miR-146b Regulates Cell Proliferation and Apoptosis in Gastric Cancer by Targeting PTP1B
Sign Up to like & getrecommendations! Published in 2019 at "Digestive Diseases and Sciences"
DOI: 10.1007/s10620-019-05771-8
Abstract: Background/Aims The purpose of this study is to explore the inhibition or activation effects of microRNA-146 B on the expression of PTP1B in gastric cancer cells. Methods The expressions of PTP1B and miR-146b in gastric… read more here.
Keywords: apoptosis; gastric cancer; ptp1b; expression ... See more keywords
LncRNA NEAT1 Regulates Infantile Pneumonia by Sponging miR-146b
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Biotechnology"
DOI: 10.1007/s12033-021-00331-w
Abstract: This study designed to investigate the potential role of lncRNA NEAT1/miR-146b in infantile pneumonia. In this study, 58 children with pneumonia and 58 healthy children collected for routine examination from December 2016 to January 2019.… read more here.
Keywords: neat1 regulates; mir 146b; infantile pneumonia; lncrna neat1 ... See more keywords
Are women more susceptible to renal dysfunction than men?
Sign Up to like & getrecommendations! Published in 2019 at "Kidney international"
DOI: 10.1016/j.kint.2019.08.030
Abstract: Is there any difference in sensitivity to kidney function between men and women? Paterson et al. have focused on sex differences in chronic kidney disease. Surprisingly, their experimental results show that only one microRNA, miR-146b-5p, affected… read more here.
Keywords: women susceptible; renal dysfunction; susceptible renal; men women ... See more keywords
Dual inhibition of EGFR and IL-6-STAT3 signalling by miR-146b: a potential targeted therapy for epithelial ovarian cancer
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Enzyme Inhibition and Medicinal Chemistry"
DOI: 10.1080/14756366.2021.1963240
Abstract: Abstract Epidermal growth factor receptor (EGFR) signalling and the interleukin-6 (IL-6)/signal transducer and activator of transcription 3 (STAT3) are aberrantly activated in ovarian cancer. However, inhibition of EGFR signalling in ovarian cancer patients resulted in… read more here.
Keywords: egfr; inhibition; stat3; ovarian cancer ... See more keywords
Circ_0014235 confers Gefitinib resistance and malignant behaviors in non-small cell lung cancer resistant to Gefitinib by governing the miR-146b-5p/YAP/PD-L1 pathway
Sign Up to like & getrecommendations! Published in 2021 at "Cell Cycle"
DOI: 10.1080/15384101.2021.2009986
Abstract: ABSTRACT Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs), such as Gefitinib, have been recommended as the first-line treatment reagent for advanced EGFR-mutant non-small cell lung cancer (NSCLC). However, the mechanisms of drug resistance development… read more here.
Keywords: circ 0014235; yap; mir 146b; cell ... See more keywords
MicroRNA-146b-3p regulates the dysfunction of vascular smooth muscle cells via repressing phosphoinositide-3 kinase catalytic subunit gamma.
Sign Up to like & getrecommendations! Published in 2021 at "Bioengineered"
DOI: 10.1080/21655979.2021.1937904
Abstract: MicroRNAs are crucial regulators in the phenotype switch of vascular smooth muscle cells (VSMCs). Nonetheless, the role of miR-146b-3p in VSMCs remains unclear. In the present study, platelet-derived growth factor-BB (PDGF-BB) at different concentrations was… read more here.
Keywords: pik3cg; vsmcs; vascular smooth; muscle cells ... See more keywords
MiR-146b protects against the inflammation injury in pediatric pneumonia through MyD88/NF-κB signaling pathway
Sign Up to like & getrecommendations! Published in 2019 at "Infectious Diseases"
DOI: 10.1080/23744235.2019.1671987
Abstract: Abstract Background: Pneumonia is a common respiratory disease worldwide that can be prevented and treated. However, it is considered to be the leading cause of children death. The present study was aimed to explore the… read more here.
Keywords: pediatric pneumonia; inflammation injury; injury pediatric; mir 146b ... See more keywords
Lnc-AL445665.1-4 may be involved in the development of multiple uterine leiomyoma through interacting with miR-146b-5p
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Oncology"
DOI: 10.1093/annonc/mdz426.031
Abstract: Abstract Background The clinical behaviors and cytogenetics of solitary uterine leiomyomas (SUL) and multiple uterine leiomyomas (MUL) vary. Our previous study demonstrated that miR-146b-5p played important roles in the development of SUL and MUL. Long… read more here.
Keywords: multiple uterine; mir 146b; mul; lnc al445665 ... See more keywords
Involvement of a novel circularRNA, hsa_circ_0000520, attenuates tumorigenesis of cervical cancer cell through competitively binding with miR‐146b‐3p
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.15414
Abstract: The implication of circular RNAs (circRNAs) in the pathogenesis of human cervical cancer (CC) has been demonstrated by numerous of researches, nevertheless, the whole regulatory network of circRNAs in CC remains unclear. In the present… read more here.
Keywords: cervical cancer; circ 0000520; mir 146b; cell ... See more keywords
Specific Autoantibodies and Clinical Phenotypes Correlate with the Aberrant Expression of Immune-Related MicroRNAs in Dermatomyositis
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Immunology Research"
DOI: 10.1155/2019/2927061
Abstract: Aims The serum concentrations of miRNAs, miR-23a-3p, miR-23b-3p, miR-146a-5p, miR-146b-5p, and miR-150-5p, were shown to be associated with the immune and inflammatory progressions. We assessed the expressions of these five miRNAs in association with clinical… read more here.
Keywords: immune; mir 146a; mir 23b; mir ... See more keywords
Inflammatory Factors Induce Thrombosis through the miR-146b-3p/p38MAPK/COX-2 Pathway
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DOI: 10.1155/2020/8718321
Abstract: Objective Inflammatory responses play important roles in the pathogenesis of atherosclerosis. The purpose of this study was to investigate the relationship between microRNA-146b-3p (miR-146b-3p) and inflammatory factors in thrombosis. Method THP-1 cells were cultured in… read more here.
Keywords: mir 146b; expression; p38mapk cox;