Articles with "mir 216" as a keyword



SNHG16/miR-216-5p/ZEB1 signal pathway contributes to the tumorigenesis of cervical cancer cells.

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Published in 2018 at "Archives of biochemistry and biophysics"

DOI: 10.1016/j.abb.2017.11.003

Abstract: Long non-coding RNAs (lncRNAs) have been confirmed as crucial regulators in tumorgenesis. Small nucleolar RNA host gene 16 (SNHG16) has been recently uncovered to be a potential oncogene in several types of cancers. However, its… read more here.

Keywords: snhg16 mir; 216 zeb1; mir 216; cervical cancer ... See more keywords

Metformin exhibits its therapeutic effect in the treatment of pre-eclampsia via modulating the Met/H19/miR-148a-5p/P28 and Met/H19/miR-216-3p/EBI3 signaling pathways.

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Published in 2019 at "International immunopharmacology"

DOI: 10.1016/j.intimp.2019.105693

Abstract: Metformin (Met) has been found to modify the methylation of H19 and to alter its expression. In addition, IL-27, one of the downstream factors in the H19 signaling pathway, plays an important role in the… read more here.

Keywords: met h19; mir 148a; mir; h19 mir ... See more keywords

Overexpression of miRNA-216 in exosomes derived from umbilical cord mesenchymal stem cells promotes angiogenesis and improves functional recovery after spinal cord injury

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Published in 2025 at "Iranian Journal of Basic Medical Sciences"

DOI: 10.22038/ijbms.2025.85963.18571

Abstract: Objective(s): This study aimed to engineer miR-216-overexpressing umbilical cord mesenchymal stem cells (UCMSCs) to generate miR-216-enriched UCMSC-derived exosomes (UCMSC-Exos) and evaluate their therapeutic potential in Spinal cord injury (SCI). Materials and Methods: miR-216 overexpression was… read more here.

Keywords: cord; ucmsc exos; ucmsc mir; mir 216oe ... See more keywords

Isoflurane Suppresses Proliferation, Migration, and Invasion and Facilitates Apoptosis in Colorectal Cancer Cells Through Targeting miR-216

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Published in 2021 at "Frontiers in Medicine"

DOI: 10.3389/fmed.2021.658926

Abstract: Objective: Surgery is the first line treatment of colorectal cancer (CRC). Anesthetic isoflurane may improve outcomes of cancer surgery. Herein, we investigated the effects of isoflurane on malignant behaviors of CRC cells and its underlying… read more here.

Keywords: proliferation migration; sw620 hct116; cancer; isoflurane ... See more keywords