Circular RNA circRNA_15698 aggravates the extracellular matrix of diabetic nephropathy mesangial cells via miR‐185/TGF‐β1
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.26959
Abstract: Circular RNAs (circRNAs) are a novel type of noncoding RNAs that modulate the pathogenesis of multiple diseases. Nevertheless, the role of circRNAs in diabetic nephropathy (DN) pathogenesis is still ambiguous. In the current study, our… read more here.
Keywords: mesangial cells; circrna 15698; 185 tgf; mir 185 ... See more keywords
Long noncoding RNA NEAT1 promotes progression of glioma as a ceRNA by sponging miR‐185‐5p to stimulate DNMT1/mTOR signaling
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.29644
Abstract: Long noncoding RNA nuclear paraspeckle assembly transcript 1 (NEAT1) is regarded as an oncogene in multiple cancers. Previous studies have shown that NEAT1 is involved in the proliferation and tumorigenesis of glioma cells, while miR‐185‐5p… read more here.
Keywords: dnmt1 mtor; glioma; mir 185; mtor signaling ... See more keywords
Downregulation of miR-185 is a common pathogenic event in 22q11.2 deletion syndrome-related and idiopathic schizophrenia.
Sign Up to like & getrecommendations! Published in 2022 at "Metabolic brain disease"
DOI: 10.1007/s11011-022-00918-5
Abstract: Schizophrenia (SCZ) is known as a complicated mental disease with an unknown etiology. The microdeletion of 22q11.2 is the most potent genetic risk factor. Researchers are still trying to find which genes in the deletion… read more here.
Keywords: idiopathic scz; expression; hsa mir; deletion ... See more keywords
Long noncoding RNA LINC00958 promotes the oral squamous cell carcinoma by sponging miR-185-5p/YWHAZ.
Sign Up to like & getrecommendations! Published in 2019 at "Life sciences"
DOI: 10.1016/j.lfs.2019.116782
Abstract: AIM Increasing evidence has indicated the essential roles of long noncoding RNA (lncRNA) in the oral squamous cell carcinoma (OSCC). However, there are still numerous uncertain mechanisms for the pathophysiological process of OSCC. In this… read more here.
Keywords: long noncoding; mir 185; linc00958; 185 ywhaz ... See more keywords
Dysregulation of miR-185, miR-193a, and miR-450a in the skin are linked to the depressive phenotype
Sign Up to like & getrecommendations! Published in 2021 at "Progress in Neuro-Psychopharmacology and Biological Psychiatry"
DOI: 10.1016/j.pnpbp.2020.110052
Abstract: BACKGROUND Dysregulated micro-RNAs (miRNAs) in dermal fibroblasts of depressive subjects, indicate biomarker potential and can possibly aid clinical diagnostics. To overcome methodological challenges related to human experiments and fibroblast cultures, we here validate 38 miRNAs… read more here.
Keywords: mir 450a; mir 185; mir; dysregulation ... See more keywords
Extracellular vesicle-cargo miR-185-5p reflects type II alveolar cell death after oxidative stress
Sign Up to like & getrecommendations! Published in 2020 at "Cell Death Discovery"
DOI: 10.1038/s41420-020-00317-8
Abstract: Acute respiratory distress syndrome (ARDS) is a devastating syndrome responsible for significant morbidity and mortality. Diffuse alveolar epithelial cell death, including but not limited to apoptosis and necroptosis, is one of the hallmarks of ARDS.… read more here.
Keywords: extracellular vesicle; cell death; cargo mir; mir 185 ... See more keywords
Huayu Tongmai Granules protects against vascular endothelial dysfunction via up-regulating miR-185 and down-regulating RAGE
Sign Up to like & getrecommendations! Published in 2018 at "Bioscience Reports"
DOI: 10.1042/bsr20180674
Abstract: Objective: Receptor of advanced glycation end products (RAGE) is a membrane protein that contributes to the initiation and progression of diabetic vascular complications, which is reported as a target of miR-185. Huayu Tongmai Granules is… read more here.
Keywords: tongmai granules; rage; huayu tongmai; mir 185 ... See more keywords
Highly-expressed lncRNA FOXD2-AS1 in adipose mesenchymal stem cell derived exosomes affects HaCaT cells via regulating miR-185-5p/ROCK2 axis
Sign Up to like & getrecommendations! Published in 2023 at "Adipocyte"
DOI: 10.1080/21623945.2023.2173513
Abstract: ABSTRACT The healing of skin wounds is a highly coordinated multi-step process that occurs after trauma including surgical incisions, thermal burns, and chronic ulcers. In this study, the authors investigated lncRNA FOXD2-AS1 function in adipose… read more here.
Keywords: lncrna foxd2; mir 185; cell; foxd2 as1 ... See more keywords
miR-185/P2Y6 Axis Inhibits Angiotensin II-Induced Human Aortic Vascular Smooth Muscle Cell Proliferation.
Sign Up to like & getrecommendations! Published in 2017 at "DNA and Cell Biology"
DOI: 10.1089/dna.2016.3605
Abstract: The abnormal proliferation and apoptosis of human aortic vascular smooth muscle cells (HAVSMCs) play an important role in the pathogenesis of hypertension. Recent study revealed that angiotensin II (Ang II) could elicit HAVSMC dysfunction, to… read more here.
Keywords: mir 185; aortic vascular; vascular smooth; proliferation ... See more keywords
Circ_0005615 contributes to the progression and Bortezomib resistance of multiple myeloma by sponging miR-185-5p and upregulating IRF4
Sign Up to like & getrecommendations! Published in 2022 at "Anti-Cancer Drugs"
DOI: 10.1097/cad.0000000000001378
Abstract: Circular RNAs (circRNAs) have been shown to play critical regulatory roles in multiple myeloma progression. Here, we aimed to explore the biologic role of circ_0005615 in multiple myeloma progression and its associated mechanism. Cell counting… read more here.
Keywords: mir 185; multiple myeloma; bortezomib resistance; circ 0005615 ... See more keywords
MZB1 targeted by miR-185-5p inhibits the migration of human periodontal ligament cells through NF-κB signaling and promotes alveolar bone loss.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of periodontal research"
DOI: 10.1111/jre.13014
Abstract: OBJECTIVE To explore the role of Marginal Zone B and B-1 Cell-Specific Protein (MZB1), a novel molecule associated with periodontitis, in migration of human periodontal ligament cells (hPDLCs) and alveolar bone orchestration. BACKGROUND MZB1 is… read more here.
Keywords: alveolar bone; mzb1; loss; migration ... See more keywords