Knockdown of miR-19a suppresses gastrointestinal dysmotility diarrhea after TBI by regulating VIP expression.
Sign Up to like & getrecommendations! Published in 2023 at "Brain and behavior"
DOI: 10.1002/brb3.3071
Abstract: BACKGROUND AND AIMS Traumatic brain injury (TBI) is the main cause of death and can lead to a variety of physiological complications, including gastrointestinal dysfunction. The present study aimed to confirm the miR-19a-mediated suppression of… read more here.
Keywords: mir 19a; diarrhea tbi; tbi; vip expression ... See more keywords
Signal pathways, diseases, and functions associated with the miR‐19a/92a cluster and the use of berberine to modulate the expression of this cluster in multiple myeloma cells
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.22057
Abstract: Berberine downregulated miR‐19a/92a cluster expression in multiple myeloma (MM) cells. read more here.
Keywords: 19a 92a; cluster; multiple myeloma; myeloma cells ... See more keywords
HDAC3 Downregulation Improves Cerebral Ischemic Injury via Regulation of the SDC1-Dependent JAK1/STAT3 Signaling Pathway Through miR-19a Upregulation.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular neurobiology"
DOI: 10.1007/s12035-021-02325-w
Abstract: Histone deacetylase (HDAC) inhibitors can protect the brain from ischemic injury. This study aimed to identify the regulation of HDAC3 in cerebral ischemic injury. Middle cerebral artery occlusion (MCAO) was performed to establish a mouse… read more here.
Keywords: ischemic injury; jak1 stat3; mir 19a; hdac3 ... See more keywords
miR-19b is elevated in peripheral blood of schizophrenic patients and attenuates proliferation of hippocampal neural progenitor cells.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of psychiatric research"
DOI: 10.1016/j.jpsychires.2020.09.006
Abstract: MicroRNAs (miRNAs) have been investigated in neurodevelopmental and psychiatric disorders including schizophrenia (SZ). Previous studies showed miRNAs dysregulation in postmortem brain tissues and peripheral blood of SZ patients. These suggest that miRNAs may play a… read more here.
Keywords: mir 19b; mir 19a; peripheral blood; proliferation ... See more keywords
CircFN1 upregulation initiated oxidative stress-induced apoptosis and inhibition of proliferation and migration in trophoblasts via circFN1-miR-19a/b-3p-ATF2 ceRNA network.
Sign Up to like & getrecommendations! Published in 2022 at "Reproductive biology"
DOI: 10.1016/j.repbio.2022.100631
Abstract: Recently, the etiopathogenesis of preeclampsia (PE) has been developed from the perspective of circular RNA, microRNA and their crosstalk in placental oxidative stress. Real-time quantitative PCR and western blotting detected expression of circular RNA-fibronectin 1… read more here.
Keywords: circfn1; apoptosis; oxidative stress; mir 19a ... See more keywords
MiR-19a/miR-96-mediated low expression of KIF26A suppresses metastasis by regulating FAK pathway in gastric cancer
Sign Up to like & getrecommendations! Published in 2021 at "Oncogene"
DOI: 10.1038/s41388-020-01610-7
Abstract: Gastric cancer (GC) is one of the most common malignant neoplasms. Invasion and metastasis are the main causes of GC-related deaths. Recently, kinesins were discovered to be involved in tumor development. The aim of this… read more here.
Keywords: focal adhesion; gastric cancer; metastasis; kif26a ... See more keywords
Overexpressed RBPMS-AS1 increased cell radiosensitivity by sponging miR-19a-3p in lung cancer cell lines (A549 and SK-MES-1) via regulating PTEN/AKT axis.
Sign Up to like & getrecommendations! Published in 2023 at "International journal of radiation biology"
DOI: 10.1080/09553002.2023.2181997
Abstract: PURPOSE This paper intended to study RBPMS-AS1 in lung cancer (LC) radiosensitivity. MATERIALS AND METHODS LC cells were transfected with RBPMS-AS1 overexpression plasmid and miR-19a-3p mimic and treated with radiation. PTEN, AKT, p-AKT, RBPMS-AS1 and… read more here.
Keywords: rbpms as1; cell; mir 19a; overexpressed rbpms ... See more keywords
Pleckstrin homology-like domain family A, member 3, a miR-19a-3p-regulated gene, suppresses tumor growth in osteosarcoma by downregulating the Akt pathway
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2022.2031404
Abstract: ABSTRACT Pleckstrin homology-like domain family A, member 3 (PHLDA3), is emerging as a critical regulator for multiple cancers. Nevertheless, the expression and role of PHLDA3 in osteosarcoma remain unknown. Herein, we purposed to elucidate the… read more here.
Keywords: homology like; osteosarcoma; mir 19a; pleckstrin homology ... See more keywords
MiR-19a suppresses ferroptosis of colorectal cancer cells by targeting IREB2
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2022.2054194
Abstract: ABSTRACT Colorectal cancer (CRC) is the most common malignant tumor occurred in digestive system. However, the prognosis of CRC patients is poor. Therefore, it is urgent to illuminate the mechanism suppressing CRC and explore novel… read more here.
Keywords: mir 19a; 19a suppresses; crc; colorectal cancer ... See more keywords
Dysregulated LINC00961 Contributes to the Vitality and Migration of NSCLC Via miR-19a-3p/miR-19b-3p/miR-125b-5p.
Sign Up to like & getrecommendations! Published in 2022 at "DNA and cell biology"
DOI: 10.1089/dna.2021.0900
Abstract: Accumulating evidence implies that long noncoding RNAs participate in non-small cell lung cancer (NSCLC) tumorigenesis. Our current study synthetically analyzed RNA sequencing data downloaded from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO)… read more here.
Keywords: mir 19a; 19a mir; 19b mir; linc00961 ... See more keywords
Hyperoside alleviates postmenopausal osteoporosis via regulating miR-19a-5p/IL-17A axis.
Sign Up to like & getrecommendations! Published in 2023 at "American journal of reproductive immunology"
DOI: 10.1111/aji.13709
Abstract: PROBLEM Postmenopausal osteoporosis (PMO) is a common osteoporosis. Hyperoside (Hyp), a natural flavonoid compound, has anti-osteoporotic effects, but the underlying mechanisms remain poorly understood. Inflammatory cytokine IL-17A is upregulated in PMO and plays vital roles… read more here.
Keywords: mir 19a; 19a 17a; pmo; 17a axis ... See more keywords