Circular RNA circZNF292 regulates H2O2‐induced injury in human lens epithelial HLE‐B3 cells depending on the regulation of the miR‐222‐3p/E2F3 axis
Sign Up to like & getrecommendations! Published in 2021 at "Cell Biology International"
DOI: 10.1002/cbin.11615
Abstract: Circular RNAs (circRNAs) play important roles in the pathogenesis of age‐related cataract (ARC). CircRNA zinc finger protein 292 (circZNF292, hsa_circ_0004058) is downregulated in ARC lens capsules. Here, we focused on its precise roles in oxidative… read more here.
Keywords: mir 222; h2o2 induced; hle cells; cell ... See more keywords
MicroRNA‐222‐3p associated with Helicobacter pylori targets HIPK2 to promote cell proliferation, invasion, and inhibits apoptosis in gastric cancer
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.26542
Abstract: Gastric cancer ranks as the second leading cause of malignancy‐related death worldwide, and always diagnosed at advanced stage. MicroRNA‐222‐3p (miR‐222‐3p) is aberrantly upregulated in various malignant tumors including gastric cancer, but its role and underlying… read more here.
Keywords: mir 222; gastric cancer; cell proliferation; cancer ... See more keywords
The Mechanism of miR-222 Targets Matrix Metalloproteinase 1 in Regulating Fibroblast Proliferation in Hypertrophic Scars
Sign Up to like & getrecommendations! Published in 2021 at "Aesthetic Plastic Surgery"
DOI: 10.1007/s00266-021-02331-2
Abstract: To the Editor, We have read the recent article by Zhang et al. [1] on investigating the value of miR-222 in hypertrophic scars (HS). In this study, the authors concluded that the overexpression of miR-222… read more here.
Keywords: mir 222; hypertrophic scars; fibroblast proliferation; group ... See more keywords
Clinical impact of circulating oncogenic MiRNA-221 and MiRNA-222 in glioblastoma multiform
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Neuro-Oncology"
DOI: 10.1007/s11060-019-03256-2
Abstract: Glioblastoma multiform (GBM); most fatal brain cancer, is incurable with molecular diversity hence identification of molecular targets that contribute to GBM tumorgenesis will be suitable for the development of diagnostic and treatment strategies. Micro-RNAs (miR);… read more here.
Keywords: mir 222; mirna; mir; mir 221 ... See more keywords
Verification of candidate microRNA markers for parathyroid carcinoma
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DOI: 10.1007/s12020-018-1551-2
Abstract: PurposeParathyroid carcinoma (PCa) is a rare endocrine malignancy with poor prognosis and is often difficult to accurately diagnose both before and after surgery. Dysregulated microRNA (miRNA) levels have been identified in PCa using a limited… read more here.
Keywords: mir 139; mir 222; mir 30b; mir ... See more keywords
HMGA1 exacerbates tumor progression by activating miR-222 through PI3K/Akt/MMP-9 signaling pathway in uveal melanoma.
Sign Up to like & getrecommendations! Published in 2019 at "Cellular signalling"
DOI: 10.1016/j.cellsig.2019.109386
Abstract: High-mobility group A1 (HMGA1), an architectural transcription factor, participates in different human tumors' biological progression. HMGA1 overexpression is associated with malignant cellular behavior in a wide range of cancers but the underlying mechanism remains poorly… read more here.
Keywords: hmga1; mir 222; progression; pi3k akt ... See more keywords
MicroRNA miR-222 mediates pioglitazone beneficial effects on skeletal muscle of diet-induced obese mice
Sign Up to like & getrecommendations! Published in 2020 at "Molecular and Cellular Endocrinology"
DOI: 10.1016/j.mce.2019.110661
Abstract: Pioglitazone belongs to the class of drugs thiazolidinediones (TZDs) and is an oral hypoglycemic drug, used in the treatment of type 2 diabetes, which improves insulin sensitivity in target tissues. Adipose tissue is the main… read more here.
Keywords: skeletal muscle; mir 222; obese mice; pioglitazone ... See more keywords
Stepwise detection and evaluation reveal miR-10b and miR-222 as a remarkable prognostic pair for glioblastoma
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DOI: 10.1038/s41388-019-0867-6
Abstract: Despite the existence of many clinical and molecular factors reported that contribute to survival in glioblastoma, prevailing studies fell into partial or local feature selection for survival analysis. We proposed a feature selection strategy including… read more here.
Keywords: mir 222; detection; glioblastoma; mir 10b ... See more keywords
MicroRNA-222 promotes drug resistance to doxorubicin in breast cancer via regulation of miR-222/bim pathway
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DOI: 10.1042/bsr20190650
Abstract: Resistance to doxorubicin (DOX) is the most common clinical problem in breast cancer therapy, and the underlying molecular mechanism remains to be investigated. MicroRNAs (miRNAs) exhibit important regulatory functions in various malignant tumors including breast… read more here.
Keywords: breast cancer; resistance; bim; mir 222 ... See more keywords
MiR-222-3p inhibits formation of medulloblastoma stem-like cells by targeting Notch2/c-myc signaling pathway
Sign Up to like & getrecommendations! Published in 2022 at "Immunopharmacology and Immunotoxicology"
DOI: 10.1080/08923973.2022.2062381
Abstract: Abstract Background Medulloblastoma (MB) is an embryonal tumor of the cerebellum, which commonly occurs in childhood. Herein, we investigated the effects of miR-222-3p on the formation of MB stem-like cells via the Notch2/c-myc pathway. Methods… read more here.
Keywords: notch2 myc; cell; formation; stem ... See more keywords
Tumor-Secreted Exosomal miR-222 Promotes Tumor Progression via Regulating P27 Expression and Re-Localization in Pancreatic Cancer
Sign Up to like & getrecommendations! Published in 2018 at "Cellular Physiology and Biochemistry"
DOI: 10.1159/000495281
Abstract: Background/Aims: MicroRNAs (miRNAs) or exosomes have recently been shown to play vital regulatory or communication roles in cancer biology. However, the roles and mechanisms of exosomal miRNAs in pancreatic ductal adenocarcinoma (PDAC) remain unknown. We… read more here.
Keywords: mir 222; p27 expression; exosomal mir; tumor ... See more keywords