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   Articles with "mir 148a" as a keyword



miR‐148a weaves its thread into the plasma cell fate

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recommendations! Published in 2021 at "European Journal of Immunology"

DOI: 10.1002/eji.202149240

Abstract: The plasma cells (PC) are characterized by their rarity, their formidable capacity to continuously secrete massive amounts of antibodies and the potential to live through the whole life span of the organism that houses them.… read more here.

Keywords: weaves thread; plasma; mir 148a; 148a weaves ... See more keywords

MiR-148a-3p/SIRT7 axis promotes glioma progression and regulates temozolomide chemosensitivity

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recommendations! Published in 2025 at "Journal of Neuro-Oncology"

DOI: 10.1007/s11060-025-05303-7

Abstract: Glioma is a highly malignant primary neoplasm of the central nervous system. Temozolomide (TMZ) is the first-line chemotherapeutic drug for glioma, commonly employed in conjunction with radiotherapy to improve overall patient outcomes, but the resistance… read more here.

Keywords: glioma progression; sirt7; mir 148a; axis ... See more keywords

microRNA-148a-3p enhances the effects of sevoflurane on hepatocellular carcinoma cell progression via ROCK1 repression.

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recommendations! Published in 2021 at "Cellular signalling"

DOI: 10.1016/j.cellsig.2021.109982

Abstract: BACKGROUND Sevoflurane (SEVO) inactivates the aggressiveness of hepatocellular carcinoma (HCC) cells by mediating microRNAs (miRNAs). Hence, we delved into the functional role of miR-148a-3p mediated by SEVO in HCC. METHODS Liver cells (L02) and HCC… read more here.

Keywords: hcclm3 huh7; mir 148a; rock1; cell progression ... See more keywords

Metformin exhibits its therapeutic effect in the treatment of pre-eclampsia via modulating the Met/H19/miR-148a-5p/P28 and Met/H19/miR-216-3p/EBI3 signaling pathways.

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recommendations! Published in 2019 at "International immunopharmacology"

DOI: 10.1016/j.intimp.2019.105693

Abstract: Metformin (Met) has been found to modify the methylation of H19 and to alter its expression. In addition, IL-27, one of the downstream factors in the H19 signaling pathway, plays an important role in the… read more here.

Keywords: met h19; mir 148a; mir; h19 mir ... See more keywords

LncRNA SNHG4 promotes the increased growth of endometrial tissue outside the uterine cavity via regulating c-Met mediated by miR-148a-3p

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recommendations! Published in 2020 at "Molecular and Cellular Endocrinology"

DOI: 10.1016/j.mce.2020.110887

Abstract: Long noncoding RNAs (lncRNAs) modulate endometriosis. The current study investigated the mechanisms and effects of SNHG4 on endometriosis. The qRT-PCR was conducted to examine the miR-148a-3p and SNHG4 expressions in endometriosis tissues. The 5-ethynyl-2'-deoxyuridine incorporation… read more here.

Keywords: endometriosis; mir 148a; lncrna snhg4; growth ... See more keywords

LINC00346 regulates glycolysis by modulation of glucose transporter 1 in breast cancer cells.

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recommendations! Published in 2020 at "Molecular and cellular probes"

DOI: 10.1016/j.mcp.2020.101667

Abstract: Most cancer cells preferentially metabolize glucose by glycolysis rather than oxidative phosphorylation to proliferate efficiently. LncRNAs have been proposed as crucial regulators in pathophysiological processes including cell growth, apoptosis and glucose metabolism. However, little is… read more here.

Keywords: glycolysis; mir 148a; breast cancer; cancer cells ... See more keywords
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Aberrant expression of miR-148a-3p in Alzheimer’s disease and its protective role against amyloid-β induced neurotoxicity

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recommendations! Published in 2021 at "Neuroscience Letters"

DOI: 10.1016/j.neulet.2021.135953

Abstract: OBJECTIVE The current study investigated the expression change and clinical value of miR-148a-3p in AD patients, and further examined the role of miR-148a-3p in Aβ-induced neurotoxicity in SH-SY5Y cells. MATERIAL AND METHODS qRT-PCR was used… read more here.

Keywords: mir 148a; induced neurotoxicity; expression; role ... See more keywords

Curcumin Upregulates miR-148a to Increase the Chemosensitivity of CD44-Positive Prostate Cancer Stem Cells to Paclitaxel Through Targeting the MSK1/IRS1 axis.

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recommendations! Published in 2022 at "Drug research"

DOI: 10.1055/a-1867-4805

Abstract: BACKGROUND In men, prostate cancer (PC) is the second most common cause of cancer-related death. However, paclitaxel resistance is a major challenge in advanced PC. Curcumin, a natural antioxidant, has been demonstrated to have cytotoxic… read more here.

Keywords: prostate cancer; cancer stem; mir 148a; curcumin paclitaxel ... See more keywords

Functional and mechanistic study of miR-148a-3p as a novel biomarker for type 2 diabetic peripheral neuropathy.

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recommendations! Published in 2025 at "Neurological research"

DOI: 10.1080/01616412.2025.2571981

Abstract: BACKGROUND Type 2 diabetic peripheral neuropathy (T2DM-DPN) not only raises amputation risk but also strains healthcare resources, making the identification of diagnostic biomarkers crucial for early intervention and targeted treatment. AIM The research sought to… read more here.

Keywords: type diabetic; mir 148a; diabetic peripheral; t2dm dpn ... See more keywords

Long non-coding RNA SNHG4 promotes cervical cancer progression through regulating c-Met via targeting miR-148a-3p

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recommendations! Published in 2019 at "Cell Cycle"

DOI: 10.1080/15384101.2019.1674071

Abstract: ABSTRACT Long non-coding RNA (lncRNA) SNHG4 has been shown to be associated with the development of a variety of cancers. The purpose of this study was to investigate the effect of SNHG4 on cervical cancer… read more here.

Keywords: mir 148a; long non; non coding; coding rna ... See more keywords

LncRNA MEG3 Suppresses Prostate Cancer Progression by Mediating Macrophage Polarization via the miR-148a-3p/ARRDC3 Signaling Axis.

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recommendations! Published in 2025 at "Carcinogenesis"

DOI: 10.1093/carcin/bgaf009

Abstract: Long-chain non-coding RNA (LncRNA) MEG3 significantly influences tumor microenvironment (TME) dynamics and macrophage polarization. However, its specific involvement in prostate cancer (PCa) progression remains unclear. MEG3 exhibited low expression in PCa, and immune infiltration analysis… read more here.

Keywords: macrophage polarization; arrdc3; meg3; mir 148a ... See more keywords