The miR‐203/SNAI2 axis regulates prostate tumor growth, migration, angiogenesis and stemness potentially by modulating GSK‐3β/β‐CATENIN signal pathway
Sign Up to like & getrecommendations! Published in 2018 at "IUBMB Life"
DOI: 10.1002/iub.1720
Abstract: Dysregulation of microRNA expression plays a pivotal role in the initiation and progression of a variety of human carcinomas including prostate cancer. Our previous studies have demonstrated that the silence of miR‐203 contributes to the… read more here.
Keywords: 203 snai2; mir 203; prostate cancer; snai2 ... See more keywords
Upregulation of BMI1-suppressor miRNAs (miR-200c, miR-203) during terminal differentiation of colon epithelial cells
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DOI: 10.1007/s00535-022-01865-9
Abstract: MicroRNAs (miRNAs) are key regulators of stem cell functions, including self-renewal and differentiation. In this study, we aimed to identify miRNAs that are upregulated during terminal differentiation in the human colon epithelium, and elucidate their… read more here.
Keywords: mir 203; epithelial cells; mir 200c; colon ... See more keywords
LncRNA UCA1 Suppresses the Inflammation Via Modulating miR-203-Mediated Regulation of MEF2C/NF-κB Signaling Pathway in Epilepsy
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DOI: 10.1007/s11064-019-02952-9
Abstract: Although many advances have been made in the pathogenesis of epilepsy recently, the pathological mechanisms of epilepsy are still largely unknown. Exploring the pathological mechanisms and developing novel therapeutic strategies for epilepsy are urgently needed.… read more here.
Keywords: mir 203; mef2c; expression; lncrna uca1 ... See more keywords
Sevoflurane inhibits the migration and invasion of colorectal cancer cells through regulating ERK/MMP‐9 pathway by up‐regulating miR‐203
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Pharmacology"
DOI: 10.1016/j.ejphar.2019.01.025
Abstract: ABSTRACT Surgery resection is the primary treatment for colorectal cancer (CRC) patients with the risk of cancer dissemination and metastasis. Sevoflurane is one inhalational anesthesia which regulates migration and invasion in varying cancers. However, the… read more here.
Keywords: mmp pathway; mir 203; migration invasion; sevoflurane ... See more keywords
The inhibition of microRNA-203 on ischemic reperfusion injury after total knee arthroplasty via suppressing MYD88-mdiated toll-like receptor signaling pathway.
Sign Up to like & getrecommendations! Published in 2019 at "Gene"
DOI: 10.1016/j.gene.2019.02.030
Abstract: Ischemia reperfusion injury (IRI), a complex phenomenon often encountered in surgery, can lead to local and distant tissue destruction and sometimes even death. microRNA-203 (miR-203) has been reported to negatively regulate ischemia induced microglia activation… read more here.
Keywords: signaling pathway; mir 203; iri; expression ... See more keywords
Up-regulation of microRNA-203 inhibits myocardial fibrosis and oxidative stress in mice with diabetic cardiomyopathy through the inhibition of PI3K/Akt signaling pathway via PIK3CA.
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DOI: 10.1016/j.gene.2019.143995
Abstract: Diabetic cardiomyopathy (DCM) refers to the myocardial dysfunction in the absence of coronary artery disease and hypertension. Recently, the role of microRNAs (miRs) in gene expression regulation has attracted much more attention. Studies have shown… read more here.
Keywords: akt signaling; myocardial fibrosis; pi3k akt; signaling pathway ... See more keywords
Knockdown of microRNA‐203 alleviates LPS‐induced injury by targeting MCL‐1 in C28/I2 chondrocytes
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DOI: 10.1016/j.yexcr.2017.07.034
Abstract: &NA; Several microRNAs (miRs) are associated with osteoarthritis (OA) and are also functionally implicated in the pathogenesis of the disease. This study was aimed to investigate the potential roles of miR‐203 in the development and… read more here.
Keywords: targeting mcl; cell; lps induced; mir 203 ... See more keywords
COTI-2 induces cell apoptosis in pediatric acute lymphoblastic leukemia via upregulation of miR-203
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DOI: 10.1080/21655979.2020.1729927
Abstract: ABSTRACT COTI-2 is a third-generation thiosemicarbazone, which is effective against a diverse group of human cancer cell lines at nanomolar concentrations. COTI-2 also showed superior activity against tumor cells, in vitro and in vivo. As… read more here.
Keywords: coti; cell apoptosis; mir 203; jurkat cells ... See more keywords
MicroRNA-203 mediates P. gingivalis LPS-induced inflammation and differentiation of periodontal ligament cells.
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DOI: 10.1111/odi.14132
Abstract: AIM In this study, we aimed to explore the effects of microRNA-203 (miR-203) on P. gingivalis lipopolysaccharide (P.g. LPS)-stimulated periodontal ligament cells (PDLCs) and identify potential molecular targets for periodontitis treatment. METHODS PDLCs were stimulated… read more here.
Keywords: mir 203; ligament cells; lps induced; differentiation ... See more keywords
lncRNA PINK1-AS Aggravates Cerebral Ischemia/Reperfusion Oxidative Stress Injury through Regulating ATF2 by Sponging miR-203
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DOI: 10.1155/2022/1296816
Abstract: Ischemic stroke is a common disease that led to high mortality and high disability. NADPH oxidase 2- (NOX2-) mediated oxidative stress and long noncoding RNA have important roles in cerebral ischemia/reperfusion (CI/R) injury, whereas whether… read more here.
Keywords: lncrna pink1; mir 203; oxidative stress; injury ... See more keywords
Abstract 1424: Elucidating the microRNA-203 specific biological processes in glioblastoma cells from high-throughput RNA-sequencing
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Research"
DOI: 10.1158/1538-7445.am2018-1424
Abstract: Glioblastoma (GBM) is the most common primary malignant intracranial adult brain tumor. Allelic deletion on chromosome 14q play an essential role in GBM pathogenesis, and this chromosome 14q site was thought to harbor multiple tumor… read more here.
Keywords: microrna 203; throughput rna; mir 203; expression ... See more keywords