The miR‐181 family: Wide‐ranging pathophysiological effects on cell fate and function
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30969
Abstract: MicroRNAs (miRNAs) are epigenetic regulators that can target and inhibit translation of multiple mRNAs within a given cell type. As such, a number of different pathways and networks may be modulated as a result. In… read more here.
Keywords: function; 181 homologs; mir 181; number ... See more keywords
MiR-181 family-specific behavior in different cancers: a meta-analysis view
Sign Up to like & getrecommendations! Published in 2017 at "Cancer and Metastasis Reviews"
DOI: 10.1007/s10555-017-9714-9
Abstract: The involvement of microRNAs in malignant transformation and cancer progression was previously grounded. The observations made by multiple published studies led to the conclusion that some of these small sequences could be eventually used as… read more here.
Keywords: cancer; mir 181; meta analysis; 181 family ... See more keywords
MiR-181 enhances proliferative and migratory potentials of retinal endothelial cells in diabetic retinopathy by targeting KLF6.
Sign Up to like & getrecommendations! Published in 2022 at "Current eye research"
DOI: 10.1080/02713683.2022.2039206
Abstract: PURPOSE We aimed to uncover the role of microRNA-181 (miR-181) in the disease onset of diabetic retinopathy (DR) and its underlying mechanism. METHODS MiR-181 levels in plasma and aqueous humor samples of non-proliferative diabetic retinopathy… read more here.
Keywords: mir 181; klf6; retinal endothelial; enhances proliferative ... See more keywords
Exosomal lncRNA-p21 derived from mesenchymal stem cells protects epithelial cells during LPS-induced acute lung injury by sponging miR-181.
Sign Up to like & getrecommendations! Published in 2021 at "Acta biochimica et biophysica Sinica"
DOI: 10.1093/abbs/gmab043
Abstract: Long noncoding RNAs (lncRNAs) act as essential regulators of various diseases. However, the functions of lncRNAs in sepsis-induced acute lung injury (SALI) remain unclear. Here, we found that lipopolysaccharide could upregulate lncRNA-p21 expression in mesenchymal… read more here.
Keywords: lncrna p21; mir 181; injury; induced acute ... See more keywords
Expressions of miR-155 and miR-181 and predictions of their structures and targets in pigs (Sus scrofa)
Sign Up to like & getrecommendations! Published in 2020 at "Veterinary World"
DOI: 10.14202/vetworld.2020.1667-1673
Abstract: Background and Aim: MicroRNAs (miRNAs) are responsible for gene expression control at the post-transcription level in many species. Several miRNAs are required in the regulation of immune responses, such as B-cell differentiation, T-cell receptor signaling… read more here.
Keywords: mir 181; mir 155; expressions mir; cells tissues ... See more keywords
MicroRNA-181 as a prognostic biomarker for survival in acute myeloid leukemia: a meta-analysis
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.19195
Abstract: Accumulating evidence has indicated that microRNA-181 (miR-181) is dysregulated in hematological malignancies, and associates with the clinical outcomes. However, the association of miR-181 expression levels with acute myeloid leukemia (AML) remains inconclusive, as publications from… read more here.
Keywords: mir 181; aml patients; microrna 181; analysis ... See more keywords
miR-200a-3p- and miR-181-5p-Mediated HOXB5 Upregulation Promotes HCC Progression by Transcriptional Activation of EGFR
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.822760
Abstract: Background Hepatocellular carcinoma (HCC) remains a worldwide burden. However, the mechanisms behind the malignant biological behavior of HCC remain unclear. The homeobox (HOX) family could act as either promoters or suppressors in different kinds of… read more here.
Keywords: hcc progression; mir 181; 200a mir; mir ... See more keywords
Chronic Variable Stress Induces Hepatic Fe(II) Deposition by Up-Regulating ZIP14 Expression via miR-181 Family Pathway in Rats
Sign Up to like & getrecommendations! Published in 2021 at "Biology"
DOI: 10.3390/biology10070653
Abstract: Simple Summary Modern intensive production methods attract accusations of poor animal welfare due to long-term exposure to stressors including high temperature, persistent humidity and overcrowding. Stress can be defined as any condition that threatens the… read more here.
Keywords: mir 181; stress; expression; iron ... See more keywords
Integrated Genomics Identifies miR-181/TFAM Pathway as a Critical Driver of Drug Resistance in Melanoma
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22041801
Abstract: MicroRNAs (miRNAs) are attractive therapeutic targets and promising candidates as molecular biomarkers for various therapy-resistant tumors. However, the association between miRNAs and drug resistance in melanoma remains to be elucidated. We used an integrative genomic… read more here.
Keywords: melanoma; resistance melanoma; mir 181; drug ... See more keywords
Evaluation of MiR-181a as a potential therapeutic target in osteoarthritis
Sign Up to like & getrecommendations! Published in 2017 at "Tropical Journal of Pharmaceutical Research"
DOI: 10.4314/tjpr.v16i5.14
Abstract: Purpose: To investigate microRNA-181 (miR-181) as a potential therapeutic target in osteoarthritis (OA). Methods: MiR-181 expression was evaluated in articular cartilage samples obtained from OA patients undergoing knee arthroplasty and non-OA (control) patients undergoing other… read more here.
Keywords: mir 181; target; potential therapeutic; mir 181a ... See more keywords