Articles with "mir 154" as a keyword



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Circ_101064 regulates the proliferation, invasion and migration of glioma cells through miR-154-5p/ PIWIL1 axis.

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Published in 2020 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2019.12.096

Abstract: This study aimed to investigate the effects of Circ_101064 on glioma cell proliferation, invasion, migration and explore the underlying mechanisms. The expression levels of Circ_101064 in glioma/para-carcinoma tissues and glioma cells were analyzed using RT-qPCR.… read more here.

Keywords: invasion migration; circ 101064; mir 154; glioma ... See more keywords

MiRNA-154-5p inhibits cell proliferation and metastasis by targeting PIWIL1 in glioblastoma

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Published in 2017 at "Brain Research"

DOI: 10.1016/j.brainres.2017.08.014

Abstract: MicroRNAs (miRNAs) play a critical role in glioblastoma initiation and progression. PIWIL1, a human homolog of the PIWI family, has a critical effect on glioblastoma progression. In present study, we found that the expression of… read more here.

Keywords: targeting piwil1; mir 154; glioblastoma; proliferation metastasis ... See more keywords

miR-154-3p and miR-487-3p synergistically modulate RHOA signaling in the carcinogenesis of thyroid cancer

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Published in 2019 at "Bioscience Reports"

DOI: 10.1042/bsr20193158

Abstract: Abstract Background: miRs family members are often thought to have extensively overlapping targets and synergistically to modulate target gene expression via post-transcriptional repression. The present study was to determine whether miR-154-3p and miR-487-3p synergistically collaborated… read more here.

Keywords: thyroid cancer; mir 154; rhoa; mir 487 ... See more keywords

miR-154-5p Affects the TGFβ1/Smad3 Pathway on the Fibrosis of Diabetic Kidney Disease via Binding E3 Ubiquitin Ligase Smurf1

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Published in 2022 at "Oxidative Medicine and Cellular Longevity"

DOI: 10.1155/2022/7502632

Abstract: Aim The study is aimed at verifying miR-154-5p and Smurf1 combination in glomerular mesangial cells regulating TGFβ1/Smad3 pathway-related protein ubiquitination in the model of diabetic rats renal tissues, primary mesangial cells, and cell lines. Methods… read more here.

Keywords: tgf smad3; smurf1; mir 154; diabetic kidney ... See more keywords

MiR-154 controls branching morphogenesis and alveologenesis in lung development involving Tgf-β signaling

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Published in 2017 at "European Respiratory Journal"

DOI: 10.1183/1393003.congress-2017.oa3229

Abstract: Background: MiR-154 is abundant in neonatal lungs. Experimental evidence for a direct effect of miR-154 on lung development is still lacking. Aims and methods: We aim to investigate the effect of miR-154 by using an… read more here.

Keywords: morphogenesis alveologenesis; branching morphogenesis; mir 154; lung development ... See more keywords

Influence of MiR-154 on myocardial apoptosis in rats with acute myocardial infarction through Wnt/β-catenin signaling pathway.

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Published in 2019 at "European review for medical and pharmacological sciences"

DOI: 10.26355/eurrev_201901_16896

Abstract: OBJECTIVE To explore the influence of micro ribonucleic acid (miR)-154 on myocardial apoptosis in rats with acute myocardial infarction (AMI), and to analyze whether Wnt/β-catenin signaling pathway was involved in the regulation. MATERIALS AND METHODS… read more here.

Keywords: expression level; 154 myocardial; mir 154; group ... See more keywords

Correlation Between Serum miR-154-5p and Osteocalcin in Males and Postmenopausal Females of Type 2 Diabetes With Different Urinary Albumin Creatinine Ratios

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Published in 2019 at "Frontiers in Endocrinology"

DOI: 10.3389/fendo.2019.00542

Abstract: Purpose: To investigate the serum levels of miR-154-5p, osteocalcin (OC), and other clinical parameters in male and post-menopausal female type 2 diabetes mellitus (T2DM) patients with different urinary albumin creatinine ratio (UACR) levels and to… read more here.

Keywords: mir 154; urinary albumin; 154 osteocalcin; correlation ... See more keywords
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MiR-154-5p-MCP1 Axis Regulates Allergic Inflammation by Mediating Cellular Interactions

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Published in 2021 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2021.663726

Abstract: In a previous study, we have demonstrated that p62, a selective receptor of autophagy, can regulate allergic inflammation. In the present study, microRNA array analysis showed that miR-154-5p was increased by antigen (DNP-HSA) in a… read more here.

Keywords: mir 154; allergic inflammation; cellular interactions; mcp1 ... See more keywords

Circulating exo-miR-154-5p regulates vascular dementia through endothelial progenitor cell-mediated angiogenesis

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Published in 2022 at "Frontiers in Cellular Neuroscience"

DOI: 10.3389/fncel.2022.881175

Abstract: Background Vascular dementia (VaD) mainly results from cerebral vascular lesions and tissue changes, which contribute to neurodegenerative processes. Effective therapeutic approaches to targeting angiogenesis may reduce mortality of VaD. Endothelial progenitor cells (EPCs) play a… read more here.

Keywords: vad; mir 154; mirna 154; dementia ... See more keywords

[Retracted] miR‑154 suppresses non‑small cell lung cancer growth in vitro and in vivo

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Published in 2023 at "Oncology Reports"

DOI: 10.3892/or.2023.8558

Abstract: Following the publication of the above paper, it was drawn to the Editors' attention by a concerned reader that certain of the western blotting data shown in Fig. 5 were strikingly similar to data appearing in… read more here.

Keywords: oncology; mir 154; 154 suppresses; oncology reports ... See more keywords
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A-to-I edited miR-154-p13-5p inhibited cell proliferation and migration and induced apoptosis by targeting LIX1L in the bladder cancer

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Published in 2024 at "Journal of Cancer"

DOI: 10.7150/jca.93388

Abstract: With the advancement of RNA sequencing technology, there has been a drive to uncover and elucidate the pivotal role of A-to-I RNA editing events in tumorigenesis. However, A-to-I miRNA editing events have been clearly identified… read more here.

Keywords: 154 p13; mir 154; bladder cancer;