Effect of microRNA-145 on proliferation and apoptosis of human non-small cell lung cancer A549 cells by regulating mTOR signaling pathway.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of cellular biochemistry"
DOI: 10.1002/jcb.26629
Abstract: Our study aims to explore the impact of microRNA-145 (miR-145) on proliferation and apoptosis of non-small cell lung cancer (NSCLC) cells by modulating mTOR signaling pathway. Paired NSCLC and adjacent normal tissues were obtained from… read more here.
Keywords: mir 145; mtor signaling; proliferation; signaling pathway ... See more keywords
Long non‐coding RNA SNHG14 contributes to gastric cancer development through targeting miR‐145/SOX9 axis
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.26889
Abstract: This study aimed to elucidate the roles of long non‐coding RNA SNHG14 in gastric cancer development. LncRNA SNHG14 was markedly up‐regulated in gastric cancer tissues and cells. Knockdown of SNHG14 significantly inhibited SGC‐7901 cell viability,… read more here.
Keywords: 145 sox9; mir 145; gastric cancer; snhg14 ... See more keywords
LncRNA Erbb4‐IR promotes esophageal squamous cell carcinoma (ESCC) by downregulating miR‐145
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.29023
Abstract: Erbb4‐IR is a recently identified lncRNA with pivotal functions in renal injury. The present study investigated the roles of Erbb4‐IR in esophageal squamous cell carcinoma (ESCC). It was observed that Erbb4‐IR was upregulated in tumor… read more here.
Keywords: esophageal squamous; mir 145; cell carcinoma; squamous cell ... See more keywords
MiR‐145 Regulates Lipogenesis in Goat Mammary Cells Via Targeting INSIG1 and Epigenetic Regulation of Lipid‐Related Genes
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.25499
Abstract: MicroRNAs (miRNAs) are noncoding RNA molecules that regulate gene expression at the post‐transcriptional level to cause translational repression or degradation of targets. The profiles of miRNAs across stages of lactation in small ruminant species such… read more here.
Keywords: 145 regulates; mir 145; goat mammary; mammary gland ... See more keywords
miR‐145‐5p affects the differentiation of gastric cancer by targeting KLF5 directly
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.27525
Abstract: Krüppel‐like factor 5 (KLF5) takes part in the pathologic processes of many types of cancer; however, its expression and roles in the biological behavior of gastric cancer remain unknown. TargetScan suggested that miR‐145‐5p is the… read more here.
Keywords: mir 145; gastric cancer; differentiation; expression ... See more keywords
Identification of miR‐145‐5p‐Centered Competing Endogenous RNA Network in Laryngeal Squamous Cell Carcinoma
Sign Up to like & getrecommendations! Published in 2019 at "PROTEOMICS"
DOI: 10.1002/pmic.201900020
Abstract: This study intends to investigate the transcriptional regulatory role of miR‐145‐5p in laryngeal squamous cell carcinoma (LSCC). LSCC cell line TU‐177 is transfected with miR‐145‐5p mimics, generating miR‐145‐5p‐overexpression LSCC cells. Whole transcriptome microarrays are used… read more here.
Keywords: cell; mir 145; cell carcinoma; squamous cell ... See more keywords
miR-145-5p targets paxillin to attenuate angiotensin II-induced pathological cardiac hypertrophy via downregulation of Rac 1, pJNK, p-c-Jun, NFATc3, ANP and by Sirt-1 upregulation.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular and cellular biochemistry"
DOI: 10.1007/s11010-021-04100-w
Abstract: Pathological cardiac hypertrophy is associated with many diseases including hypertension. Recent studies have identified important roles for microRNAs (miRNAs) in many cardiac pathophysiological processes, including the regulation of cardiomyocyte hypertrophy. However, the role of miR-145-5p… read more here.
Keywords: cardiac hypertrophy; mir 145; nfatc3 anp; jun nfatc3 ... See more keywords
Analysis of changes in the expression pattern of miR-326 and miR-145 during storage of platelet concentrate in blood bank condition and its relationship with some markers of platelet quality
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Thrombosis and Thrombolysis"
DOI: 10.1007/s11239-021-02467-7
Abstract: Platelet concentrates (PC) are affected by biochemical, morphological and functional changes during storage that are named platelet storage lesion (PSL) can decrease the survival and quality of platelets. The potential role and importance of the… read more here.
Keywords: storage; quality; mir 145; mir 326 ... See more keywords
Expression of MicroRNAs miR-145, miR-181c, miR-199a and miR-1183 in the Blood and Hippocampus of Patients with Mesial Temporal Lobe Epilepsy
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Molecular Neuroscience"
DOI: 10.1007/s12031-019-01386-w
Abstract: The aim of this study was to analyze the expression profiles of the microRNAs (miRNAs) miR-145, miR-181c, miR-199a and miR-1183 in the hippocampus and blood of patients with mesial temporal lobe epilepsy with hippocampal sclerosis… read more here.
Keywords: hippocampus; mir 145; mir; 145 mir ... See more keywords
microRNA-145 mediates xylosyltransferase-I induction in myofibroblasts via suppression of transcription factor KLF4.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.12.120
Abstract: Remodelling of the extracellular matrix by myofibroblasts is crucial for wound repair, but if deregulated, it might contribute to the development of fibrosis. Fibroblast-to-myofibroblast differentiation is promoted by aberrant microRNA-145-5p (miR-145) expression in response to… read more here.
Keywords: transcription; mir 145; microrna 145; expression ... See more keywords
miR-145 micelles mitigate atherosclerosis by modulating vascular smooth muscle cell phenotype.
Sign Up to like & getrecommendations! Published in 2021 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2021.120810
Abstract: In atherosclerosis, resident vascular smooth muscle cells (VSMCs) in the blood vessels become highly plastic and undergo phenotypic switching from the quiescent, contractile phenotype to the migratory and proliferative, synthetic phenotype. Additionally, recent VSMC lineage-tracing… read more here.
Keywords: phenotype; mir 145; cell; atherosclerosis ... See more keywords