The long non‐coding RNA LOC285758 promotes invasion of acute myeloid leukemia cells by down‐regulating miR‐204‐5p
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DOI: 10.1002/2211-5463.12814
Abstract: Acute myeloid leukemia (AML) is the second most common type of leukemia worldwide. It was previously reported that expression of the long noncoding RNA LOC285758 is positively associated with AML cell proliferation, but the underlying… read more here.
Keywords: loc285758; myeloid leukemia; rna loc285758; acute myeloid ... See more keywords
MicroRNA‐204‐5p Deficiency within the vmPFC Region Contributes to Neuroinflammation and Behavioral Disorders via the JAK2/STAT3 Signaling Pathway in Rats
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DOI: 10.1002/advs.202403080
Abstract: Major depressive disorder (MDD) is usually considered associate with immune inflammation and synaptic injury within specific brain regions. However, the molecular mechanisms underlying the neural deterioration resulting in depression remain unclear. Here, it is found… read more here.
Keywords: jak2 stat3; stat3 signaling; jak2; mir 204 ... See more keywords
Long non‐coding RNA PCAT6 targets miR‐204 to modulate the chemoresistance of colorectal cancer cells to 5‐fluorouracil‐based treatment through HMGA2 signaling
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DOI: 10.1002/cam4.1809
Abstract: Colorectal cancer (CRC) is still the third most common cancer in the world with a limited prognosis due to the chemoresistance of CRC cells to 5‐fluorouracil (5‐FU)‐based chemotherapy. In our previous study, we revealed that… read more here.
Keywords: chemoresistance; colorectal cancer; hmga2; crc ... See more keywords
MicroRNA‐204‐5p: A pivotal tumor suppressor
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DOI: 10.1002/cam4.5077
Abstract: MicroRNAs (miRNAs) are a class of non‐coding single‐stranded RNA molecules with a length of approximately 18‐25 nt nucleotides that regulate gene expression post‐transcriptionally. MiR‐204‐5p originates from the sixth intron of the transient receptor potential cation channel… read more here.
Keywords: tumor suppressor; microrna 204; mir 204; tumor ... See more keywords
Silencing of MEG3 inhibited ox‐LDL‐induced inflammation and apoptosis in macrophages via modulation of the MEG3/miR‐204/CDKN2A regulatory axis
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DOI: 10.1002/cbin.11105
Abstract: Atherosclerosis (AS) is one of the most common chronic inflammatory diseases and a major cause of morbidity and mortality. However, the underlying molecular mechanisms of the progression of AS are still largely unknown. Increasing evidence… read more here.
Keywords: meg3; cells treated; cdkn2a; mir 204 ... See more keywords
Silencing of lncRNA UCA1 curbs proliferation and accelerates apoptosis by repressing SIRT1 signals by targeting miR‐204 in pediatric AML
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DOI: 10.1002/jbt.22435
Abstract: The long noncoding RNA urothelial carcinoma‐associated 1 (UCA1) has been reported to sustain the proliferation of acute myeloid leukemia (AML) cells through downregulating cell cycle regulators p27kip1. Yet, the foundational mechanism of UCA1 in AML… read more here.
Keywords: mir 204; pediatric aml; expression; proliferation ... See more keywords
M2 Macrophage‐Extracellular Vesicle‐Derived lncRNA‐NEAT1 Regulates miR‐204‐5p/RRS1‐mediated Cell Cycle to Promote the Occurrence and Development of Colorectal Cancer
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DOI: 10.1002/jbt.70168
Abstract: Colorectal cancer (CRC) is a prevalent malignancy of the digestive system. Here, we explored the role of M2 macrophage‐derived extracellular vesicles (EVs) carrying long non‐coding RNA‐nuclear paraspeckle assembly transcript 1 (lncRNA‐NEAT1) in promoting CRC progression… read more here.
Keywords: lncrna neat1; cell cycle; rrs1; macrophage ... See more keywords
ssc‐miR‐204 regulates porcine preadipocyte differentiation and apoptosis by targeting TGFBR1 and TGFBR2
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DOI: 10.1002/jcb.29306
Abstract: MicroRNAs (miRNAs) take part in a variety of biological processes by regulating target genes. Transforming growth factor β receptor 1 (TGFBR1) and TGFBR2 are crucial members of the TGF‐β family and are serine/threonine kinase receptors.… read more here.
Keywords: differentiation apoptosis; tgfbr1 tgfbr2; preadipocyte differentiation; porcine preadipocyte ... See more keywords
Long noncoding RNA KCNQ1OT1 promotes proliferation, migration, and invasion in maxillary sinus squamous cell carcinoma by regulating miR‐204/EphA7 axis
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DOI: 10.1002/jcb.29548
Abstract: Long noncoding RNAs have been demonstrated to contribute to the development and progression of various cancers. However, the underlying regulatory mechanisms of KCNQ1OT1 in tumorigenesis of maxillary sinus squamous cell carcinoma (MSSCC) remain unknown. Herein,… read more here.
Keywords: maxillary sinus; long noncoding; sinus squamous; kcnq1ot1 ... See more keywords
Linc‐ROR regulates apoptosis in esophageal squamous cell carcinoma via modulation of p53 ubiquitination by targeting miR‐204‐5p/MDM2
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DOI: 10.1002/jcp.29139
Abstract: The long intergenic noncoding RNA, regulator of reprogramming (linc‐ROR) has been reported to participate in tumorigenesis, while its functions and fundamental mechanisms in esophageal squamous cell carcinoma (ESCC) remain unclear. In this study, gain‐of‐function assays… read more here.
Keywords: esophageal squamous; ror; linc ror; 204 mdm2 ... See more keywords
Upregulation of miR‐200a and miR‐204 in MPP+‐treated differentiated PC12 cells as a model of Parkinson’s disease
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DOI: 10.1002/mgg3.548
Abstract: Parkinson's disease (PD) is ranked as the second most common neurodegenerative disorder caused by loss of dopaminergic neurons in the substantia nigra. Micro(mi)RNAs are a class of small noncoding RNAs that regulate gene expression and… read more here.
Keywords: 200a mir; upregulation mir; disease; parkinson disease ... See more keywords