miR‐182‐5p overexpression inhibits chondrogenesis by down‐regulating PTHLH
Sign Up to like & getrecommendations! Published in 2019 at "Cell Biology International"
DOI: 10.1002/cbin.11047
Abstract: Human bone marrow mesenchymal stem cells (hBM‐MSC) have the ability of differentiating into chondrocytes and osteoblasts. miR‐182‐5p promotes osteoclastogenesis and bone metastasis by up‐regulating the expression of parathyroid hormone‐like hormone (PTHLH). However, the function of… read more here.
Keywords: regulating pthlh; chondrogenesis; mir 182; 182 overexpression ... See more keywords
Up‐regulation of SNHG16 induced by CTCF accelerates cardiac hypertrophy by targeting miR‐182‐5p/IGF1 axis
Sign Up to like & getrecommendations! Published in 2020 at "Cell Biology International"
DOI: 10.1002/cbin.11333
Abstract: Long non‐coding RNA (lncRNA) SNHG16 has been reported to be significant regulators in multiple cancers. However, never has the relationship between it and cardiac hypertrophy been studied until now. In this study, angiotensin II (Ang… read more here.
Keywords: cardiac hypertrophy; mir 182; igf1; expression ... See more keywords
LncRNA CHRF aggravates myocardial ischemia/reperfusion injury by enhancing autophagy via modulation of the miR‐182‐5p/ATG7 pathway
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.22709
Abstract: Myocardial ischemia/reperfusion (I/R) injury is a very frequent cardiovascular disease and one of the leading causes of death. Abundant evidence has shown that long noncoding RNAs (lncRNAs) are crucial players in myocardial I/R injury. LncRNA… read more here.
Keywords: mir 182; chrf; myocardial injury; myocardial ischemia ... See more keywords
MiR‐182‐5p inhibited oxidative stress and apoptosis triggered by oxidized low‐density lipoprotein via targeting toll‐like receptor 4
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.26389
Abstract: MicroRNAs (miRNAs) exhibit various roles in multiple biological processes and abnormal expression of miR‐182‐5p has been involved in many diseases. However, the role miR‐182‐5p in Atherosclerosis (AS) remains poorly understood. In our current investigation, an… read more here.
Keywords: toll like; oxidized low; apoptosis; mir 182 ... See more keywords
Emodin inhibiting epithelial‐mesenchymal transition in pulmonary fibrosis through the c‐MYC/miR‐182‐5p/ZEB2 axis
Sign Up to like & getrecommendations! Published in 2022 at "Phytotherapy Research"
DOI: 10.1002/ptr.7680
Abstract: Emodin is a natural anthraquinone compound, which is the main component found in the traditional Chinese herb Polygonum cuspidatum. The anti‐fibrosis effects of Emodin have been reported. This study aimed to explore the specific mechanism… read more here.
Keywords: emt; myc mir; pulmonary fibrosis; fibrosis ... See more keywords
MiR-182 inhibits proliferation, migration, invasion and inflammation of endometrial stromal cells through deactivation of NF-κB signaling pathway in endometriosis
Sign Up to like & getrecommendations! Published in 2021 at "Molecular and Cellular Biochemistry"
DOI: 10.1007/s11010-020-03986-2
Abstract: Endometriosis affects about 10-15% women for reproductive age, but it is not currently curable and the underlying etiology for this disease is still not clear. In the present study, functions and mechanisms of miR-182 and… read more here.
Keywords: proliferation migration; endometriosis; mir 182; stromal cells ... See more keywords
LncRNA ADAMTS9-AS2 regulates ovarian cancer progression by targeting miR-182-5p/FOXF2 signaling pathway.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2018.09.179
Abstract: Increasing studies revealed that aberrant expression of long non-coding RNAs (lncRNAs) play critical roles in ovarian cancer (OC) progression. However, the roles and underlying mechanisms of ADAMTS9-AS2 in OC remain unclear. In the present study,… read more here.
Keywords: adamts9 as2; mir 182; ovarian cancer; cancer progression ... See more keywords
Circ_002664/miR-182-5p/Herpud1 pathway importantly contributes to OGD/R-induced neuronal cell apoptosis.
Sign Up to like & getrecommendations! Published in 2020 at "Molecular and cellular probes"
DOI: 10.1016/j.mcp.2020.101585
Abstract: OBJECTIVE Apoptosis is a prominent form of neuron death in cerebral ischemia-reperfusion-induced injury. Accompanied with the pathogenesis, Circ_002664 is upregulated. However, its role in the neuron apoptosis and the underlying mechanisms are unknown. METHODS In… read more here.
Keywords: 182 herpud1; apoptosis; mir 182; circ 002664 ... See more keywords
Ellagic acid protects rats from chronic renal failure via MiR-182/FOXO3a axis.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular immunology"
DOI: 10.1016/j.molimm.2021.08.007
Abstract: Studies showed that ellagic acid (EA) can significantly improve kidney function, but the renal-protective effects of EA and the potential mechanism require adequate elucidation. This study investigated the mechanisms of EA in chronic renal failure… read more here.
Keywords: renal failure; foxo3a; mir 182; chronic renal ... See more keywords
miR-182 prevented ototoxic deafness induced by co-administration of kanamycin and furosemide in rats
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DOI: 10.1016/j.neulet.2020.134861
Abstract: Ototoxic drugs may induce auditory sensory hair cell loss and permanent deafness; however, there is still no effective treatments or prevention strategies for this side effect. A recent study found that microRNA182 (miR-182) protected cochlear… read more here.
Keywords: hair; mir 182; administration kanamycin; kanamycin furosemide ... See more keywords
The miR‐182/SORT1 axis regulates vascular smooth muscle cell calcification in vitro and in vivo
Sign Up to like & getrecommendations! Published in 2018 at "Experimental Cell Research"
DOI: 10.1016/j.yexcr.2017.11.033
Abstract: &NA; Arterial calcification is a common feature of cardiovascular disease. Sortilin is involved in the development of atherosclerosis, but the specific mechanism is unclear. In this study, we established calcification models in vivo and in… read more here.
Keywords: sort1; mir 182; vascular smooth; calcification ... See more keywords