LINC00961 inhibits the migration and invasion of colon cancer cells by sponging miR‐223‐3p and targeting SOX11
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Medicine"
DOI: 10.1002/cam4.2850
Abstract: Long noncoding RNAs play essential roles in colon cancer tumorigenesis. This study aimed to explore the potential function and molecular mechanisms of LINC00961 in colon cancer. qPCR results showed that LINC00961 was downregulated in colon… read more here.
Keywords: linc00961; colon cancer; mir 223; cancer cells ... See more keywords
miR‐223 promotes regenerative myeloid cell phenotype and function in the demyelinated central nervous system
Sign Up to like & getrecommendations! Published in 2019 at "Glia"
DOI: 10.1002/glia.23576
Abstract: In the injured central nervous system, myeloid cells, including macrophages and microglia, are key contributors to both myelin injury and repair. This immense plasticity emphasizes the need to further understand the precise molecular mechanisms that… read more here.
Keywords: phenotype function; nervous system; central nervous; myeloid cell ... See more keywords
miR‐223 improves intestinal inflammation through inhibiting the IL‐6/STAT3 signaling pathway in dextran sodium sulfate‐induced experimental colitis
Sign Up to like & getrecommendations! Published in 2020 at "Immunity"
DOI: 10.1002/iid3.395
Abstract: The pathogenesis of inflammatory bowel disease (IBD) has not yet been clarified and is closely related to several pro‐inflammatory factors. MicroRNA‐233 (miR‐223) might be involved in the development of IBD; however, the mechanism underlying its… read more here.
Keywords: dextran sodium; sodium sulfate; mir 223;
PARP‐1 modulates the expression of miR‐223 through histone acetylation to involve in the hydroquinone‐induced carcinogenesis of TK6 cells
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23142
Abstract: The upstream regulators of microRNAs were rarely reported. Hydroquinone (HQ) is the main metabolite of benzene, one of the important environmental factors contributing to leukemia and lymphoma. In HQ‐induced malignant transformed TK6 (TK6‐HT) cells, the… read more here.
Keywords: expression mir; tk6 cells; hydroquinone; mir 223 ... See more keywords
Knockdown of LncRNA DLX6-AS1 inhibits HK-2 cell pyroptosis via regulating miR-223-3p/NLRP3 pathway in lipopolysaccharide-induced acute kidney injury
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Bioenergetics and Biomembranes"
DOI: 10.1007/s10863-020-09845-5
Abstract: Sepsis-induced acute kidney injury (AKI) represents a severe medical complication. Recently, there is growing evidence indicating the regulatory role of long non-coding RNAs (lncRNAs) in AKI pathophysiology. The present study investigated lncRNA DLX6 antisense RNA… read more here.
Keywords: pyroptosis; dlx6; aki; expression ... See more keywords
MiR-223-3p levels in the plasma and atherosclerotic plaques are increased in aged patients with carotid artery stenosis; association with HDL-related proteins.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular biology reports"
DOI: 10.1007/s11033-021-06636-y
Abstract: BACKGROUND Cardiovascular diseases are still the main cause of death worldwide. Our aim was to analyse the link between miR-223-3p levels, dysfunctional HDL and the age of patients with carotid artery stenosis (CAS). METHODS AND… read more here.
Keywords: carotid artery; related proteins; 223 levels; mir 223 ... See more keywords
miR-223/Hsp70/JNK/JUN/miR-223 feedback loop modulates the chemoresistance of osteosarcoma to cisplatin.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.02.091
Abstract: Osteosarcoma (OS) is a primary bone malignancy with a five-year survival rate of 60%; the chemoresistance of OS still remains a huge challenge. Heat shock protein 70 (Hsp70), a member of HSP family, is overexpressed… read more here.
Keywords: jnk jun; hsp70; mir 223; chemoresistance ... See more keywords
Correlation between miR-223 and IL-35 and their regulatory effect in children with allergic rhinitis.
Sign Up to like & getrecommendations! Published in 2020 at "Clinical immunology"
DOI: 10.1016/j.clim.2020.108383
Abstract: The relationship between microRNA (miR) and immune activity in allergic rhinitis (AR) remains unclear. 37 children with AR and 30 healthy children were enrolled to study the correlation of miR-223 and IL-35. There was a… read more here.
Keywords: correlation; mir 223; allergic rhinitis; correlation mir ... See more keywords
Paeonol inhibits NLRP3 mediated inflammation in rat endothelial cells by elevating hyperlipidemic rats plasma exosomal miRNA-223.
Sign Up to like & getrecommendations! Published in 2020 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2020.173473
Abstract: Atherosclerosis (AS) is a multifactorial chronic inflammatory disease, and hyperlipidemia is the important factors leading to AS, which can cause vascular endothelial dysfunction. Paeonol (Pae) is a potential therapeutic drug for AS, and we have… read more here.
Keywords: elevating hyperlipidemic; rats plasma; mediated inflammation; hyperlipidemic rats ... See more keywords
Long non‐coding RNA activated by transforming growth factor beta alleviates lipopolysaccharide‐induced inflammatory injury via regulating microRNA‐223 in ATDC5 cells
Sign Up to like & getrecommendations! Published in 2019 at "International Immunopharmacology"
DOI: 10.1016/j.intimp.2019.01.056
Abstract: &NA; Osteoarthritis (OA) is a conversant joint disease, which seriously threatens the health of the elderly, and even leads to disability. Long non‐coding RNA‐activated by transforming growth factor beta (lncRNA‐ATB) has been reported in diverse… read more here.
Keywords: lncrna atb; inflammatory injury; atdc5 cells; mir 223 ... See more keywords
MicroRNA-223 modulates the IL-4-medicated macrophage M2-type polarization to control the progress of sepsis.
Sign Up to like & getrecommendations! Published in 2021 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2021.107783
Abstract: MicroRNAs play a variety of roles in the progress of inflammation. Herein, we investigated the roles of miR-223 in governing macrophage polarization balance in the progress of sepsis. We firstly observed that miR-223 was down-regulated… read more here.
Keywords: progress sepsis; mir 223; type polarization; polarization ... See more keywords