MiR‐195 and miR‐497 suppress tumorigenesis in lung cancer by inhibiting SMURF2‐induced TGF‐β receptor I ubiquitination
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DOI: 10.1002/1878-0261.12581
Abstract: SMURF2 is a member of the HECT family of E3 ubiquitin ligases that have important roles as a negative regulator of transforming growth factor‐β (TGF‐β) signaling through ubiquitin‐mediated degradation of TGF‐β receptor I. However, the… read more here.
Keywords: 195 mir; mir 195; mir 497; smurf2 ... See more keywords
lncRNA‐ATB promotes viability, migration, and angiogenesis in human microvascular endothelial cells by sponging microRNA‐195
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.28692
Abstract: The atherosclerosis in the arterial system of the extremities is considered as the major pathogenesis of peripheral arterial disease. The present work aimed to explore the potential role of long noncoding RNA activated by tumor… read more here.
Keywords: mir 195; viability migration; lncrna atb; endothelial cells ... See more keywords
Isoliquiritigenin downregulates miR-195 and attenuates oxidative stress and inflammation in STZ-induced retinal injury
Sign Up to like & getrecommendations! Published in 2020 at "Naunyn-Schmiedeberg's Archives of Pharmacology"
DOI: 10.1007/s00210-020-01948-5
Abstract: Diabetic retinopathy (DR) is a major microvascular complication of diabetes mellitus that leads to significant vision loss. Isoliquiritigenin (ISL) is a bioactive flavonoid found in the root of licorice with reported anti-oxidant and anti-inflammatory activities.… read more here.
Keywords: retinal injury; mir 195; induced retinal; oxidative stress ... See more keywords
Inhibition of MicroRNA-195 Alleviates Neuropathic Pain by Targeting Patched1 and Inhibiting SHH Signaling Pathway Activation
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DOI: 10.1007/s11064-019-02797-2
Abstract: Trigeminal neuralgia (TN) is a type of chronic neuropathic pain that is caused by peripheral nerve lesions that result from various conditions, including the compression of vessels, tumors and viral infections. MicroRNAs (miRs) are increasingly… read more here.
Keywords: mir 195; patched1; signaling pathway; neuropathic pain ... See more keywords
LncRNA DDX11-AS1 accelerates hepatocellular carcinoma progression via the miR-195-5p/MACC1 pathway.
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DOI: 10.1016/j.aohep.2020.09.003
Abstract: INTRODUCTION AND AIM Long non-coding RNA (lncRNA) has been shown to be a vital regulator of cancer progression, including hepatocellular carcinoma (HCC). However, the role of DEAD/H box protein 11 antisense RNA 1 (DDX11-AS1) in… read more here.
Keywords: ddx11 as1; mir 195; hcc; progression ... See more keywords
SP1-induced upregulation of lncRNA CTBP1-AS2 accelerates the hepatocellular carcinoma tumorigenesis through targeting CEP55 via sponging miR-195-5p.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.09.080
Abstract: As reported in many research, LncRNA CTBP1 divergent transcript (CTBP1-AS2) remarkably affects the progression of several tumors. However, the precise role and function of CTBP1-AS2 in hepatocellular carcinoma (HCC) remained unknown. We found that CTBP1-AS2… read more here.
Keywords: mir 195; hcc; lncrna ctbp1; ctbp1 ... See more keywords
MicroRNA profiling of second trimester maternal plasma shows upregulation of miR-195-5p in patients with gestational diabetes.
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DOI: 10.1016/j.gene.2018.06.004
Abstract: Gestational diabetes (GDM) is defined as glucose intolerance that presents during pregnancy. It increases the risk of developing diabetes later in life. Recent studies indicate the important role of microRNAs (miRNAs) in the pathogenesis of… read more here.
Keywords: gestational diabetes; mir 195; plasma; second trimester ... See more keywords
Upregulation of microRNA-195 ameliorates calcific aortic valve disease by inhibiting VWF via suppression of the p38-MAPK signaling pathway.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of cardiology"
DOI: 10.1016/j.ijcard.2020.01.001
Abstract: BACKGROUND Growing evidence has indicated that microRNAs (miRNAs) are involved in the progression of calcific aortic valve disease (CAVD), a progressive pathological condition with no effective pharmacological therapy. This study was set out with the… read more here.
Keywords: p38 mapk; mir 195; aortic valve; mapk signaling ... See more keywords
Role of miR‐195 in cigarette smoke‐induced chronic obstructive pulmonary disease
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DOI: 10.1016/j.intimp.2017.11.030
Abstract: ABSTRACT Chronic obstructive pulmonary disease (COPD) is regarded as a persistent respiratory symptom, mainly caused by cigarette smoking. Recent data have suggested that some miRNAs are involved in the pathogenesis of COPD. Here, we found… read more here.
Keywords: chronic obstructive; mir 195; cigarette smoke; obstructive pulmonary ... See more keywords
Down-regulated microRNA-195-5p and up-regulated CXCR4 attenuates the heart function injury of heart failure mice via inactivating JAK/STAT pathway.
Sign Up to like & getrecommendations! Published in 2020 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2020.106225
Abstract: OBJECTIVE Little is known regarding the functional role of microRNA-195-5p (miR-195-5p) in heart failure (HF). Hence, the aim of the present study was to investigate the effect of miR-195-5p on cardiac function in mice with… read more here.
Keywords: mir 195; heart; 195 regulated; mice ... See more keywords
LncRNA MALAT1 promotes tumorigenesis and immune escape of diffuse large B cell lymphoma by sponging miR-195.
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DOI: 10.1016/j.lfs.2019.03.040
Abstract: BACKGROUND PD-L1 enhanced the tumorigenesis and immune escape abilities of cancers. The upstream mechanisms of PD-L1 in regulating tumorigenesis and immune escape of diffuse large B cell lymphoma (DLBCL) remained unclear. METHODS Human DLBCL cell… read more here.
Keywords: mir 195; tumorigenesis immune; malat1; immune escape ... See more keywords