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   Articles with "mir 199a" as a keyword



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LncRNA TMPO‐AS1 serves as a ceRNA to promote osteosarcoma tumorigenesis by regulating miR‐199a‐5p/WNT7B axis

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recommendations! Published in 2019 at "Journal of Cellular Biochemistry"

DOI: 10.1002/jcb.29451

Abstract: Osteosarcoma (OS) is a common kind of aggressive tumor in bone which was mostly identified in children and adolescents with extremely high risk of death. Accumulating research works have displayed that long noncoding RNAs (lncRNAs)… read more here.

Keywords: mir 199a; wnt7b; tmpo as1; as1 serves ... See more keywords
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MiR‐199a‐3p inhibition facilitates cardiomyocyte differentiation of embryonic stem cell through promotion of MEF2C

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recommendations! Published in 2019 at "Journal of Cellular Physiology"

DOI: 10.1002/jcp.28899

Abstract: MicroRNAs (miRNAs) is a small molecule (19–25 nucleotide) noncoding RNA that inhibits the expression of target messenger RNA (mRNA) at the posttranscriptional level as an endogenous regulator. There is an increasing evidence that miR‐199a‐3p has… read more here.

Keywords: stem cell; mir 199a; mef2c; differentiation ... See more keywords
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MiR-199a suppresses prostate cancer paclitaxel resistance by targeting YES1

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recommendations! Published in 2017 at "World Journal of Urology"

DOI: 10.1007/s00345-017-2143-0

Abstract: PurposeProstate cancer chemoresistance is a major contributor to the poor survival of patients. MicroRNAs (miRNAs) play an important role in regulating cancer resistance. Here we aim to explore the role and mechanism of miR-199a in… read more here.

Keywords: ptx resistance; mir 199a; resistance; prostate cancer ... See more keywords
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MiR-199a-3p Restrains Foaming and Inflammation by Regulating RUNX1 in Macrophages

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recommendations! Published in 2022 at "Molecular Biotechnology"

DOI: 10.1007/s12033-022-00484-2

Abstract: MiR-199a-3p was reported decreased in serum of coronary heart disease patients and human atherosclerotic plaques. This study aims to investigate the roles of miR-199a-3p in atherosclerosis (AS). AS was induced in ApoE−/− mice via high… read more here.

Keywords: mir 199a; raw264 cells; ldl induced; runx1 ... See more keywords
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Exosomal miR-199a-5p promotes hepatic lipid accumulation by modulating MST1 expression and fatty acid metabolism

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recommendations! Published in 2020 at "Hepatology International"

DOI: 10.1007/s12072-020-10096-0

Abstract: Non-alcoholic fatty liver disease (NAFLD) and its complications has become an expanding health problem worldwide with limited therapeutic approaches. The current study was aiming to identify novel microRNA in the regulation of hepatic lipid metabolism… read more here.

Keywords: hepatic lipid; metabolism; lipid accumulation; mir 199a ... See more keywords

SNHG1 lncRNA negatively regulates miR-199a-3p to enhance CDK7 expression and promote cell proliferation in prostate cancer.

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recommendations! Published in 2017 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2017.03.169

Abstract: Long noncoding RNAs (lncRNAs) have been reported to play vital roles in the development of human cancers, but our understandings of most lncRNAs in cancers are still limited. Recently, accumlating evidences have showed that many… read more here.

Keywords: prostate; cdk7; mir 199a; prostate cancer ... See more keywords
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lncRNA-Map2k4 sequesters miR-199a to promote FGF1 expression and spinal cord neuron growth.

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recommendations! Published in 2017 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2017.06.145

Abstract: Spinal cord injury (SCI) is a common critical illness in clinical practice. SCI prevention, treatment and rehabilitation have become important topics in today's medical profession. Studies have shown that long noncoding RNAs (lncRNAs) also play… read more here.

Keywords: lncrna map2k4; mir 199a; fgf1 expression;
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Nanofibrous spongy microspheres to deliver rabbit mesenchymal stem cells and anti-miR-199a to regenerate nucleus pulposus and prevent calcification.

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recommendations! Published in 2020 at "Biomaterials"

DOI: 10.1016/j.biomaterials.2020.120213

Abstract: Lower back pain is mainly caused by intervertebral disc degeneration, in which calcification is frequently involved. Here novel nanofibrous spongy microspheres (NF-SMS) are used to carry rabbit bone marrow mesenchymal stromal cells (MSCs) to regenerate… read more here.

Keywords: anti mir; mir 199a; calcification; rabbit ... See more keywords
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Common Regulatory Pathways Mediate Activity of MicroRNAs Inducing Cardiomyocyte Proliferation

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recommendations! Published in 2019 at "Cell Reports"

DOI: 10.1016/j.celrep.2019.05.005

Abstract: Summary Loss of functional cardiomyocytes is a major determinant of heart failure after myocardial infarction. Previous high throughput screening studies have identified a few microRNAs (miRNAs) that can induce cardiomyocyte proliferation and stimulate cardiac regeneration… read more here.

Keywords: common regulatory; mir 199a; cardiomyocyte proliferation; proliferation ... See more keywords
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Identification of key genes in cleft lip with or without cleft palate regulated by miR-199a-5p.

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recommendations! Published in 2018 at "International journal of pediatric otorhinolaryngology"

DOI: 10.1016/j.ijporl.2018.06.005

Abstract: BACKGROUND Cleft lip with or without cleft palate (CL/P) is one of the most common congenital defects, which etiology involves both genetic and environmental factors. Previous studies have shown that miR-199a-5p may mediate the occurrence… read more here.

Keywords: target genes; lip without; mir 199a; target ... See more keywords
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Whole genome miRNA profiling revealed miR-199a as potential placental pathogenesis of selective fetal growth restriction in monochorionic twin pregnancies.

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recommendations! Published in 2020 at "Placenta"

DOI: 10.1016/j.placenta.2020.02.002

Abstract: INTRODUCTION Placental-related mechanism of fetal growth restriction (FGR) is still unknown. Here we aimed to profile whole-genome miRNA between selective FGR twin (sFGR-T) and normally larger co-twin (sL-T) in monochorionic (MC) twin pregnancies and to… read more here.

Keywords: mirna; mir 199a; twin pairs; sfgr ... See more keywords