MiR‐216b inhibits osteosarcoma cell proliferation, migration, and invasion by targeting Forkhead Box M1
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.27822
Abstract: Osteosarcoma (OS) is considered the most common type of primary malignant bone tumor, which has a high rate of mortality in children and adolescents. However, the current treatment methods for OS are ineffective. Therefore, there… read more here.
Keywords: 216b foxm1; mir 216b; forkhead box; invasion ... See more keywords
Overexpression of miR‐216b: Prognostic and predictive value in acute myeloid leukemia
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.26171
Abstract: Accumulating studies have shown that miR‐216b acted as a tumor suppressor and was down‐regulated in solid tumors. However, little studies revealed the role or clinical implication of miR‐216b in blood cancers. Herein, we reported miR‐216b… read more here.
Keywords: overexpression; mir 216b; 216b expression; expression ... See more keywords
LncRNA KCNQ1OT1 acts as miR-216b-5p sponge to promote colorectal cancer progression via up-regulating ZNF146
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Molecular Histology"
DOI: 10.1007/s10735-020-09942-0
Abstract: Long non-coding RNAs (lncRNAs) have shown to act as important regulators in cancer biology. The aim of this study was to investigate the role and mechanism of lncRNA KCNQ1 opposite strand/antisense transcript 1 (KCNQ1OT1) in… read more here.
Keywords: crc cells; mir 216b; znf146; kcnq1ot1 ... See more keywords
LncRNA MYCNOS promotes glioblastoma cell proliferation by regulating miR-216b/FOXM1 axis.
Sign Up to like & getrecommendations! Published in 2021 at "Metabolic brain disease"
DOI: 10.1007/s11011-021-00729-0
Abstract: MYCNOS is an oncogenic lncRNA in liver cancer, but its role in glioblastoma (GBM) is unknown. We predicted that MYCNOS might interact with miR-216b, which targets FOXM1 to perform tumor suppressive roles. This study was… read more here.
Keywords: 216b foxm1; overexpression; mir 216b; cell proliferation ... See more keywords
miR-216b suppresses breast cancer growth and metastasis by targeting SDCBP.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2016.10.003
Abstract: Breast cancer is the most deadly cancer among women and the second leading cause of cancer death worldwide. Treatment effectiveness is complicated with tumor invasiveness/drug resistance. To tailor treatments more effectively to individual patients, it… read more here.
Keywords: sdcbp; mir 216b; breast cancer; cancer ... See more keywords
miR-216b enhances the efficacy of vemurafenib by targeting Beclin-1, UVRAG and ATG5 in melanoma.
Sign Up to like & getrecommendations! Published in 2018 at "Cellular signalling"
DOI: 10.1016/j.cellsig.2017.09.024
Abstract: Autophagy maintains cells survival in many stressful conditions including starvation, growth factor deprivation and misfolded protein accumulation. Additionally, autophagic survival mechanisms are used by transformed tumor cells to inhibit cell death, limit drug effectiveness and… read more here.
Keywords: melanoma; mir 216b; drug; uvrag atg5 ... See more keywords
WITHDRAWN: MiR-216b-5p attenuates chronic constriction injury-induced neuropathic pain in female rats by targeting MAL2 and inactivating Wnt/β-catenin signaling pathway
Sign Up to like & getrecommendations! Published in 2020 at "Neurochemistry international"
DOI: 10.1016/j.neuint.2020.104930
Abstract: MicroRNAs (miRNAs) are crucial regulators of neuronal functions and participate in the development of neuropathic pain. MiR-216b-5p has been reported to be involved in the progression of many human diseases. However, the biological effect and… read more here.
Keywords: mir 216b; catenin signaling; signaling pathway; neuropathic pain ... See more keywords
Knockout of Acinar Enriched microRNAs in Mice Promote Duct Formation But Not Pancreatic Cancer
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DOI: 10.1038/s41598-019-47566-x
Abstract: The pancreatic acinar-enriched miR-216a, miR-216b and miR-217 are encoded within the miR217HG. These miRNAs have been purported to play a tumor suppressive role as their expression is reduced in both human and mouse pancreatic ductal… read more here.
Keywords: mir 216b; mir 216a; mir; mice ... See more keywords
LncRNA-SNHG1 promotes paclitaxel resistance of gastric cancer cells through modulating the miR-216b-5p-hexokianse 2 axis.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of chemotherapy"
DOI: 10.1080/1120009x.2022.2157618
Abstract: Gastric cancer (GC) is one of the most malignant tumors with high incidence and poor prognosis. Currently, the combination of surgery with chemo- or radiotherapy is widely applied therapeutic strategy against GC. However, development of… read more here.
Keywords: snhg1; resistance; mir 216b; gastric cancer ... See more keywords
MicroRNA-216b regulates cell proliferation, invasion and cycle progression via interaction with cyclin T2 in gastric cancer
Sign Up to like & getrecommendations! Published in 2020 at "Anti-Cancer Drugs"
DOI: 10.1097/cad.0000000000000915
Abstract: Gastric cancer has become the second most common malignant tumor in the world, revealing the molecular mechanism of gastric cancer development is essential for the treatment of gastric cancer and improvement of prognosis. Recent studies… read more here.
Keywords: gastric cancer; mir 216b; cancer; proliferation invasion ... See more keywords
lncRNA DSCAM-AS1 downregulates miR-216b to promote the migration and invasion of colorectal adenocarcinoma cells
Sign Up to like & getrecommendations! Published in 2019 at "OncoTargets and therapy"
DOI: 10.2147/ott.s213301
Abstract: Background It has been reported that lncRNA DSCAM-AS1 plays an oncogenic role in breast cancer. In the present study we explored the role of DSCAM-AS1 in colorectal adenocarcinoma (CRA). Methods: Gene expression was analyzed by… read more here.
Keywords: migration invasion; dscam as1; mir 216b; tumor ... See more keywords