The lncRNA H19 Mediates Pulmonary Fibrosis by Regulating the miR-196a/COL1A1 Axis
Sign Up to like & getrecommendations! Published in 2018 at "Inflammation"
DOI: 10.1007/s10753-018-0744-4
Abstract: Idiopathic pulmonary fibrosis (IPF) is characterized by lung fibroblasts accumulation and extracellular matrix (ECM) deposition. Recently, long-noncoding RNAs (lncRNAs) have emerged as critical regulators and prognostic markers in several diseases including IPF. In the present… read more here.
Keywords: fibrosis; col1a1; lncrna h19; mir 196a ... See more keywords
Long non-coding RNA NEAT1 functions as a competing endogenous RNA to regulate S100A9 expression by sponging miR-196a-5p in rosacea.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of dermatological science"
DOI: 10.1016/j.jdermsci.2021.02.005
Abstract: BACKGROUND Rosacea is a complex, chronic, and recurrent dermatologic condition that adversely affects quality of life and self-esteem. However, clinical relevance and molecular mechanisms underlying NEAT1 influence in rosacea remain unclear. OBJECTIVE The present study… read more here.
Keywords: s100a9 expression; rosacea; rna; mir 196a ... See more keywords
Characterizing methylation regulated miRNA in carcinoma of the human uterine cervix.
Sign Up to like & getrecommendations! Published in 2019 at "Life sciences"
DOI: 10.1016/j.lfs.2019.116668
Abstract: Gene regulatory mechanisms determine the multistep carcinogenesis process. Two aspects of epigenetics are microRNA (miRNAs) and DNA methylation that regulate distinct biological mechanisms such as metastasis, apoptosis cell proliferation and induction of senescence. Although critical,… read more here.
Keywords: methylation; mir 196a; mir 375; 375 mir ... See more keywords
HDAC inhibitor suppresses proliferation and tumorigenicity of drug‐resistant chronic myeloid leukemia stem cells through regulation of hsa‐miR‐196a targeting BCR/ABL1
Sign Up to like & getrecommendations! Published in 2018 at "Experimental Cell Research"
DOI: 10.1016/j.yexcr.2018.07.017
Abstract: &NA; Failure to eradicate hematologic cancer stem cells (hCSCs) associated with resistance to tyrosine kinase inhibitors such as imatinib mesylate (IM) in chronic myeloid leukemia (CML) patients is a clinical challenge that highlights the need… read more here.
Keywords: cd34 cd38; hsa mir; mir 196a; cd38 ... See more keywords
LncRNA-IQCH-AS1 sensitizes thyroid cancer cells to doxorubicin via modulating the miR-196a-5p/PPP2R1B signalling pathway.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of chemotherapy"
DOI: 10.1080/1120009x.2022.2082348
Abstract: Thyroid cancer is a prevalent human endocrine tumour. Surgical resection is a primary approach for well-differentiated thyroid cancers. Currently, the combination of chemotherapy with subsequent irradiation is a therapeutic strategy for the late stage or… read more here.
Keywords: mir 196a; thyroid cancer; iqch as1; cancer ... See more keywords
Exosomes from bone marrow mesenchymal stem cells promoted osteogenic differentiation by delivering miR-196a that targeted Dickkopf-1 to activate Wnt/β-catenin pathway.
Sign Up to like & getrecommendations! Published in 2021 at "Bioengineered"
DOI: 10.1080/21655979.2021.1996015
Abstract: Osteoporosis is the most common bone metabolic disease. Emerging evidence suggests that exosomes are secreted by diverse cells such as bone marrow mesenchymal stem cells (BMSCs), and play important role in cell-to-cell communication and tissue… read more here.
Keywords: wnt catenin; catenin pathway; differentiation; mir 196a ... See more keywords
miR-196a Promotes Proliferation and Inhibits Apoptosis of Immature Porcine Sertoli Cells.
Sign Up to like & getrecommendations! Published in 2019 at "DNA and cell biology"
DOI: 10.1089/dna.2018.4387
Abstract: Our previous study showed that the expression of miR-196a was significantly higher in immature porcine testes than in mature porcine testes. However, the role of miR-196a in immature Sertoli cells remains unclear. In this study,… read more here.
Keywords: sertoli cells; immature sertoli; mir 196a; apoptosis ... See more keywords
LncRNA NEAT1 promotes colorectal cancer cell proliferation and migration via regulating glial cell-derived neurotrophic factor by sponging miR-196a-5p
Sign Up to like & getrecommendations! Published in 2018 at "Acta Biochimica et Biophysica Sinica"
DOI: 10.1093/abbs/gmy130
Abstract: Colorectal cancer (CRC) is the one of the most common malignant tumors worldwide. Recent years, widespread long non-coding RNAs (lncRNAs) have been discovered and are known to regulate gene expression in cancers. However, the roles… read more here.
Keywords: proliferation migration; cell proliferation; neat1; mir 196a ... See more keywords
PO-357 miR-145–5 p, miR-196a-5p, miR-222–3 p and lncRNA MALAT1 as non-invasive markers in advanced laryngeal squamous cell carcinoma
Sign Up to like & getrecommendations! Published in 2018 at "ESMO Open"
DOI: 10.1136/esmoopen-2018-eacr25.869
Abstract: Introduction Non-coding RNAs are become one of the most investigated biomarkers in non-invasive diagnostics of cancer diseases. In this study we explore the potential of three miRNAs and one lncRNA as biomarkers in advanced laryngeal… read more here.
Keywords: mir 145; mir; mir 196a; malat1 ... See more keywords
LncRNA SNHG3 promotes cell growth by sponging miR-196a-5p and indicates the poor survival in osteosarcoma
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Immunopathology and Pharmacology"
DOI: 10.1177/2058738418820743
Abstract: Abnormal expression of long noncoding RNAs (lncRNAs) is closely associated with the pathogenesis of multiple malignancies, and lncRNA small nucleolar RNA host genes (SNHGs) play critical roles in tumor progression. However, the mechanism by which… read more here.
Keywords: mir 196a; snhg3; cell growth; expression ... See more keywords
Estrogen-induced miR-196a elevation promotes tumor growth and metastasis via targeting SPRED1 in breast cancer
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Cancer"
DOI: 10.1186/s12943-018-0830-0
Abstract: BackgroundEstrogen plays a critical role in breast cancer (BC) progression through estrogen receptor (ER)-mediated gene regulation. Emerging studies suggest that the malignant progress of BC cells is influenced by the cross talk between microRNAs (miRNAs)… read more here.
Keywords: breast cancer; estrogen; mir 196a; estrogen induced ... See more keywords