HDAC2‐mediated proliferation of trophoblast cells requires the miR‐183/FOXA1/IL‐8 signaling pathway
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30026
Abstract: Pre‐eclampsia (PE) is a major cause of maternal and perinatal death. Previous research has indicated the role of histone deacetylase 2 (HDAC2) in the pathogenesis of PE but the relevant molecular mechanisms are unknown. However,… read more here.
Keywords: proliferation migration; hdac2; mir 183; proliferation ... See more keywords
Overexpression of miR-183/-96/-182 triggers neuronal cell fate in Human Retinal Pigment Epithelial (hRPE) cells in culture.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2016.12.071
Abstract: miR-183 cluster, composed of miR-183/-96/-182 genes, is highly expressed in the adult retina, particularly in photoreceptors. It involves in development, maturation and normal function of neuroretina. Ectopic overexpression of miR-183/-96/-182 genes was performed to assess… read more here.
Keywords: mir 183; 183 182; hrpe cells; overexpression mir ... See more keywords
Phoenixin-14 regulates proliferation and apoptosis of vascular smooth muscle cells by modulation of KCNQ1OT1/miR-183-3p/CTNNB1 axis.
Sign Up to like & getrecommendations! Published in 2021 at "Environmental toxicology and pharmacology"
DOI: 10.1016/j.etap.2021.103655
Abstract: Phoenixin-14 was reported to be implicated in the process of blood glucose metabolism, reproduction, lipid deposition and cardioprotection. However, the role of phoenixin-14 has not been investigated in vascular smooth muscle cells (VSMCs). In this… read more here.
Keywords: mir 183; proliferation apoptosis; vascular smooth; phoenixin ... See more keywords
MiR-183 promotes preadipocyte differentiation by suppressing Smad4 in goats.
Sign Up to like & getrecommendations! Published in 2018 at "Gene"
DOI: 10.1016/j.gene.2018.05.022
Abstract: As a well-conserved microRNA, miR-183 is ubiquitously expressed in many tissues and cells including backfat and the 3T3-L1 adipocytes; however, the mechanisms regulating miR-183 in adipogenesis remain poorly understood. Here, we explored the expression pattern… read more here.
Keywords: 183 promotes; mir 183; preadipocyte differentiation; promotes preadipocyte ... See more keywords
Determination of the transcriptional level of long non-coding RNA NEAT-1, downstream target microRNAs, and genes targeted by microRNAs in diabetic neuropathy patients.
Sign Up to like & getrecommendations! Published in 2021 at "Immunology letters"
DOI: 10.1016/j.imlet.2021.01.007
Abstract: BACKGROUND Diabetic neuropathy (DN) is one of the microvascular complications of diabetes that leads to peripheral sensorimotor and autonomic nervous system damages. In this study, we first examined the expression of lncRNA NEAT-1 and its… read more here.
Keywords: neat downstream; mir 183; diabetic neuropathy; level ... See more keywords
miR-183 inhibits the viability, migration and invasion of epithelium on adenomyosis via targeting MMP-9.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of gynecology obstetrics and human reproduction"
DOI: 10.1016/j.jogoh.2022.102349
Abstract: BACKGROUND Adenomyosis refers to a pathological damage resulting from local and diffuse lesions in endometrium, caused by invasive endometrial gland and its mesenchyme. Our study aimed to reveal miR-183's role in the development of adenomyosis.… read more here.
Keywords: viability migration; mir 183; adenomyosis; migration invasion ... See more keywords
MicroRNA-183 exerts a protective role in lupus nephritis through blunting the activation of TGF-β/Smad/TLR3 pathway via reducing Tgfbr1.
Sign Up to like & getrecommendations! Published in 2020 at "Experimental cell research"
DOI: 10.1016/j.yexcr.2020.112138
Abstract: PURPOSE The role of microRNA (miR)-183 has been elucidated in systemic lupus erythematosus, while whether it is also engaged in the lupus nephritis (LN) development remains opaque. The intention of this study is to examine… read more here.
Keywords: tlr3 pathway; tgf smad; mir 183; expression ... See more keywords
miR-183-5p suppressed the invasion and migration of HTR-8/SVneo trophoblast cells partly via targeting MMP-9 in preeclampsia
Sign Up to like & getrecommendations! Published in 2020 at "Bioscience Reports"
DOI: 10.1042/bsr20192575
Abstract: Abstract Preeclampsia (PE), a common obstetrical disorder, is characterized by impaired migration and invasion abilities of trophoblastic cells. MicroRNA-183-5p (miR-183) was reported to regulate cell migration and invasion in various types of human cancers; however,… read more here.
Keywords: htr svneo; migration; invasion migration; mir 183 ... See more keywords
MicroRNA-183-5p contributes to malignant progression through targeting PDCD4 in human hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2020 at "Bioscience Reports"
DOI: 10.1042/bsr20201761
Abstract: Abstract Hepatocellular carcinoma (HCC) remains one of the most common malignant tumors worldwide. The present study aimed to investigate the biological role of microRNA-183-5p (miR-183-5p), a novel tumor-related microRNA (miRNA), in HCC and illuminate the… read more here.
Keywords: hepatocellular carcinoma; hcc; 183 knockdown; targeting pdcd4 ... See more keywords
Immune evasion by TGFβ-induced miR-183 repression of MICA/B expression in human lung tumor cells
Sign Up to like & getrecommendations! Published in 2019 at "Oncoimmunology"
DOI: 10.1080/2162402x.2018.1557372
Abstract: ABSTRACT Immune escape is a hallmark of cancer. In human lung cancer, we have identified a unique microRNA (miR)-based pathway employed by tumor cells to repress detection by immune cells via the NKG2D-MICA/B receptor-ligand system.… read more here.
Keywords: expression; human lung; mica; tumor cells ... See more keywords
LncRNA CRNDE acts as an oncogene in cervical cancer through sponging miR-183 to regulate CCNB1 expression.
Sign Up to like & getrecommendations! Published in 2019 at "Carcinogenesis"
DOI: 10.1093/carcin/bgz166
Abstract: Studies have identified a series of lncRNAs that contributed to various tumors, although the underlying mechanisms remain largely unclear. We proposed a ceRNA network and investigate relations among lncRNA/miRNA/mRNA in cervical cancer (CC). The genes… read more here.
Keywords: mir 183; crnde; cervical cancer; ccnb1 expression ... See more keywords