lncRNA PVT1 aggravates doxorubicin-induced cardiomyocyte apoptosis by targeting the miR-187-3p/AGO1 axis.
Sign Up to like & getrecommendations! Published in 2019 at "Molecular and cellular probes"
DOI: 10.1016/j.mcp.2019.101490
Abstract: OBJECTIVES To investigate the effect of long non-coding (lnc) RNA PVT1 on apoptosis induced by doxorubicin-induced cardiotoxicity. METHODS We analyzed the expression levels of lncRNA PVT1, miR-187-3p, using reverse transcription real-time quantitative PCR (RT-qPCR) in… read more here.
Keywords: mir 187; lncrna pvt1; doxorubicin induced; apoptosis ... See more keywords
LncRNA-PVT1 inhibition protects neuron injury during cerebral ischemia injury through targeting the miRNA-187-3p-MyD88 signaling pathway.
Sign Up to like & getrecommendations! Published in 2022 at "Current molecular medicine"
DOI: 10.2174/1566524022666220621124207
Abstract: BACKGROUND Cerebral ischemia/reperfusion (I/R) injury which leads to neurons damage, is one of the major causes for morbidity. Currently, the underlying mechanisms remain largely elusive. METHODS This study aimed to investigate the role of long… read more here.
Keywords: myd88; cerebral ischemia; neuron injury; injury ... See more keywords
MiR-187 influences cisplatin-resistance of gastric cancer cells through regulating the TGF-β/Smad signaling pathway.
Sign Up to like & getrecommendations! Published in 2019 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_201911_19556
Abstract: OBJECTIVE To explore the effect of micro-ribonucleic acid (miR)-187 on cisplatin (DDP) resistance of gastric cancer cells by regulating the transforming growth factor-β (TGF-β)/Smad signaling pathway. MATERIALS AND METHODS DDP-sensitivities in GES-1, SGC7901, and SGC7901/DDP… read more here.
Keywords: mir 187; gastric cancer; group; 187 inhibitor ... See more keywords
Taxol‑resistant breast cancer cell‑derived exosome‑delivered miR‑187‑5p regulates the growth of breast cancer cells via ABCD2 and Wnt/β‑catenin signaling
Sign Up to like & getrecommendations! Published in 2023 at "Oncology Letters"
DOI: 10.3892/ol.2023.13705
Abstract: Acquired resistance to Taxol (TAX) contributes to clinical treatment failure and significantly reduces the survival rate of patients. The present study aimed to explore the effects of exosomal microRNA (miR)-187-5p on TAX resistance in breast… read more here.
Keywords: breast cancer; mir 187; cell; tax ... See more keywords