Long non-coding RNA CASC2 protect ROS-induced Oxidative stress in myocardial infarction by miR-18a/SIRT2.
Sign Up to like & getrecommendations! Published in 2021 at "Biotechnology and applied biochemistry"
DOI: 10.1002/bab.2252
Abstract: BACKGROUND We aimed to investigate the function and its possible mechanisms of long non-coding RNA (lncRNA) in acute myocardial infarction (AMI) model. METHODS Patients with AMI and normal volunteers were collected from our hospital. Sprague… read more here.
Keywords: induced oxidative; mir 18a; casc2; ros induced ... See more keywords
The MicroRNA, miR‐18a, Regulates NeuroD and Photoreceptor Differentiation in the Retina of Zebrafish
Sign Up to like & getrecommendations! Published in 2019 at "Developmental Neurobiology"
DOI: 10.1002/dneu.22666
Abstract: During embryonic retinal development, six types of retinal neurons are generated from multipotent progenitors in a strict spatiotemporal pattern. This pattern requires cell cycle exit (i.e. neurogenesis) and differentiation to be precisely regulated in a… read more here.
Keywords: photoreceptor differentiation; 18a regulates; photoreceptor; regulates neurod ... See more keywords
Long noncoding RNA WDFY3‐AS2 suppresses tumor progression by acting as a competing endogenous RNA of microRNA‐18a in ovarian cancer
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.29028
Abstract: Ovarian cancer (OC) is a fatal cancer in women, mainly due to its aggressive nature and poor survival rate. The lncRNA‐miRNA‐mRNA (long noncoding RNA‐microRNA‐messenger RNA) interaction is promising biomarkers for the improving prognosis of OC.… read more here.
Keywords: mir 18a; wdfy3 as2; ovarian cancer;
Disruption of miR-18a Alters Proliferation, Photoreceptor Replacement Kinetics, Inflammatory Signaling, and Microglia/Macrophage Numbers During Retinal Regeneration in Zebrafish.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular neurobiology"
DOI: 10.1007/s12035-022-02783-w
Abstract: In mammals, photoreceptor loss causes permanent blindness, but in zebrafish (Danio rerio), photoreceptor loss reprograms Müller glia to function as stem cells, producing progenitors that regenerate photoreceptors. MicroRNAs (miRNAs) regulate CNS neurogenesis, but the roles… read more here.
Keywords: photoreceptor regeneration; mir 18a; mir 18ami5012; photoreceptor ... See more keywords
Long non-coding RNA CASC2 targeting miR-18a suppresses glioblastoma cell growth, metastasis and EMT in vitro and in vivo
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Biosciences"
DOI: 10.1007/s12038-020-00077-8
Abstract: Long non-coding RNAs (lncRNAs) cancer susceptibility candidate 2 (CASC2) has been characterized as a tumor suppressor in glioma. Although CASC2 may predict the prognosis of glioma patients, the role and mechanism of CASC2 in human… read more here.
Keywords: cell growth; mir 18a; casc2; metastasis ... See more keywords
Long non-coding RNA UCA1 desensitizes breast cancer cells to trastuzumab by impeding miR-18a repression of Yes-associated protein 1.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.02.006
Abstract: Breast cancer resistance to the monoclonal erbB2/HER2 antibody trastuzumab (or herceptin) has become a significant obstacle in clinical targeted therapy of HER2-positive breast cancer. Previous research demonstrated that such drug resistance may be related to… read more here.
Keywords: cancer; mir 18a; cancer cells; breast cancer ... See more keywords
Long non-coding RNA cancer susceptibility candidate 2 regulates the function of human fibroblast-like synoviocytes via the microRNA-18a-5p/B-cell translocation gene 3 signaling axis in rheumatoid arthritis
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2021.2022075
Abstract: ABSTRACT Rheumatoid arthritis (RA) is a perennial inflammatory condition. Preliminary research indicated that long non-coding (lnc)RNA cancer susceptibility candidate 2 (CASC2) was downregulated in the serum of RA patients. Our study was designed to reveal… read more here.
Keywords: mir 18a; non coding; casc2; rheumatoid arthritis ... See more keywords
Expression of miR‐18a and miR‐34c in circulating monocytes associated with vulnerability to type 2 diabetes mellitus and insulin resistance
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.13240
Abstract: Chronic stress may facilitate the development of metabolic disorders including insulin resistance (IR) and type 2 diabetes mellitus (T2DM). MiR‐18a and miR‐34c modulate central cell responsiveness to stress by targeting glucocorticoid receptor (GR) and corticotropin‐releasing… read more here.
Keywords: 18a mir; expression; mir 18a; insulin resistance ... See more keywords
miR-18a-5p Facilitates Malignant Progression of Head and Neck Squamous Cell Carcinoma Cells via Modulating SORBS2
Sign Up to like & getrecommendations! Published in 2021 at "Computational and Mathematical Methods in Medicine"
DOI: 10.1155/2021/5953881
Abstract: This study attempted to investigate possible molecular mechanism and role of miR-18a-5p in head and neck squamous cell carcinoma (HNSCC). Differential miRNAs and their possible targets were analyzed through TCGA database. By conducting qRT-PCR, miR-18a-5p… read more here.
Keywords: neck squamous; cell carcinoma; squamous cell; mir 18a ... See more keywords
Detection of exosomal miR-18a and miR-222 levels in Egyptian patients with hepatic cirrhosis and hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Immunopathology and Pharmacology"
DOI: 10.1177/03946320221097832
Abstract: Background Hepatocellular carcinoma (HCC) is known to be the second leading cause of cancer-related mortality worldwide. For improving the prognosis as well as reducing the rate of mortality, early diagnosis of HCC is a must.… read more here.
Keywords: mir 18a; liver cirrhosis; 18a mir; cirrhosis ... See more keywords
MiR-18a regulates myoblasts proliferation by targeting Fgf1
Sign Up to like & getrecommendations! Published in 2018 at "PLoS ONE"
DOI: 10.1371/journal.pone.0201551
Abstract: MiRNAs play an important role in cell proliferation, apoptosis, and differentiation. MiR-18a is increasingly being recognized as a regulator of cancer pathogenesis. Here, we discovered that miR-18a participates in myoblasts proliferation. Expression of miR-18a was… read more here.
Keywords: myoblasts proliferation; 18a regulates; fgf1; mir 18a ... See more keywords