
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DOI: 10.1016/j.jcyt.2020.04.042
Abstract: BACKGROUND AIMS Cutaneous wound management is a major health problem and imposes a huge economic burden worldwide. Previous studies have demonstrated that wound healing is a highly coordinated process including epithelialization, angiogenesis, remodeling and scarring.… read more here.
Keywords: wound healing; mir 139; 124 mir; porcine ... See more keywords
The miR-139-5p/peripheral myelin protein 22 axis modulates TGF-β-induced hepatic stellate cell activation and CCl4-induced hepatic fibrosis in mice.
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DOI: 10.1016/j.lfs.2021.119294
Abstract: Hepatic stellate cells (HSCs) are the major source of extracellular matrix (ECM)-producing myofibroblasts. When activated by multiple injuries, HSCs become proliferative, contractile, inflammatory and chemotactic and are characterized by enhanced ECM production, which plays a… read more here.
Keywords: mir 139; pmp22; tgf induced; activation ... See more keywords
Decreased lipid metabolism but increased FA biosynthesis are coupled with changes in liver microRNAs in obese subjects with NAFLD
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DOI: 10.1038/ijo.2017.21
Abstract: Background/Objective:Many controversies regarding the association of liver miRNAs with obesity and nonalcoholic fatty liver diseases (NAFLD) call for additional validations. This study sought to investigate variations in genes and hepatic miRNAs in a sample of… read more here.
Keywords: mir 139; biosynthesis; mir 30b; metabolism ... See more keywords
miR-125a, miR-139 and miR-324 contribute to Urocortin protection against myocardial ischemia-reperfusion injury
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DOI: 10.1038/s41598-017-09198-x
Abstract: Urocortin 1 and 2 (Ucn-1 and Ucn-2) have established protective actions against myocardial ischemia-reperfusion (I/R) injuries. However, little is known about their role in posttranscriptional regulation in the process of cardioprotection. Herein, we investigated whether… read more here.
Keywords: mir 139; mir; reperfusion; 125a mir ... See more keywords