Articles with "mir 148a" as a keyword



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miR‐148a weaves its thread into the plasma cell fate

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Published in 2021 at "European Journal of Immunology"

DOI: 10.1002/eji.202149240

Abstract: The plasma cells (PC) are characterized by their rarity, their formidable capacity to continuously secrete massive amounts of antibodies and the potential to live through the whole life span of the organism that houses them.… read more here.

Keywords: weaves thread; plasma; mir 148a; 148a weaves ... See more keywords
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microRNA-148a-3p enhances the effects of sevoflurane on hepatocellular carcinoma cell progression via ROCK1 repression.

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Published in 2021 at "Cellular signalling"

DOI: 10.1016/j.cellsig.2021.109982

Abstract: BACKGROUND Sevoflurane (SEVO) inactivates the aggressiveness of hepatocellular carcinoma (HCC) cells by mediating microRNAs (miRNAs). Hence, we delved into the functional role of miR-148a-3p mediated by SEVO in HCC. METHODS Liver cells (L02) and HCC… read more here.

Keywords: hcclm3 huh7; mir 148a; rock1; cell progression ... See more keywords
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Metformin exhibits its therapeutic effect in the treatment of pre-eclampsia via modulating the Met/H19/miR-148a-5p/P28 and Met/H19/miR-216-3p/EBI3 signaling pathways.

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Published in 2019 at "International immunopharmacology"

DOI: 10.1016/j.intimp.2019.105693

Abstract: Metformin (Met) has been found to modify the methylation of H19 and to alter its expression. In addition, IL-27, one of the downstream factors in the H19 signaling pathway, plays an important role in the… read more here.

Keywords: met h19; mir 148a; mir; h19 mir ... See more keywords
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LncRNA SNHG4 promotes the increased growth of endometrial tissue outside the uterine cavity via regulating c-Met mediated by miR-148a-3p

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Published in 2020 at "Molecular and Cellular Endocrinology"

DOI: 10.1016/j.mce.2020.110887

Abstract: Long noncoding RNAs (lncRNAs) modulate endometriosis. The current study investigated the mechanisms and effects of SNHG4 on endometriosis. The qRT-PCR was conducted to examine the miR-148a-3p and SNHG4 expressions in endometriosis tissues. The 5-ethynyl-2'-deoxyuridine incorporation… read more here.

Keywords: endometriosis; mir 148a; lncrna snhg4; growth ... See more keywords
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LINC00346 regulates glycolysis by modulation of glucose transporter 1 in breast cancer cells.

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Published in 2020 at "Molecular and cellular probes"

DOI: 10.1016/j.mcp.2020.101667

Abstract: Most cancer cells preferentially metabolize glucose by glycolysis rather than oxidative phosphorylation to proliferate efficiently. LncRNAs have been proposed as crucial regulators in pathophysiological processes including cell growth, apoptosis and glucose metabolism. However, little is… read more here.

Keywords: glycolysis; mir 148a; breast cancer; cancer cells ... See more keywords
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Aberrant expression of miR-148a-3p in Alzheimer’s disease and its protective role against amyloid-β induced neurotoxicity

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Published in 2021 at "Neuroscience Letters"

DOI: 10.1016/j.neulet.2021.135953

Abstract: OBJECTIVE The current study investigated the expression change and clinical value of miR-148a-3p in AD patients, and further examined the role of miR-148a-3p in Aβ-induced neurotoxicity in SH-SY5Y cells. MATERIAL AND METHODS qRT-PCR was used… read more here.

Keywords: mir 148a; induced neurotoxicity; expression; role ... See more keywords
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Curcumin Upregulates miR-148a to Increase the Chemosensitivity of CD44-Positive Prostate Cancer Stem Cells to Paclitaxel Through Targeting the MSK1/IRS1 axis.

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Published in 2022 at "Drug research"

DOI: 10.1055/a-1867-4805

Abstract: BACKGROUND In men, prostate cancer (PC) is the second most common cause of cancer-related death. However, paclitaxel resistance is a major challenge in advanced PC. Curcumin, a natural antioxidant, has been demonstrated to have cytotoxic… read more here.

Keywords: prostate cancer; cancer stem; mir 148a; curcumin paclitaxel ... See more keywords
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Long non-coding RNA SNHG4 promotes cervical cancer progression through regulating c-Met via targeting miR-148a-3p

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Published in 2019 at "Cell Cycle"

DOI: 10.1080/15384101.2019.1674071

Abstract: ABSTRACT Long non-coding RNA (lncRNA) SNHG4 has been shown to be associated with the development of a variety of cancers. The purpose of this study was to investigate the effect of SNHG4 on cervical cancer… read more here.

Keywords: mir 148a; long non; non coding; coding rna ... See more keywords
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microRNA‐148a‐3p in extracellular vesicles derived from bone marrow mesenchymal stem cells suppresses SMURF1 to prevent osteonecrosis of femoral head

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Published in 2020 at "Journal of Cellular and Molecular Medicine"

DOI: 10.1111/jcmm.15766

Abstract: Extracellular vesicle (EV)‐associated microRNAs (miRNAs) have been found as the important biomarkers participating in the development of osteonecrosis of the femoral head (ONFH). Consequently, this study sought to examine the underlying mechanism of bone marrow… read more here.

Keywords: 148a mimic; onfh rats; mir 148a; mir ... See more keywords
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Alcohol dysregulates miR-148a in hepatocytes through FoxO1, facilitating pyroptosis via TXNIP overexpression

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Published in 2018 at "Gut"

DOI: 10.1136/gutjnl-2017-315123

Abstract: Objective Alcoholic liver disease (ALD) is a leading cause of death among chronic liver diseases. However, its pathogenesis has not been completely established. MicroRNAs (miRNAs) are key contributors to liver diseases progression. This study investigated… read more here.

Keywords: txnip overexpression; mir 148a; pyroptosis; hepatocytes foxo1 ... See more keywords
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Human Papillomavirus 16 Oncoproteins Downregulate the Expression of miR-148a-3p, miR-190a-5p, and miR-199b-5p in Cervical Cancer

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Published in 2018 at "BioMed Research International"

DOI: 10.1155/2018/1942867

Abstract: Almost all cervical cancers are associated with human papillomavirus (HPV); however, the majority of women infected with this virus do not develop cervical cancer. Therefore, new markers are needed for reliable screening of cervical cancer,… read more here.

Keywords: mir 148a; mir; mir 190a; cervical cancer ... See more keywords