Articles with "mir 181b" as a keyword



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lncRNA CCAT1 Promotes Glioma Tumorigenesis by Sponging miR‐181b

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Published in 2017 at "Journal of Cellular Biochemistry"

DOI: 10.1002/jcb.26116

Abstract: Colon cancer‐associated transcript 1 (CCAT1), a long non‐coding RNA (lncRNA), is upregulated and has a vital role in the pathogenesis of numerous cancers. Recently, its high expression was found in glioma tissues. miR‐181b is downregulated… read more here.

Keywords: promotes glioma; ccat1; expression; ccat1 promotes ... See more keywords
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Inhibition of lncRNA MEG3 protects renal tubular from hypoxia‐induced kidney injury in acute renal allografts by regulating miR‐181b/TNF‐α signaling pathway

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Published in 2019 at "Journal of Cellular Biochemistry"

DOI: 10.1002/jcb.28553

Abstract: Early damage to transplanted organs initiates excess inflammation that deteriorates existing injury, which is a leading cause of graft loss. Long noncoding RNAs (lncRNAs) are recently thought to play a significant role in cellular homeostasis… read more here.

Keywords: tnf; tnf alpha; hypoxia induced; injury ... See more keywords
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Dysregulation of microRNA‐181b and TIMP3 is functionally involved in the pathogenesis of diabetic nephropathy

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Published in 2019 at "Journal of Cellular Physiology"

DOI: 10.1002/jcp.28536

Abstract: This study aimed to study the roleof microRNA (miR)‐181b and its target TIMP3 in the development of diabetic nephropathy (DMN) via inhibiting the apoptosis of mesangial cells. Real‐time polymerase chain reaction (RT‐PCR) was adopted to… read more here.

Keywords: timp3 mrna; 181b expression; timp3; diabetic nephropathy ... See more keywords
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MicroRNA-181b Inhibits Inflammatory Response and Reduces Myocardial Injury in Sepsis by Downregulating HMGB1.

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Published in 2021 at "Inflammation"

DOI: 10.1007/s10753-020-01411-w

Abstract: MicroRNAs (miRNAs) are short endogenous noncoding RNAs regulating protein translation. However, the specific mechanism by which miR-181b influences sepsis via high-mobility group box-1 protein (HMGB1) still remains unknown. Thus, the aim of this study is… read more here.

Keywords: hmgb1; sepsis; myocardial injury; mir 181b ... See more keywords
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MiR-181b modulates chemosensitivity of glioblastoma multiforme cells to temozolomide by targeting the epidermal growth factor receptor

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Published in 2017 at "Journal of Neuro-Oncology"

DOI: 10.1007/s11060-017-2463-3

Abstract: Temozolomide (TMZ) is a promising chemotherapeutic agent to treat Glioblastoma multiforme (GBM). However, resistance to TMZ develops quickly with a high frequency. The mechanisms underlying GBM cells’ resistance to TMZ are not fully understood. MicroRNAs… read more here.

Keywords: gbm; glioblastoma multiforme; growth factor; tmz ... See more keywords
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CircRNA Profiling Reveals an Abundant circBDP1 that Regulates Bovine Fat Development by Sponging miR-181b/miR-204 Targeting Sirt1/TRARG1.

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Published in 2022 at "Journal of agricultural and food chemistry"

DOI: 10.1021/acs.jafc.2c05939

Abstract: The proliferation and differentiation of preadipocytes is an important factor determining bovine fat development, which is closely related to the feed conversion ratio, carcass traits, and beef quality. The purpose of this study was to… read more here.

Keywords: mir 204; mir 181b; fat development; bovine fat ... See more keywords
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Identification and characterization of microRNAs, especially gga-miR-181b-5p, in chicken macrophages associated with avian pathogenic E. coli infection

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Published in 2023 at "Avian Pathology"

DOI: 10.1080/03079457.2023.2181146

Abstract: ABSTRACT Avian pathogenic E. coli (APEC) is a common pathogen in the poultry industry, which can cause substantial economic losses. Recently, emerging evidence showed that miRNAs were involved in various viral and bacterial infections. To… read more here.

Keywords: gga mir; mir 181b; infection; chicken macrophages ... See more keywords
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A positive feedback loop between miR‐181b and STAT3 that affects Warburg effect in colon cancer via regulating PIAS3 expression

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Published in 2018 at "Journal of Cellular and Molecular Medicine"

DOI: 10.1111/jcmm.13786

Abstract: This study aimed to investigate the relationship between the expression of microRNA (miR)‐181b, protein inhibitor of activated STAT3 (PIAS3) and STAT3, and to examine the function of the miR‐181b/PIAS3/STAT3 axis on the Warburg effect and… read more here.

Keywords: effect; colon cancer; mir 181b; stat3 ... See more keywords
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Senomorphic properties of miR-181b in aged human aortic smooth muscle cells

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Published in 2023 at "Physiology"

DOI: 10.1152/physiol.2023.38.s1.5735166

Abstract: Introduction: Age associated large artery stiffness (LAS) is an independent predictor of adverse cardiovascular health outcomes in humans and has also been shown to be associated with the development of heart failure, kidney disease, and… read more here.

Keywords: cell; muscle cells; mir 181b; stiffness ... See more keywords
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Interaction of miR-181b and IFNA1 Polymorphisms on the Risk of Systemic Lupus Erythematosus

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Published in 2020 at "BioMed Research International"

DOI: 10.1155/2020/4757065

Abstract: Introduction A previous work has discovered that chromosome 1q32 locus linked to the risk of systemic lupus erythematosus (SLE) and miR-181b located on the susceptibility site with downregulation inversely correlating to its target molecular interferon… read more here.

Keywords: risk; ifna1; sle; risk systemic ... See more keywords
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Role of miR-181b/Notch1 Axis in circ_TNPO1 Promotion of Proliferation and Migration of Atherosclerotic Vascular Smooth Muscle Cells

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Published in 2022 at "Journal of Healthcare Engineering"

DOI: 10.1155/2022/4086935

Abstract: Background The role and expression level change in circ_TNPO1 (hsa_circ_0072951) in atherosclerosis (AS) and VSMC dysfunction remain unknown. In this study, we try to explore the effects of circ_TNPO1 on oxidized low-density lipoprotein (ox-LDL)-induced human… read more here.

Keywords: tnpo1; proliferation migration; mir 181b; circ tnpo1 ... See more keywords