MicroRNA‐194 overexpression protects against hypoxia/reperfusion‐induced HK‐2 cell injury through direct targeting Rheb
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.28114
Abstract: Renal ischemia‐reperfusion injury, a major cause of renal failure, always leads to acute kidney injury and kidney fibrosis. MicroRNAs (miRs) have been reported to be associated with renal ischemia‐reperfusion injury. miR‐194 was downregulated following renal… read more here.
Keywords: renal ischemia; ischemia reperfusion; reperfusion injury; injury ... See more keywords
miR‐194 relieve neuropathic pain and prevent neuroinflammation via targeting FOXA1
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.29598
Abstract: The emerging role of microRNAs (miRNAs) have been deeply explored in multiple diseases including neuropathic pain. miR‐194 was widely reported to be a tumor suppressor and was related to the inflammatory response. The critical role… read more here.
Keywords: 194 neuropathic; neuroinflammation; neuropathic pain; via targeting ... See more keywords
LncRNA MALAT1 modified progression of clear cell kidney carcinoma (KIRC) by regulation of miR‐194‐5p/ACVR2B signaling
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.22926
Abstract: This investigation was purposed to extrapolate whether and how lncRNA MALAT1, miR‐194‐5p, and ACVR2B altered development of clear cell kidney carcinoma (KIRC). We totally gathered 318 pairs of KIRC tissues and adjacent normal tissues, and… read more here.
Keywords: malat1 mir; malat1; acvr2b; kirc ... See more keywords
MicroRNA-194 inhibits PRC1 activation of the Wnt/β-catenin signaling pathway to prevent tumorigenesis by elevating self-renewal of non-side population cells and side population cells in esophageal cancer stem cells.
Sign Up to like & getrecommendations! Published in 2021 at "Cell and tissue research"
DOI: 10.1007/s00441-021-03412-z
Abstract: Esophageal cancer (EC) is a leading cause of cancer-related deaths worldwide. Recent studies highlight roles for microRNAs (miRNAs) in EC. Microarray analysis identified miR-194 as downregulated in EC. However, little is known about the role… read more here.
Keywords: side population; catenin signaling; signaling pathway; stem cells ... See more keywords
Downregulation of serum miR-194 predicts poor prognosis in osteosarcoma patients.
Sign Up to like & getrecommendations! Published in 2020 at "Annals of diagnostic pathology"
DOI: 10.1016/j.anndiagpath.2020.151488
Abstract: BACKGROUND Circulating microRNAs (miRNAs) have promising potential as diagnostic and prognostic biomarkers for osteosarcoma. This study aimed to explore the expression pattern of serum miR-194 and its potential clinical value in patients with osteosarcoma. METHODS… read more here.
Keywords: osteosarcoma patients; prognosis osteosarcoma; serum mir; mir 194 ... See more keywords
MicroNAR-194-5p hinders the activation of NLRP3 inflammasomes and alleviates neuroinflammation during intracerebral hemorrhage by blocking the interaction between TRAF6 and NLRP3
Sign Up to like & getrecommendations! Published in 2021 at "Brain Research"
DOI: 10.1016/j.brainres.2020.147228
Abstract: The possible role of miR-194-5p in brain and neurodegenerative diseases has been reported, but its role in intracerebral hemorrhage (ICH) has not been studied. This study estimated the mechanism of miR-194-5p in ICH. ICH rat… read more here.
Keywords: traf6 nlrp3; traf6; nlrp3 inflammasomes; activation nlrp3 ... See more keywords
miR-194-5p down-regulates tumor cell PD-L1 expression and promotes anti-tumor immunity in pancreatic cancer.
Sign Up to like & getrecommendations! Published in 2021 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2021.107822
Abstract: Pancreatic cancer is a highly malignant cancer of the digestive tract. Studies have shown that in some types of cancer, a high level of microRNA-194-5p (miR-194-5p) is beneficial for controlling tumor progression, while in other… read more here.
Keywords: pancreatic cancer; anti tumor; expression; cancer ... See more keywords
MicroRNA-194 acts as a suppressor during abdominal aortic aneurysm via inhibition of KDM3A-mediated BNIP3.
Sign Up to like & getrecommendations! Published in 2021 at "Life sciences"
DOI: 10.1016/j.lfs.2021.119309
Abstract: AIMS Abdominal aortic aneurysm (AAA) is a serious disorder with a high disability rates and mortality rates. Accumulating evidence has identified the vital functions of microRNAs (miRNAs) in the treatment of AAA. Hence, this study… read more here.
Keywords: aortic aneurysm; kdm3a; expression; kdm3a mediated ... See more keywords
miR-194-Loaded Gelatin Nanospheres Target MEF2C to Suppress Muscle Atrophy in a Mechanical Unloading Model.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.1c00121
Abstract: Muscle atrophy usually occurs under mechanical unloading, which increases the risk of injury to reduce the functionality of the moving system, while there is still no effective therapy until now. It was found that miR-194… read more here.
Keywords: mir 194; 194 loaded; muscle; model ... See more keywords
Porphyromonas gingivalis Promotes the Proliferation and Migration of Esophageal Squamous Cell Carcinoma through the miR-194/GRHL3/PTEN/Akt Axis.
Sign Up to like & getrecommendations! Published in 2020 at "ACS infectious diseases"
DOI: 10.1021/acsinfecdis.0c00007
Abstract: Recent studies have revealed that Porphyromonas gingivalis is closely related to the occurrence and progression of esophageal squamous cell carcinoma (ESCC). However, the underlying mechanism of P. gingivalis in ESCC has not been well elucidated.… read more here.
Keywords: grhl3 pten; porphyromonas gingivalis; migration; cell ... See more keywords
MicroRNA-194-5p Levels Decrease during Deep Hypothermic Circulatory Arrest
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-32426-x
Abstract: Hypothermia has been reported to be effective in protecting the brain in various clinical conditions, including resuscitation after cardiac arrest and complex cardiovascular surgery, and is considered to be a promising therapy for stroke. The… read more here.
Keywords: circulatory arrest; arrest; mir 194; deep hypothermia ... See more keywords