MiR-208a aggravates H2O2-induced cardiomyocyte injury by targeting APC.
Sign Up to like & getrecommendations! Published in 2019 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2019.172668
Abstract: Oxidative stress injury, inducing cardiomyocyte injury, is the major denominator of many cardiovascular diseases. In present study, we aimed to explore the molecular mechanism of microRNA-208a (miR-208a) in oxidative stress-induced cardiomyocyte injury. In this study,… read more here.
Keywords: mir 208a; apc; cardiomyocyte injury; h2o2 induced ... See more keywords
The diagnostic values of circulating miRNAs for hypertension and bioinformatics analysis
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DOI: 10.1042/bsr20180525
Abstract: Few studies have compared the performances of those reported miRNAs as biomarkers for hypertension in a same cohort, we aimed to comprehensively examine the performances of those reported miRNAs as biomarkers for hypertension and identify… read more here.
Keywords: mir 208a; mir 199a; mir; analysis ... See more keywords
MiR-208a-3p functions as an oncogene in colorectal cancer by targeting PDCD4
Sign Up to like & getrecommendations! Published in 2019 at "Bioscience Reports"
DOI: 10.1042/bsr20181598
Abstract: Accumulating evidences have shown microRNAs (miRNAs) play important roles in the progression of human cancers including colorectal cancer (CRC). However, the biological function and molecular mechanism of miRNAs in CRC still remains to be further… read more here.
Keywords: targeting pdcd4; mir 208a; mir; crc ... See more keywords
circRAD18 sponges miR-208a/3164 to promote triple-negative breast cancer progression through regulating IGF1 and FGF2 expression.
Sign Up to like & getrecommendations! Published in 2019 at "Carcinogenesis"
DOI: 10.1093/carcin/bgz071
Abstract: As a new rising star of non-coding RNA, circular RNAs (circRNAs) emerged as vital regulators with biological functions in diverse of cancers. However, the function and precise mechanism of the vast majority of circRNAs in… read more here.
Keywords: mir 208a; igf1 fgf2; circrad18; expression ... See more keywords
The Calcilytic Drug Calhex-231 Ameliorates Vascular Hyporesponsiveness in Traumatic Hemorrhagic Shock by Inhibiting Oxidative Stress and miR-208a-Mediated Mitochondrial Fission
Sign Up to like & getrecommendations! Published in 2020 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2020/4132785
Abstract: Background The calcium-sensing receptor (CaSR) plays a fundamental role in extracellular calcium homeostasis in humans. Surprisingly, CaSR is also expressed in nonhomeostatic tissues and is involved in regulating diverse cellular functions. The objective of this… read more here.
Keywords: calhex 231; mir 208a; fission; traumatic hemorrhagic ... See more keywords
miR-208a in Cardiac Hypertrophy and Remodeling
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DOI: 10.3389/fcvm.2021.773314
Abstract: Various stresses, including pressure overload and myocardial stretch, can trigger cardiac remodeling and result in heart diseases. The disorders are associated with high risk of morbidity and mortality and are among the major health problems… read more here.
Keywords: hypertrophy remodeling; heart; mir 208a; 208a cardiac ... See more keywords
MicroRNA-208a directly targets Src kinase signaling inhibitor 1 to facilitate cell proliferation and invasion in non-small cell lung cancer
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Medicine Reports"
DOI: 10.3892/mmr.2019.10542
Abstract: The abnormal expression of microRNAs (miRNAs/miRs) has a critical function in the formation and progression of non-small cell lung cancer (NSCLC). Therefore, understanding the association between NSCLC and dysregulated miRNAs may allow for the identification… read more here.
Keywords: mir 208a; expression; non small; cancer ... See more keywords