Exosomal microRNAs as tumor markers in epithelial ovarian cancer
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Oncology"
DOI: 10.1002/1878-0261.12371
Abstract: Specific microRNAs (miRNAs) are packaged in exosomes that regulate processes in tumor development and progression. The current study focuses on the influence of exosomal miRNAs in the pathogenesis of epithelial ovarian cancer (EOC). MiRNA profiles… read more here.
Keywords: epithelial ovarian; mir; mir 200b; ovarian cancer ... See more keywords
Hepatocyte nuclear factor‐1β suppresses the stemness and migration of colorectal cancer cells through promoting miR‐200b activity
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.23229
Abstract: The effects of hepatocyte nuclear factors (HNFs) have been established in various tumors; however, the roles of HNF‐1β in colorectal cancer progression are never been found. In the present study, HNF‐1β expression was initially detected… read more here.
Keywords: stemness migration; colorectal cancer; cancer cells; mir 200b ... See more keywords
MiR-200b attenuates IL-6 production through IKKβ and ZEB1 in human gingival fibroblasts
Sign Up to like & getrecommendations! Published in 2018 at "Inflammation Research"
DOI: 10.1007/s00011-018-1192-1
Abstract: ObjectiveMicroRNAs (miRNAs) play important roles in biological processes such as cell differentiation, development, infection, immune response, inflammation and tumorigenesis. We previously reported that the expression of miR-200b was significantly increased in inflamed gingiva compared with… read more here.
Keywords: gingival fibroblasts; mir 200b; ikk; ikk zeb1 ... See more keywords
Tenascin C is dysregulated in hypoplastic lungs of miR-200b−/− mice
Sign Up to like & getrecommendations! Published in 2022 at "Pediatric Surgery International"
DOI: 10.1007/s00383-022-05096-0
Abstract: We previously demonstrated that absence of miR-200b results in abnormal lung development in congenital diaphragmatic hernia due to imbalance between epithelial and mesenchymal cells. Tenascin C is a highly conserved extracellular matrix protein involved in… read more here.
Keywords: tenascin; lung; lungs mir; mir 200b ... See more keywords
MicroRNA profiling identifies Forkhead transcription factor M1 (FOXM1) regulated miR-186 and miR-200b alterations in triple negative breast cancer.
Sign Up to like & getrecommendations! Published in 2021 at "Cellular signalling"
DOI: 10.1016/j.cellsig.2021.109979
Abstract: Breast cancer (BC) is the most commonly diagnosed malignancy. MicroRNAs (miRNAs) play important roles in the tumorigenesis, metastasis and progression of BC. Forkhead Box M1 (FOXM1) oncogenic transcription factor is involved in events considered as… read more here.
Keywords: foxm1; mir 200b; breast cancer; cancer ... See more keywords
LncRNA-SNHG29 inhibits vascular smooth muscle cell calcification by downregulating miR-200b-3p to activate the α-Klotho/FGFR1/FGF23 axis.
Sign Up to like & getrecommendations! Published in 2020 at "Cytokine"
DOI: 10.1016/j.cyto.2020.155243
Abstract: BACKGROUND Vascular calcification (VC) is characterized by mineral accumulation on the walls of arteries and veins, which is a pathological process commonly found in elderly individuals and patients with atherosclerosis, hypertension, and diabetes. Emerging evidence… read more here.
Keywords: snhg29; calcification; mir 200b; fgfr1 fgf23 ... See more keywords
miR-200b downregulates Kruppel Like Factor 2 (KLF2) during acute hypoxia in human endothelial cells.
Sign Up to like & getrecommendations! Published in 2017 at "European journal of cell biology"
DOI: 10.1016/j.ejcb.2017.10.001
Abstract: The role of microRNAs in controlling angiogenesis is recognized as a promising therapeutic target in both cancer and cardiovascular disorders. However, understanding a miRNA's pleiotropic effects on angiogenesis is a limiting factor for these types… read more here.
Keywords: human endothelial; mir 200b; endothelial cells; hypoxia ... See more keywords
Down-regulation of microRNA-200b is a potential prognostic marker of lung cancer in southern-central Chinese population
Sign Up to like & getrecommendations! Published in 2019 at "Saudi Journal of Biological Sciences"
DOI: 10.1016/j.sjbs.2018.08.023
Abstract: MicroRNAs (miRNAs) may regulate diverse biological processes and play an important role in cancer. And MiRNAs have been proposed as a useful tool for lung cancer diagnosis and therapeutics in cancer. The purpose of the… read more here.
Keywords: cancer; mir 200b; 200b expression; lung cancer ... See more keywords
The miR‐200b/200a/429 cluster prevents metastasis and induces dormancy in a murine claudin‐low mammary tumor cell line
Sign Up to like & getrecommendations! Published in 2018 at "Experimental Cell Research"
DOI: 10.1016/j.yexcr.2018.04.024
Abstract: ABSTRACT The miR‐200 family of microRNAs consisting of miR‐141, miR‐200a, miR‐200b, miR‐200c and miR‐429 are emerging as important regulators of breast cancer progression. This family of microRNAs maintain mammary epithelial identity and downregulation of miR‐200… read more here.
Keywords: tumor; 429 cluster; mir 200b; 200a 429 ... See more keywords
Decreased miR-200b-3p in cancer cells leads to angiogenesis in HCC by enhancing endothelial ERG expression
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-67425-4
Abstract: Transcription factor ERG (erythroblast transformation-specific (ETS)-related gene) is essential in endothelial differentiation and angiogenesis, in which microRNA (miR)-200b-3p targeting site is expected by miRNA target prediction database. miR-200b is known decreased in hepatocellular carcinoma (HCC),… read more here.
Keywords: hcc; endothelial erg; mir 200b; hcc tissues ... See more keywords
TGF-β1 Induces Human Tenon’s Fibroblasts Fibrosis via miR-200b and Its Suppression of PTEN Signaling
Sign Up to like & getrecommendations! Published in 2019 at "Current Eye Research"
DOI: 10.1080/02713683.2018.1549261
Abstract: ABSTRACT Background: To determine the involvement of MicroRNA-200b (miR-200b) in human Tenon’s fibroblasts (HTFs) fibrosis. Methods: HTFs were treated with 10 ng/ml TGF-β1 for 24 h. Expression of α-smooth muscle actin (α-SMA), Fibronectin and Collagen1A1… read more here.
Keywords: mir; human tenon; mir 200b; pten signaling ... See more keywords