Circ_0123996 promotes the proliferation, inflammation, and fibrosis of mesangial cells by sponging miR‐203a‐3p to upregulate SOX6 in diabetic nephropathy
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23139
Abstract: Circular RNA has been reported to participate in human diseases including diabetic nephropathy (DN). However, the role and mechanism of circ_0123996 in DN need to be further explored. Relative expression levels of circ_0123996, microRNA (miR)‐203a‐3p,… read more here.
Keywords: mir 203a; proliferation inflammation; inflammation fibrosis; circ 0123996 ... See more keywords
MicroRNA-203a regulates pancreatic β cell proliferation and apoptosis by targeting IRS2.
Sign Up to like & getrecommendations! Published in 2020 at "Molecular biology reports"
DOI: 10.1007/s11033-020-05818-4
Abstract: The main pathogenesis of type 1 diabetes mellitus (T1DM) is autoimmune-mediated apoptosis of pancreatic islet β cells. We sought to characterize the function of microRNA-203a (miR-203a) on pancreatic islet β cell proliferation and apoptosis. In… read more here.
Keywords: irs2; cell proliferation; mir 203a; apoptosis ... See more keywords
MYC-Induced miR-203b-3p and miR-203a-3p Control Bcl-xL Expression and Paclitaxel Sensitivity in Tumor Cells1
Sign Up to like & getrecommendations! Published in 2019 at "Translational Oncology"
DOI: 10.1016/j.tranon.2018.10.001
Abstract: Taxanes are chemotherapeutic agents used in the treatment of solid tumors, particularly of breast, ovarian, and lung origin. However, patients show divergent therapy responses, and the molecular determinants of taxane sensitivity have remained elusive. Especially… read more here.
Keywords: mir 203a; mir 203b; 203b mir; sensitivity ... See more keywords
Host microRNA-203a Is antagonistic to the progression of foot-and-mouth disease virus infection.
Sign Up to like & getrecommendations! Published in 2017 at "Virology"
DOI: 10.1016/j.virol.2017.01.019
Abstract: Sam68 was previously shown to be a critical host factor for foot-and-mouth disease virus (FMDV) replication. MicroRNA (miR) miR-203a is reportedly a negative regulator of Sam68 expression both in vitro and in vivo. Here, transfection… read more here.
Keywords: mir 203a; mir; infection; foot mouth ... See more keywords
miR-203a-3p, ABL1 and TP63 gene expression is altered in the endometrium of women with endometriosis
Sign Up to like & getrecommendations! Published in 2022 at "Gynecological Endocrinology"
DOI: 10.1080/09513590.2022.2076830
Abstract: Abstract Objective Many genes and miRNAs have been shown to be associated with the pathogenesis of endometriosis. TP63 (p63) is implicated in lineage specification, proliferative potential, differentiation, cell death and survival. The ABL1 proto-oncogene encodes… read more here.
Keywords: endometriosis; expression; stage; abl1 tp63 ... See more keywords
MiR‐203a‐3p inhibits retinal angiogenesis and alleviates proliferative diabetic retinopathy in oxygen‐induced retinopathy (OIR) rat model via targeting VEGFA and HIF‐1α
Sign Up to like & getrecommendations! Published in 2019 at "Clinical and Experimental Pharmacology and Physiology"
DOI: 10.1111/1440-1681.13163
Abstract: Proliferative diabetic retinopathy (PDR) is a common complication of diabetes mellitus, characterized by abnormal retinal angiogenesis. MicroRNA‐203‐3p (miR‐203‐3p) was found to be down‐regulated in a murine model of proliferative retinopathy. This study was performed to… read more here.
Keywords: vegfa hif; mir 203a; retinal angiogenesis;
LncRNA HOXD-AS1 promotes oral squamous cell carcinoma by sponging miR-203a-5p.
Sign Up to like & getrecommendations! Published in 2022 at "Oral diseases"
DOI: 10.1111/odi.14152
Abstract: OBJECTIVE In the present study, we aimed to explore lncRNA HOXD cluster antisense RNA 1 (HOXD-AS1) expression in oral squamous cell carcinoma (OSCC) tissues, its biological roles, and the underlying potential mechanisms in OSCC progression.… read more here.
Keywords: hoxd as1; mir 203a; overexpression; expression ... See more keywords
Long non-coding RNA MALAT1 participates in the pathological angiogenesis of diabetic retinopathy in oxygen-induced retinopathy mouse model by sponging miR-203a-3p.
Sign Up to like & getrecommendations! Published in 2019 at "Canadian journal of physiology and pharmacology"
DOI: 10.1139/cjpp-2019-0489
Abstract: Diabetic retinopathy (DR) is a devastating complication of diabetes. The aim of the present study is to investigate the exact role and mechanism of lncRNA MALAT1 (MALAT1) in the progress of DR. Oxygen-induced retinopathy (OIR)… read more here.
Keywords: oxygen induced; mir 203a; diabetic retinopathy; induced retinopathy ... See more keywords
LncRNA GAS5 Represses Osteosarcoma Cells Growth and Metastasis via Sponging MiR-203a
Sign Up to like & getrecommendations! Published in 2018 at "Cellular Physiology and Biochemistry"
DOI: 10.1159/000487178
Abstract: Background/Aims: LncRNA GAS5, a growth suppressor, has been reported to exert anti-tumor actions in various cancers, whereas the exact mechanism underling the anti-tumor action is still unclear. This study was aimed to investigate the effect… read more here.
Keywords: mir 203a; silence; metastasis; growth ... See more keywords
The mechanisms of colorectal cancer cell mesenchymal-epithelial transition induced by hepatocyte exosome-derived miR-203a-3p
Sign Up to like & getrecommendations! Published in 2021 at "BMC Cancer"
DOI: 10.1186/s12885-021-08419-x
Abstract: Background Liver metastasis is the most common cause of death in patients with colorectal cancer (CRC). Phosphatase of regenerating liver-3 induces CRC metastasis by epithelial-to-mesenchymal transition, which promotes CRC cell liver metastasis. Mesenchymal-to-epithelial transition (MET),… read more here.
Keywords: epithelial transition; mir 203a; colorectal cancer; mesenchymal epithelial ... See more keywords
Identification of miR-203a, mir-10a, and miR-194 as predictors for risk of lymphovascular invasion in head and neck cancers
Sign Up to like & getrecommendations! Published in 2021 at "Oncotarget"
DOI: 10.18632/oncotarget.28022
Abstract: Lymphovascular invasion (LVI) is an important prognostic indicator of lymph node metastasis and disease aggressiveness but clear molecular mechanisms mediating this in head and neck cancers (HNSC) remain undefined. To identify important microRNAs (miRNAs) in… read more here.
Keywords: lymphovascular invasion; mir 203a; neck cancers; mir ... See more keywords