Articles with "mir 185" as a keyword



Circular RNA circRNA_15698 aggravates the extracellular matrix of diabetic nephropathy mesangial cells via miR‐185/TGF‐β1

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Published in 2019 at "Journal of Cellular Physiology"

DOI: 10.1002/jcp.26959

Abstract: Circular RNAs (circRNAs) are a novel type of noncoding RNAs that modulate the pathogenesis of multiple diseases. Nevertheless, the role of circRNAs in diabetic nephropathy (DN) pathogenesis is still ambiguous. In the current study, our… read more here.

Keywords: mesangial cells; circrna 15698; 185 tgf; mir 185 ... See more keywords

Long noncoding RNA NEAT1 promotes progression of glioma as a ceRNA by sponging miR‐185‐5p to stimulate DNMT1/mTOR signaling

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Published in 2020 at "Journal of Cellular Physiology"

DOI: 10.1002/jcp.29644

Abstract: Long noncoding RNA nuclear paraspeckle assembly transcript 1 (NEAT1) is regarded as an oncogene in multiple cancers. Previous studies have shown that NEAT1 is involved in the proliferation and tumorigenesis of glioma cells, while miR‐185‐5p… read more here.

Keywords: dnmt1 mtor; glioma; mir 185; mtor signaling ... See more keywords

Downregulation of miR-185 is a common pathogenic event in 22q11.2 deletion syndrome-related and idiopathic schizophrenia.

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Published in 2022 at "Metabolic brain disease"

DOI: 10.1007/s11011-022-00918-5

Abstract: Schizophrenia (SCZ) is known as a complicated mental disease with an unknown etiology. The microdeletion of 22q11.2 is the most potent genetic risk factor. Researchers are still trying to find which genes in the deletion… read more here.

Keywords: idiopathic scz; expression; hsa mir; deletion ... See more keywords

Long noncoding RNA LINC00958 promotes the oral squamous cell carcinoma by sponging miR-185-5p/YWHAZ.

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Published in 2019 at "Life sciences"

DOI: 10.1016/j.lfs.2019.116782

Abstract: AIM Increasing evidence has indicated the essential roles of long noncoding RNA (lncRNA) in the oral squamous cell carcinoma (OSCC). However, there are still numerous uncertain mechanisms for the pathophysiological process of OSCC. In this… read more here.

Keywords: long noncoding; mir 185; linc00958; 185 ywhaz ... See more keywords
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Dysregulation of miR-185, miR-193a, and miR-450a in the skin are linked to the depressive phenotype

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Published in 2021 at "Progress in Neuro-Psychopharmacology and Biological Psychiatry"

DOI: 10.1016/j.pnpbp.2020.110052

Abstract: BACKGROUND Dysregulated micro-RNAs (miRNAs) in dermal fibroblasts of depressive subjects, indicate biomarker potential and can possibly aid clinical diagnostics. To overcome methodological challenges related to human experiments and fibroblast cultures, we here validate 38 miRNAs… read more here.

Keywords: mir 450a; mir 185; mir; dysregulation ... See more keywords
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Extracellular vesicle-cargo miR-185-5p reflects type II alveolar cell death after oxidative stress

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Published in 2020 at "Cell Death Discovery"

DOI: 10.1038/s41420-020-00317-8

Abstract: Acute respiratory distress syndrome (ARDS) is a devastating syndrome responsible for significant morbidity and mortality. Diffuse alveolar epithelial cell death, including but not limited to apoptosis and necroptosis, is one of the hallmarks of ARDS.… read more here.

Keywords: extracellular vesicle; cell death; cargo mir; mir 185 ... See more keywords

Huayu Tongmai Granules protects against vascular endothelial dysfunction via up-regulating miR-185 and down-regulating RAGE

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Published in 2018 at "Bioscience Reports"

DOI: 10.1042/bsr20180674

Abstract: Objective: Receptor of advanced glycation end products (RAGE) is a membrane protein that contributes to the initiation and progression of diabetic vascular complications, which is reported as a target of miR-185. Huayu Tongmai Granules is… read more here.

Keywords: tongmai granules; rage; huayu tongmai; mir 185 ... See more keywords

MiR-185-5p is Involved in Regulating the Abnormal Proliferation of Retinal Microvascular Endothelial Cells via Targeting CXCR4

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Published in 2024 at "Current Eye Research"

DOI: 10.1080/02713683.2024.2430224

Abstract: Abstract Purpose This study aimed to explore the expression profile of miR-185-5p in proliferative DR (PDR), and further evaluate its diagnostic value and possible mechanism of miR-185-5p in PDR. Methods The level of miR-185-5p was… read more here.

Keywords: involved regulating; mir 185; proliferation; endothelial cells ... See more keywords

Highly-expressed lncRNA FOXD2-AS1 in adipose mesenchymal stem cell derived exosomes affects HaCaT cells via regulating miR-185-5p/ROCK2 axis

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Published in 2023 at "Adipocyte"

DOI: 10.1080/21623945.2023.2173513

Abstract: ABSTRACT The healing of skin wounds is a highly coordinated multi-step process that occurs after trauma including surgical incisions, thermal burns, and chronic ulcers. In this study, the authors investigated lncRNA FOXD2-AS1 function in adipose… read more here.

Keywords: lncrna foxd2; mir 185; cell; foxd2 as1 ... See more keywords

miR-185/P2Y6 Axis Inhibits Angiotensin II-Induced Human Aortic Vascular Smooth Muscle Cell Proliferation.

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Published in 2017 at "DNA and Cell Biology"

DOI: 10.1089/dna.2016.3605

Abstract: The abnormal proliferation and apoptosis of human aortic vascular smooth muscle cells (HAVSMCs) play an important role in the pathogenesis of hypertension. Recent study revealed that angiotensin II (Ang II) could elicit HAVSMC dysfunction, to… read more here.

Keywords: mir 185; aortic vascular; vascular smooth; proliferation ... See more keywords

Circ_0005615 contributes to the progression and Bortezomib resistance of multiple myeloma by sponging miR-185-5p and upregulating IRF4

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Published in 2022 at "Anti-Cancer Drugs"

DOI: 10.1097/cad.0000000000001378

Abstract: Circular RNAs (circRNAs) have been shown to play critical regulatory roles in multiple myeloma progression. Here, we aimed to explore the biologic role of circ_0005615 in multiple myeloma progression and its associated mechanism. Cell counting… read more here.

Keywords: mir 185; multiple myeloma; bortezomib resistance; circ 0005615 ... See more keywords