miR‐219a‐5p Regulates Rorβ During Osteoblast Differentiation and in Age‐related Bone Loss
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.3586
Abstract: Developing novel approaches to treat skeletal disorders requires an understanding of how critical molecular factors regulate osteoblast differentiation and bone remodeling. We have reported that (1) retinoic acid receptor‐related orphan receptor beta (Rorβ) is upregulated… read more here.
Keywords: ror expression; mir 219a; ror; bone ... See more keywords
miR‐219a‐5p inhibits the pyroptosis in knee osteoarthritis by inactivating the NLRP3 signaling via targeting FBXO3
Sign Up to like & getrecommendations! Published in 2022 at "Environmental Toxicology"
DOI: 10.1002/tox.23627
Abstract: This work was to identify the function and mechanism of miR‐219a‐5p in regulating knee osteoarthritis (KOA). read more here.
Keywords: knee osteoarthritis; mir 219a; 219a inhibits; inhibits pyroptosis ... See more keywords
miR-219a-5p Ameliorates Hepatic Ischemia/Reperfusion Injury via Impairing TP53BP2
Sign Up to like & getrecommendations! Published in 2019 at "Digestive Diseases and Sciences"
DOI: 10.1007/s10620-019-05535-4
Abstract: BackgroundHepatic ischemia/reperfusion (I/R) injury is a serious complication that occurs upon hypovolemic shock, liver resection, and transplantation. A significant age-dependent difference in the injury response to hepatic I/R in both human and animal models has… read more here.
Keywords: mir 219a; ischemia reperfusion; reperfusion injury; injury ... See more keywords
MicroRNA-219a-5p suppresses intestinal inflammation through inhibiting Th1/Th17-mediated immune responses in inflammatory bowel disease
Sign Up to like & getrecommendations! Published in 2019 at "Mucosal Immunology"
DOI: 10.1038/s41385-019-0216-7
Abstract: MicroRNA (miR)-219a-5p has been implicated in the development of numerous progression of carcinoma and autoimmune diseases. However, whether miR-219a-5p is involved in the pathogenesis of inflammatory bowel disease (IBD) remains elusive. In this study, we… read more here.
Keywords: mir 219a; th1 th17; inflammation; cd4 cells ... See more keywords
miR-219a-5p enhances the radiosensitivity of non-small cell lung cancer cells through targeting CD164
Sign Up to like & getrecommendations! Published in 2020 at "Bioscience Reports"
DOI: 10.1042/bsr20192795
Abstract: Abstract Lung cancer is one of the leading causes of cancer-associated mortality. Non-small cell lung carcinoma (NSCLC) accounts for 70–85% of the total cases of lung cancer. Radioresistance frequently develops in NSCLC in the middle… read more here.
Keywords: expression; lung; regulation; mir 219a ... See more keywords
miR-219a-5p inhibits breast cancer cell migration and epithelial-mesenchymal transition by targeting myocardin-related transcription factor A
Sign Up to like & getrecommendations! Published in 2017 at "Acta Biochimica et Biophysica Sinica"
DOI: 10.1093/abbs/gmx114
Abstract: Although many miRNAs are reported to be involved in tumor formation and progression, the effect of miR-219a-5p on breast cancer metastasis is not well-known. The aim of this study is to investigate the effect of… read more here.
Keywords: mrtf; breast; mir 219a; breast cancer ... See more keywords
Screening the expression of several miRNAs from TaqMan Low Density Array in traumatic brain injury: miR‐219a‐5p regulates neuronal apoptosis by modulating CCNA2 and CACUL1
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Neurochemistry"
DOI: 10.1111/jnc.14717
Abstract: Circulating microRNAs (miRNAs) have emerged as diagnostic and prognostic biomarkers for traumatic brain injury (TBI). However, a comprehensive characterization of the serum miRNA profile in patients with TBI and the roles of these potential markers… read more here.
Keywords: mir 219a; brain injury; mir; traumatic brain ... See more keywords
MicroRNA‐219a‐5p−mediated inhibition of CaMKIIγ facilitates vestibular compensation in acute vertigo by promoting protein kinase C expression
Sign Up to like & getrecommendations! Published in 2020 at "Annals of the New York Academy of Sciences"
DOI: 10.1111/nyas.14376
Abstract: Vestibular compensation (VC) refers to a behavioral recovery process in which firing rates of bilateral vestibular nuclei neurons are rebalanced. Our study aimed to investigate the underlying mechanism by which miR‐219a‐5p regulates Ca2+/calmodulin–dependent protein kinase… read more here.
Keywords: vestibular compensation; mir 219a; acute vertigo; camkii ... See more keywords