Hsa_circ_001988 attenuates GC progression in vitro and in vivo via sponging miR‐197‐3p
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.29888
Abstract: Hsa_circ_001988 has been identified as a tumor suppressor gene in several carcinomas. However, its expression pattern and role in gastric cancer (GC) have still remained elusive. This study aimed to explore the functions of hsa_circ_001988… read more here.
Keywords: hsa circ; circ 001988; eif4a3 u2af65; mir 197 ... See more keywords
MiR-197-3p reduces bortezomib resistance in multiple myeloma by inhibiting IL-6 expression in a MEAF6-dependent manner.
Sign Up to like & getrecommendations! Published in 2022 at "Leukemia research"
DOI: 10.1016/j.leukres.2022.106785
Abstract: OBJECTIVE This study investigated the mechanism by which miR-197-3p regulated IL-6 expression and reduced bortezomib (BTZ) resistance in multiple myeloma (MM). METHODS The expression of miR-197-3p, MEAF6 and IL-6 in BTZ-resistant MM cells was measured.… read more here.
Keywords: expression; resistance multiple; multiple myeloma; mir 197 ... See more keywords
Large-Scale Proteomic Identification of Targets of Cellular miR-197 Downregulated by Enterovirus A71.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.8b00762
Abstract: MicroRNAs are noncoding RNA species comprising 18-23 nucleotides that regulate host-virus interaction networks. Here, we show that enterovirus A71 infection in human rhabdomyosarcoma (RD) is regulated by miR-197 expression. Transfection of miR-197 mimic into RD… read more here.
Keywords: enterovirus a71; large scale; scale proteomic; mir 197 ... See more keywords
MicroRNA-197 controls ADAM10 expression to mediate MeCP2’s role in the differentiation of neuronal progenitors
Sign Up to like & getrecommendations! Published in 2018 at "Cell Death and Differentiation"
DOI: 10.1038/s41418-018-0257-6
Abstract: Duplication of MECP2 (Methyl-CpG-binding protein 2) causes severe mental illness called MECP2 duplication syndrome (MDS), yet the underlying mechanism remains elusive. Here we show, in Tg(MECP2) transgenic mouse brain or cultured neural progenitor cells (NPCs),… read more here.
Keywords: npc differentiation; mecp2; expression; mir 197 ... See more keywords
Familial Mediterranean fever-related miR-197-3p targets IL1R1 gene and modulates inflammation in monocytes and synovial fibroblasts
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-020-80097-4
Abstract: Familial Mediterranean fever (FMF); is an autosomal recessively inherited autoinflammatory disease caused by the mutations in the Mediterranean Fever ( MEFV ) gene. Recent studies have shown that epigenetic control mechanisms, particularly non-coding RNAs, may… read more here.
Keywords: il1r1 gene; familial mediterranean; mir 197; synovial fibroblasts ... See more keywords
Circulating microRNA-197-3p as a potential biomarker for asbestos exposure
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-03189-9
Abstract: Asbestos is considered the main cause of diseases in workers exposed to this mineral in the workplace as well as an environmental pollutant. The association between asbestos and the onset of different diseases has been… read more here.
Keywords: asbestos exposure; exposure; potential biomarker; biomarker asbestos ... See more keywords
Circular RNA ZNF609 functions as a competing endogenous RNA in regulating E2F transcription factor 6 through competitively binding to microRNA-197-3p to promote the progression of cervical cancer progression
Sign Up to like & getrecommendations! Published in 2021 at "Bioengineered"
DOI: 10.1080/21655979.2021.1896116
Abstract: ABSTRACT Countless studies have demonstrated that Circular RNAs (circRNAs) exert vital effects in regulating tumorigenesis of various cancers. CircRNA ZNF609 (circ-ZNF609) has been reported as an oncogene in various human cancers. Nevertheless, its regulating effect… read more here.
Keywords: rna; cervical cancer; circ znf609; mir 197 ... See more keywords
Regulation of microRNA miR-197-3p/CDC28 protein kinase regulatory subunit 1B (CKS1B) axis by Circular RNA hsa_circ_0000285 promotes glioma progression
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2022.2031673
Abstract: ABSTRACT Circular RNA circ_0000285 is differentially expressed in several malignancies; however, its role in gliomas is under investigation. Reverse transcription quantitative polymerase chain reaction was conducted to evaluate the expression of circ_0000285, miR-197-3p, and CDC28… read more here.
Keywords: circ 0000285; rna; mir 197; cks1b ... See more keywords
LncRNA MYMLR promotes pituitary adenoma development by upregulating carbonyl reductase 1 via sponging miR-197-3p
Sign Up to like & getrecommendations! Published in 2022 at "Anti-Cancer Drugs"
DOI: 10.1097/cad.0000000000001385
Abstract: Long noncoding RNAs (lncRNAs) have been demonstrated to participate in various biological processes and play key roles in tumorigenesis and metastasis. Pituitary adenoma (PA) is one of the most common malignancies in central nervous system.… read more here.
Keywords: pituitary adenoma; development; carbonyl reductase; mir 197 ... See more keywords
IL6R is a target of miR‐197 in human keratinocytes
Sign Up to like & getrecommendations! Published in 2020 at "Experimental Dermatology"
DOI: 10.1111/exd.14169
Abstract: Psoriasis is a chronic inflammatory disorder with cutaneous and systemic manifestations and substantial negative effects on patients’ quality of life. MicroRNAs (miRNAs) are post‐transcriptional regulators of gene expression that play a role in the pathogenesis… read more here.
Keywords: psoriasis; targets mir; target mir; mir 197 ... See more keywords
miR-197 Participates in Lipopolysaccharide-Induced Cardiomyocyte Injury by Modulating SIRT1
Sign Up to like & getrecommendations! Published in 2022 at "Cardiology Research and Practice"
DOI: 10.1155/2022/7687154
Abstract: Sepsis is a systemic inflammation and is capable of inducing myocarditis, which is a major leading cause of death in patients. Studies have found that miR-197 is correlated with the prognosis of patients with inflammatory… read more here.
Keywords: h9c2 cells; cardiomyocyte injury; mir 197; induced cardiomyocyte ... See more keywords