miR‐192‐5p mediates hypoxia/reoxygenation‐induced apoptosis in H9c2 cardiomyocytes via targeting of FABP3
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.21873
Abstract: Myocardial ischemia/reperfusion (I/R) injury is a leading cause of morbidity and mortality. In this study, we investigated the role of miR‐192‐5p in hypoxia/reoxygenation (H/R)‐induced cardiomyocyte apoptosis. H9c2 cardiomyocytes were subjected to H/R and tested for… read more here.
Keywords: mir 192; apoptosis h9c2; hypoxia reoxygenation; apoptosis ... See more keywords
Small extracellular vesicles containing miR-192/215 mediate hypoxia-induced cancer-associated fibroblast development in head and neck squamous cell carcinoma.
Sign Up to like & getrecommendations! Published in 2021 at "Cancer letters"
DOI: 10.1016/j.canlet.2021.01.006
Abstract: The mechanisms underlying the hypoxic cancer cell-mediated differentiation of cancer-associated fibroblasts (CAFs) have not been elucidated yet. The present study showed that the hypoxic head and neck squamous cell carcinoma (HNSCC) cells promoted CAF-like differentiation… read more here.
Keywords: 192 215; mir 192; cancer; cancer associated ... See more keywords
Dysregulation of miR-192-5p in acute pancreatitis patients with nonalcoholic fatty liver and its functional role in acute pancreatitis progression
Sign Up to like & getrecommendations! Published in 2020 at "Bioscience Reports"
DOI: 10.1042/bsr20194345
Abstract: Abstract Background: Nonalcoholic fatty liver disease (NAFLD) is a frequent metabolic disease and has been demonstrated to contribute to the severity of acute pancreatitis (AP). The present study aimed to investigate the aberrant expression of… read more here.
Keywords: acute pancreatitis; mir 192; fatty liver; cell ... See more keywords
MiR-192 attenuates high glucose-induced pyroptosis in retinal pigment epithelial cells via inflammasome modulation.
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2022.2044734
Abstract: Diabetic retinopathy is one of the most characteristic complications of diabetes mellitus, and pyroptosis plays acrucial role in the onset and development of diabetic retinopathy. Although microRNA-192 (miR-192) has been demonstrated to be involved in… read more here.
Keywords: mir 192; cell pyroptosis; pyroptosis retinal; pyroptosis ... See more keywords
Knockdown of deleterious miRNA in progenitor cell–derived small extracellular vesicles enhances tissue repair in myocardial infarction
Sign Up to like & getrecommendations! Published in 2023 at "Science Advances"
DOI: 10.1126/sciadv.abo4616
Abstract: Small extracellular vesicles (sEVs) play a critical role in cardiac cell therapy by delivering molecular cargo and mediating cellular signaling. Among sEV cargo molecule types, microRNA (miRNA) is particularly potent and highly heterogeneous. However, not… read more here.
Keywords: cell; extracellular vesicles; myocardial infarction; mir 192 ... See more keywords
Circ_0000189 Promotes the Malignancy of Glioma Cells via Regulating miR-192-5p-ZEB2 Axis
Sign Up to like & getrecommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2022/2521951
Abstract: Background Some recent studies have reported the role of circular RNAs (circRNAs) in modulating the tumorigenesis of human malignancies. Nevertheless, the expression characteristics, biological functions, and regulatory mechanism of circ_0000189 in glioma are unclear. Methods… read more here.
Keywords: zeb2; glioma cells; circ 0000189; mir 192 ... See more keywords
Exosome-Encapsulated miR-31, miR-192, and miR-375 Serve as Clinical Biomarkers of Gastric Cancer
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Oncology"
DOI: 10.1155/2023/7335456
Abstract: In recent years, microRNAs (miRNAs) derived from exosomes have been attracting attention as novel clinical biomarkers in a variety of cancers. In this study, plasma samples from 60 gastric cancer (GC) patients and 63 healthy… read more here.
Keywords: clinical biomarkers; mir 375; 192 mir; mir 192 ... See more keywords
Abstract 3834: Histone methyltransferase SET8 is regulated by miR-192/-215 and induces oncogene-induced senescence via p53-dependent DNA damage in human gastric carcinoma cells
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Research"
DOI: 10.1158/1538-7445.am2020-3834
Abstract: Proceedings: AACR Annual Meeting 2020; April 27-28, 2020 and June 22-24, 2020; Philadelphia, PA Purpose: This aim of study was to investigate the clinicopathologic significance and potential role of histone methyltransferase SET8 in the progression… read more here.
Keywords: 192 215; histone methyltransferase; senescence; mir 192 ... See more keywords
LncRNA KCNQ1OT1 attenuates sepsis-induced myocardial injury via regulating miR-192-5p/XIAP axis
Sign Up to like & getrecommendations! Published in 2020 at "Experimental Biology and Medicine"
DOI: 10.1177/1535370220908041
Abstract: Myocardial dysfunction is a prime cause of death in sepsis. This study is to delve into the function of lncRNA KCNQ1OT1 in myocardial injury induced by sepsis. Sepsis-induced myocardial injury model in rat was initiated… read more here.
Keywords: sepsis; myocardial injury; kcnq1ot1; mir 192 ... See more keywords
Circulating liver-specific microRNAs in cynomolgus monkeys
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Toxicologic Pathology"
DOI: 10.1293/tox.2017-0036
Abstract: Circulating microRNAs (miRNAs) can potentially be used as sensitive and specific biomarkers for tissue injury. However, the usefulness of circulating miRNAs as safety biomarkers in nonclinical toxicological studies using nonhuman primates is debatable owing to… read more here.
Keywords: liver specific; cynomolgus monkeys; liver; mir 122 ... See more keywords
Down-regulation of miR-192 protects against rat ischemia-reperfusion injury after myocardial infarction.
Sign Up to like & getrecommendations! Published in 2020 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_202011_23749
Abstract: Since this article has been suspected of research misconduct and the corresponding authors did not respond to our request to prove originality of data and figures, "Down-regulation of miR-192 protects against rat ischemia-reperfusion injury after… read more here.
Keywords: mir 192; ischemia reperfusion; 192 protects; rat ischemia ... See more keywords