Combined serum miR‐29c and miR‐149 expression analysis as diagnostic genetic markers for colorectal cancer
Sign Up to like & getrecommendations! Published in 2020 at "Biotechnology and Applied Biochemistry"
DOI: 10.1002/bab.1986
Abstract: Circulating miRNAs gathered much interest in cancer research as noninvasive biomarkers. The aim of this study was to analyze the expression of miR‐29c and miR‐149 among colorectal cancer (CRC) patients and to explore their diagnostic… read more here.
Keywords: mir 149; mir; expression; cancer ... See more keywords
Long non‐coding RNA MALAT1 sponges miR‐149 to promote inflammatory responses of LPS‐induced acute lung injury by targeting MyD88
Sign Up to like & getrecommendations! Published in 2019 at "Cell Biology International"
DOI: 10.1002/cbin.11235
Abstract: Acute lung injury (ALI) caused by sepsis occurs early and the condition is severe, and is also an important reason for accelerating the death of patients. Increasing evidence has identified long non‐coding RNA (lncRNA) metastasis… read more here.
Keywords: lung injury; lps induced; mir 149; malat1 ... See more keywords
CircRNA casein kinase 1 gamma 1 (circ‐CSNK1G1) plays carcinogenic effects in thyroid cancer by acting as miR‐149‐5p sponge and relieving the suppression of miR‐149‐5p on mitogen‐activated protein kinase 1 (MAPK1)
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24188
Abstract: The initiation and development of thyroid cancer may be associated with the deregulation of circular RNAs (circRNAs). The purpose of this work was to explore the role of circRNA casein kinase 1 gamma 1 (circ‐CSNK1G1)… read more here.
Keywords: mir 149; thyroid cancer; casein kinase; circrna casein ... See more keywords
miR-149 promotes human osteocarcinoma progression via targeting bone morphogenetic protein 9 (BMP9)
Sign Up to like & getrecommendations! Published in 2017 at "Biotechnology Letters"
DOI: 10.1007/s10529-017-2445-8
Abstract: ObjectivesTo investigate the roles of miR-149 in the progression of human osteosarcoma (OS).ResultsmiR-149 level was upregulated in tissues from OS patients more than in normal subjects. Cell proliferation and apoptosis assays revealed that miR-149 increased… read more here.
Keywords: mg63 cells; mir 149; protein bmp9; bone morphogenetic ... See more keywords
miR-140-5p/miR-149 Affects Chondrocyte Proliferation, Apoptosis, and Autophagy by Targeting FUT1 in Osteoarthritis
Sign Up to like & getrecommendations! Published in 2018 at "Inflammation"
DOI: 10.1007/s10753-018-0750-6
Abstract: Osteoarthritis (OA), the most prevalent chronic and degenerative joint disease, is characterized by articular cartilage degradation and chondrocyte injury. Increased cell apoptosis and defective cell autophagy in chondrocytes are a feature of degenerative cartilage. MicroRNAs… read more here.
Keywords: mir 149; mir; proliferation; 140 mir ... See more keywords
LINC00472 regulates vascular smooth muscle cell migration and proliferation via regulating miR-149-3p
Sign Up to like & getrecommendations! Published in 2020 at "Environmental Science and Pollution Research"
DOI: 10.1007/s11356-020-10761-9
Abstract: LncRNAs are one group of gene modulators functioning via several mechanisms in pathological and physiological conditions. We noted that LINC00472 expression level is elevated in atherosclerotic coronary tissues compared with normal coronary artery samples. LINC00472… read more here.
Keywords: expression; migration proliferation; linc00472; mir 149 ... See more keywords
Downregulating circRNA_0044516 Inhibits Cell Proliferation in Gastric Cancer Through miR-149/Wnt1/β-catenin Pathway
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Gastrointestinal Surgery"
DOI: 10.1007/s11605-020-04834-w
Abstract: Circular RNAs (circRNAs) play important roles in the progression of gastric cancer (GC). The Wnt1/β-catenin pathway can promote the proliferation of GC cells. This study aimed to explore whether circRNA_0044516 can regulate the proliferation of… read more here.
Keywords: mir 149; proliferation; circrna 0044516; wnt1 catenin ... See more keywords
Melatonin suppresses ischemia-induced fibrosis by regulating miR-149.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.02.090
Abstract: Ischemic injury is a major risk factor for fibrosis. However, the precise mechanisms by which fibrosis is regulated and induced under ischemic oxidative stress conditions are unknown. To address this, we investigated the effect of… read more here.
Keywords: fibrosis; mir 149; ischemia induced; melatonin ... See more keywords
Suppression of circular RNA circDHCR24 alleviates aortic smooth muscle cell proliferation and migration by targeting miR-149-5p/MMP9 axis.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.06.067
Abstract: Circular RNAs (circRNAs) are involved in many courses of atherosclerosis and coronary artery disease (CHD). However, the role and effect of circRNAs in vascular restenosis after PCI remains unclear. Human aortic vascular smooth muscle cell… read more here.
Keywords: proliferation migration; circdhcr24; cell; mir 149 ... See more keywords
The JAK Inhibitor Tofacitinib Inhibits Structural Damage in Osteoarthritis by Modulating JAK1/TNF-alpha/IL-6 Signaling Through Mir-149-5p.
Sign Up to like & getrecommendations! Published in 2021 at "Bone"
DOI: 10.1016/j.bone.2021.116024
Abstract: BACKGROUND Osteoarthritis (OA), a common articular bone degenerative disease, is exacerbated by proinflammatory cytokine signaling. Mounting evidence suggests that epigenetic modifiers, namely microRNAs (miRs), are dysregulated in articular chondrocytes (ACs) during OA. METHODS An initial… read more here.
Keywords: tofacitinib; jak1 tnf; expression; mir 149 ... See more keywords
Functional miR-146a, miR-149, miR-196a2 and miR-499 polymorphisms and the susceptibility to hepatocellular carcinoma: An updated meta-analysis.
Sign Up to like & getrecommendations! Published in 2017 at "Clinics and research in hepatology and gastroenterology"
DOI: 10.1016/j.clinre.2017.03.005
Abstract: OBJECTIVE Single nucleotide polymorphisms of miRNAs play important roles in the pathogenesis of hepatocellular carcinoma (HCC). To evaluate the association between four common miRNAs (miR-146a rs2910164; miR-149 rs2292832; miR-196a2 rs11614913 and miR-499 rs3746444) and HCC… read more here.
Keywords: mir 196a2; hcc; mir 149; mir 146a ... See more keywords