The long noncoding RNA NORAD enhances the TGF‐β pathway to promote hepatocellular carcinoma progression by targeting miR‐202‐5p
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.27869
Abstract: Hepatocellular carcinoma (HCC) is one of the most fatal cancers with common features of invasion and metastasis. Recent evidence indicate that the long noncoding RNA NORAD is a potential oncogene and is significantly upregulated in… read more here.
Keywords: hepatocellular carcinoma; long noncoding; tgf pathway; hcc ... See more keywords
MiR-202-5p attenuates neurological deficits and neuronal injury in MCAO model rats and OGD-induced injury in Neuro-2a cells by targeting eIF4E-mediated induction of autophagy and inhibition of Akt/GSK-3β pathway.
Sign Up to like & getrecommendations! Published in 2019 at "Molecular and cellular probes"
DOI: 10.1016/j.mcp.2019.101497
Abstract: Ischemic stroke is a common cerebrovascular disease caused by insufficient blood supply to the brain. In recent years, studies have demonstrated that microRNAs (miRNAs) are involved in a variety of biological processes in the nervous… read more here.
Keywords: ogd induced; induced injury; n2a cells; mcao ... See more keywords
LncRNA MALAT1 facilitates lung metastasis of osteosarcomas through miR-202 sponging
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-69574-y
Abstract: Lungs are the primary metastatic sites for osteosarcomas responsible for associated mortality. Recent data has documented role of long non-coding RNAs (lncRNAs) in proliferation and growth of osteosarcoma cells. We evaluated a role of lncRNAs… read more here.
Keywords: malat1; metastasis; metastasis osteosarcomas; mir 202 ... See more keywords
Shikonin-mediated up-regulation of miR-34a and miR-202 inhibits retinoblastoma proliferation.
Sign Up to like & getrecommendations! Published in 2018 at "Toxicology research"
DOI: 10.1039/c8tx00079d
Abstract: Retinoblastoma (RB) is an ocular tumor that occurs mainly in children. The pathogenesis of RB is not well understood, and its treatment strategies are very limited. Shikonin is widely reported as an anti-tumor agent. However,… read more here.
Keywords: mir 34a; mir; proliferation; shikonin ... See more keywords
miR-202-3p negatively regulates MMP-1 to inhibit the proliferation, migration and invasion of lung adenocarcinoma cells
Sign Up to like & getrecommendations! Published in 2021 at "Cell Cycle"
DOI: 10.1080/15384101.2021.1876390
Abstract: ABSTRACT Lung adenocarcinoma (LUAD) is one of the common cancers. Studies show that MMP-1 is involved in tumor progression, yet relevant regulatory mechanism in LUAD remains to be further elucidated. Here, we demonstrated from bioinformatics… read more here.
Keywords: proliferation migration; luad; mmp; mir 202 ... See more keywords
Upregulated lncRNA Gm2044 inhibits male germ cell development by acting as miR-202 host gene
Sign Up to like & getrecommendations! Published in 2019 at "Animal Cells and Systems"
DOI: 10.1080/19768354.2019.1591506
Abstract: ABSTRACT Long non-coding RNAs (lncRNAs) have been found to participate in the regulation of human spermatogenic cell development. However, little is known about the abnormal expression of lncRNAs associated with spermatogenic failure and their molecular… read more here.
Keywords: lncrna gm2044; cell development; gene; mir 202 ... See more keywords
Differential Expression of miR-202 and Validation of Predicted Target Genes in the Skin Tissue of C57BL/6 Black Mice and BALB/c White Mice.
Sign Up to like & getrecommendations! Published in 2017 at "DNA and cell biology"
DOI: 10.1089/dna.2016.3613
Abstract: In recent years, with the need of the fur industry to obtain greater quantities of high-quality fur and the research of hair follicle development attracting greater attention, the role of miRNAs in hair follicle development… read more here.
Keywords: skin tissue; target; mice; mir 202 ... See more keywords
Maternal miR-202-5p is required for zebrafish primordial germ cell migration by protecting small GTPase Cdc42
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Molecular Cell Biology"
DOI: 10.1093/jmcb/mjz103
Abstract: Abstract In many lower animals, germ cell formation, migration, and maintenance depend on maternally provided determinants in germ plasm. In zebrafish, these processes have been extensively studied in terms of RNA-binding proteins and other coding… read more here.
Keywords: primordial germ; migration; pgc migration; germ cell ... See more keywords
Tetrandrine Ameliorates Myocardial Ischemia Reperfusion Injury through miR-202-5p/TRPV2
Sign Up to like & getrecommendations! Published in 2021 at "BioMed Research International"
DOI: 10.1155/2021/8870674
Abstract: Objective This study is aimed at investigating the therapeutic effects of tetrandrine (Tet) on myocardial ischemia reperfusion (I/R) injury and probe into underlying molecular mechanism. Methods H9C2 cells were divided into hypoxia/oxygenation (H/R) group, H/R+Tet… read more here.
Keywords: 202 trpv2; group; group tet; injury ... See more keywords
Long non-coding RNA NORAD promotes pancreatic cancer stem cell proliferation and self-renewal by blocking microRNA-202-5p-mediated ANP32E inhibition
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Translational Medicine"
DOI: 10.1186/s12967-021-03052-5
Abstract: Background Cancer stem cells (CSCs) are key regulators in the processes of tumor initiation, progression, and recurrence. The mechanism that maintains their stemness remains enigmatic, although the role of several long noncoding RNAs (lncRNAs) has… read more here.
Keywords: cancer stem; lncrna norad; self renewal; mir 202 ... See more keywords
MiR-202 controls female fecundity by regulating medaka oogenesis
Sign Up to like & getrecommendations! Published in 2018 at "PLoS Genetics"
DOI: 10.1371/journal.pgen.1007593
Abstract: Female gamete production relies on coordinated molecular and cellular processes that occur in the ovary throughout oogenesis. In fish, as in other vertebrates, these processes have been extensively studied both in terms of endocrine/paracrine regulation… read more here.
Keywords: oogenesis; mir 202; 202 controls; female fecundity ... See more keywords