The clinical value of miR‐193a‐3p in non‐small cell lung cancer and its potential molecular mechanism explored in silico using RNA‐sequencing and microarray data
Sign Up to like & getrecommendations! Published in 2018 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.12354
Abstract: miR‐193a‐3p is a tumor‐related miRNA playing an essential role in tumorigenesis and progression of non‐small cell lung cancer (NSCLC). The objective of the present study was to investigate the relationship between miR‐193a‐3p expression and clinical… read more here.
Keywords: value; cell lung; mir 193a; non small ... See more keywords
LINC01224 accelerates malignant transformation via MiR‐193a‐5p/CDK8 axis in gastric cancer
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DOI: 10.1002/cam4.3726
Abstract: Gastric cancer (GC) is a malignant tumor with a significantly high mortality rate, yet, its pathogenesis is not fully understood. Bioinformatics predicted that LINC01224 is highly expressed in stomach adenocarcinoma (STAD), and showed that LINC01224… read more here.
Keywords: 193a cdk8; gastric cancer; cdk8 axis; mir 193a ... See more keywords
NEAT1/miR‐193a‐3p/SOX5 axis regulates cartilage matrix degradation in human osteoarthritis
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DOI: 10.1002/cbin.11291
Abstract: Long non‐coding RNAs (lncRNAs) were reported to be involved in the progression of osteoarthritis (OA). The aim of this work was to explore the functional role of lncRNA nuclear‐enriched abundant transcript 1 (NEAT1) in OA.… read more here.
Keywords: sox5 axis; neat1 mir; 193a sox5; sox5 ... See more keywords
The LncRNA H19/miR‐193a‐3p axis modifies the radio‐resistance and chemotherapeutic tolerance of hepatocellular carcinoma cells by targeting PSEN1
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DOI: 10.1002/jcb.26883
Abstract: This study was designated to verify if the lncRNA H19/miR‐193a‐3p axis would play a regulatory role in the radio‐/chemo‐resistances of HCC cells through targeting PSEN1. Within the study, five human HCC cell lines were prepared,… read more here.
Keywords: psen1; lncrna h19; mir 193a; h19 mir ... See more keywords
MiR‐193a‐3p and miR‐224 mediate renal cell carcinoma progression by targeting alpha‐2,3‐sialyltransferase IV and the phosphatidylinositol 3 kinase/Akt pathway
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DOI: 10.1002/mc.22826
Abstract: Tumor metastasis is a major cause of cancer‐related death in renal cell carcinoma (RCC). MicroRNAs (miRNAs) have been widely known to modulate proliferation invasion, metastasis, and apoptosis of cancer cells. In this study, we aimed… read more here.
Keywords: 193a mir; mir 224; mir; rcc ... See more keywords
Circular RNA ACACA negatively regulated p53‐modulated mevalonate pathway to promote colorectal tumorigenesis via regulating miR‐193a/b‐3p/HDAC3 axis
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DOI: 10.1002/mc.23522
Abstract: This study aimed to explore the biological functions and underlying mechanism of circRNA acetyl‐CoA carboxylase alpha (circACACA) in colorectal cancer (CRC). The RNA and protein levels were detected by qRT‐PCR and western blot assays. The… read more here.
Keywords: pathway; circacaca; crc; p53 ... See more keywords
Magnesium isoglycyrrhizinate ameliorates fructose-induced podocyte apoptosis through downregulation of miR-193a to increase WT1.
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DOI: 10.1016/j.bcp.2019.05.016
Abstract: High fructose intake is a risk of glomerular podocyte dysfunction. Podocyte apoptosis has emerged as a major cause of podocyte loss, exacerbating proteinuria. Magnesium isoglycyrrhizinate (MgIG) is usually used as a hepatoprotective agent in clinic.… read more here.
Keywords: podocyte apoptosis; fructose induced; mir 193a; wt1 ... See more keywords
LncRNA KCNQ1OT1 contributes to the progression and chemoresistance in acute myeloid leukemia by modulating Tspan3 through suppressing miR-193a-3p.
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DOI: 10.1016/j.lfs.2019.117161
Abstract: AIMS Acute myeloid leukemia (AML) is an aggressive cancer that invariably produces drug resistance after treatment. The aim is to explore the role of lncRNA potassium voltage-gated channel subfamily Q member 1 overlapping transcript 1… read more here.
Keywords: progression chemoresistance; adr; mir 193a; kcnq1ot1 ... See more keywords
Dysregulation of miR-185, miR-193a, and miR-450a in the skin are linked to the depressive phenotype
Sign Up to like & getrecommendations! Published in 2021 at "Progress in Neuro-Psychopharmacology and Biological Psychiatry"
DOI: 10.1016/j.pnpbp.2020.110052
Abstract: BACKGROUND Dysregulated micro-RNAs (miRNAs) in dermal fibroblasts of depressive subjects, indicate biomarker potential and can possibly aid clinical diagnostics. To overcome methodological challenges related to human experiments and fibroblast cultures, we here validate 38 miRNAs… read more here.
Keywords: mir 450a; mir 185; mir; dysregulation ... See more keywords
Extracellular vesicles carrying miR-193a derived from mesenchymal stem cells impede cell proliferation, migration and invasion of colon cancer by downregulating FAK.
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DOI: 10.1016/j.yexcr.2020.112144
Abstract: MicroRNA (miR) deregulation is frequently seen in colon cancer. In this study, we sought to investigate biological effects of miR-193a on colon cancer and its underlying mechanism. Microarray analysis was conducted to obtain the differentially… read more here.
Keywords: proliferation migration; colon; mir 193a; colon cancer ... See more keywords
MVP-mediated exosomal sorting of miR-193a promotes colon cancer progression
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DOI: 10.1038/ncomms14448
Abstract: Exosomes are emerging mediators of intercellular communication; whether the release of exosomes has an effect on the exosome donor cells in addition to the recipient cells has not been investigated to any extent. Here, we… read more here.
Keywords: colon; mir 193a; colon cancer; progression ... See more keywords