Bladder cancer tissue‐derived exosomes suppress ferroptosis of T24 bladder cancer cells by transporting miR‐217
Sign Up to like & getrecommendations! Published in 2022 at "Environmental and Molecular Mutagenesis"
DOI: 10.1002/em.22520
Abstract: It has been reported that miR‐217 can inhibit the oncogenic activity and progression of bladder cancer (BCa) cells, but it has not been explored whether miR‐217 is involved in the regulation of ferroptosis. In the… read more here.
Keywords: bladder cancer; bladder; mir 217; ferroptosis ... See more keywords
Regulation of endothelial cell senescence via the miR-217/FOXO3 axis
Sign Up to like & getrecommendations! Published in 2025 at "Biogerontology"
DOI: 10.1007/s10522-025-10290-3
Abstract: The accumulation of senescent endothelial cells within the endothelium leads to vascular dysfunction. Independent studies have linked miR-217, a senescence-associated microRNA and FOXO3, a longevity factor, to cellular senescence in different study models. However, their… read more here.
Keywords: senescence; foxo3 axis; mir 217; huvecs ... See more keywords
Down–regulating miR-217-5p Protects Cardiomyocytes against Ischemia/Reperfusion Injury by Restoring Mitochondrial Function via Targeting SIRT1
Sign Up to like & getrecommendations! Published in 2020 at "Inflammation"
DOI: 10.1007/s10753-020-01343-5
Abstract: Downregulating miR-217-5p could protect cardiomyocytes against ischemia/reperfusion (I/R) injury, but its role in restoring mitochondrial function of I/R-injured cardiomyocytes remained unclear. H9C2 cardiomyocyte-derived cell line with I/R injury was established in vitro on the basis… read more here.
Keywords: reperfusion; mitochondrial function; injury; mir 217 ... See more keywords
LncRNA-NEAT1 blocks the Wnt/β-catenin signaling pathway by targeting miR-217 to inhibit trophoblast cell migration and invasion
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Assisted Reproduction and Genetics"
DOI: 10.1007/s10815-024-03124-7
Abstract: This study aimed to study the correlation between preeclampsia (PE) and lncRNA nuclear paraspeckle assembly transcript 1 (NEAT1), and to examine the molecular mechanisms behind the development of PE. 30 PE and 30 normal pregnant… read more here.
Keywords: migration; mir 217; cell; trophoblast ... See more keywords
Baicalin augments the differentiation of osteoblasts via enhancement of microRNA-217
Sign Up to like & getrecommendations! Published in 2019 at "Molecular and Cellular Biochemistry"
DOI: 10.1007/s11010-019-03632-6
Abstract: Baicalin (BAI), a sort of flavonoid monomer, acquires from Scutellaria baicalensis Georgi, which was forcefully reported in diversified ailments due to the pleiotropic properties. But, the functions of BAI in osteoblast differentiation have not been addressed.… read more here.
Keywords: differentiation osteoblasts; differentiation; bai; mc3t3 cells ... See more keywords
Inhibition of miR-217 Protects Against Myocardial Ischemia–Reperfusion Injury Through Inactivating NF-κB and MAPK Pathways
Sign Up to like & getrecommendations! Published in 2020 at "Cardiovascular Engineering and Technology"
DOI: 10.1007/s13239-019-00452-z
Abstract: Purpose Recent studies have demonstrated that miRNAs play a vital role in regulating myocardial ischemia/reperfusion injury (MIRI). MiR-217 has been proven to be implicated in cardiac diseases such as chronic heart failure and cardiac myxoma.… read more here.
Keywords: inactivating mapk; inhibition; myocardial ischemia; mapk pathways ... See more keywords
Repression of miR-217 protects against high glucose-induced podocyte injury and insulin resistance by restoring PTEN-mediated autophagy pathway.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2016.12.145
Abstract: Podocyte damage is the initial hallmark of diabetic nephropathy (DN), leading to the increasing morbidity and mortality in diabetic patients. Recent researches have corroborated the critical roles of miRNAs in the pathological progression of DN.… read more here.
Keywords: insulin; injury insulin; insulin resistance; autophagy pathway ... See more keywords
miR-217 suppresses proliferation and promotes apoptosis in cardiac myxoma by targeting Interleukin-6.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.06.106
Abstract: Cardiac myxoma (CM) is a prevalent primary cardiac tumor. miR-217 plays a vital role in tumorigenesis of various cancers, however, its role and underlying molecular mechanism in human CM remain poorly understood. Here, we reported… read more here.
Keywords: cardiac myxoma; mir; proliferation; 217 suppresses ... See more keywords
Chemerin-induced angiogenesis and adipogenesis in 3 T3-L1 preadipocytes is mediated by lncRNA Meg3 through regulating Dickkopf-3 by sponging miR-217.
Sign Up to like & getrecommendations! Published in 2019 at "Toxicology and applied pharmacology"
DOI: 10.1016/j.taap.2019.114815
Abstract: PURPOSE Obesity is often caused by the excess adipogenesis and regulated by long non-coding RNAs (lncRNAs) and microRNAs (miRNAs). We performed this study to investigate the influence of Meg3 expression on adipogenesis and also the… read more here.
Keywords: meg3; adipogenesis; expression; mir 217 ... See more keywords
Small extracellular vesicles deliver miR-21 and miR-217 as pro-senescence effectors to endothelial cells
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Extracellular Vesicles"
DOI: 10.1080/20013078.2020.1725285
Abstract: ABSTRACT The role of epigenetics in endothelial cell senescence is a cutting-edge topic in ageing research. However, little is known of the relative contribution to pro-senescence signal propagation provided by microRNAs shuttled by extracellular vesicles… read more here.
Keywords: extracellular vesicles; mir mir; senescence; pro senescence ... See more keywords
circBIRC6 contributes to the development of non-small cell lung cancer via regulating microRNA-217/amyloid beta precursor protein binding protein 2 axis
Sign Up to like & getrecommendations! Published in 2022 at "Chinese Medical Journal"
DOI: 10.1097/cm9.0000000000001940
Abstract: Abstract Background: Circular RNAs (circRNAs) are considered to be important regulators in cancer biology. In this study, we focused on the effect of circRNA baculoviral inhibitor of apoptosis protein (IAP) repeat containing 6 (circBIRC6) on… read more here.
Keywords: cell; mir 217; circbirc6; formation ... See more keywords