Articles with "mir 224" as a keyword



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MicroRNA‐224 inhibition prevents progression of cervical carcinoma by targeting PTX3

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Published in 2018 at "Journal of Cellular Biochemistry"

DOI: 10.1002/jcb.27370

Abstract: Cervical carcinoma is known as one of the most lethal and common conditions in women worldwide. Increasing evidence shows that microRNAs (miRs) may be involved in the pathogenesis of cervical carcinoma. This study investigates the… read more here.

Keywords: mir 224; progression cervical; cervical carcinoma; ptx3 ... See more keywords
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miR‐224‐5p inhibits proliferation, migration, and invasion by targeting PIK3R3/AKT3 in uveal melanoma

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Published in 2019 at "Journal of Cellular Biochemistry"

DOI: 10.1002/jcb.28507

Abstract: Uveal melanoma (UM) is the most common primary intraocular malignancy in adults. Accumulating investigations have identified the aberrant expression of miRNAs (microRNAs) in UM, such as miR‐181, miR‐20a, miR‐144, miR‐146a. The purpose of this study… read more here.

Keywords: mir 224; proliferation; expression; pik3r3 akt3 ... See more keywords
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MicroRNA‐224 suppresses osteoblast differentiation by inhibiting SMAD4

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Published in 2018 at "Journal of Cellular Physiology"

DOI: 10.1002/jcp.26596

Abstract: Osteoblast differentiation was found to be regulated by a variety of cell signaling and intracellular regulatory factors. In this study, we aimed at investigating the regulatory effect of microRNA‐224 on osteoblast differentiation and its molecular… read more here.

Keywords: mir 224; microrna 224; differentiation; osteoblast differentiation ... See more keywords
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MiR‐193a‐3p and miR‐224 mediate renal cell carcinoma progression by targeting alpha‐2,3‐sialyltransferase IV and the phosphatidylinositol 3 kinase/Akt pathway

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Published in 2018 at "Molecular Carcinogenesis"

DOI: 10.1002/mc.22826

Abstract: Tumor metastasis is a major cause of cancer‐related death in renal cell carcinoma (RCC). MicroRNAs (miRNAs) have been widely known to modulate proliferation invasion, metastasis, and apoptosis of cancer cells. In this study, we aimed… read more here.

Keywords: 193a mir; mir 224; mir; rcc ... See more keywords
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Engineering Bioactive M2 Macrophage-Polarized, Anti-inflammatory, miRNA-Based Liposomes for Functional Muscle Repair: From Exosomal Mechanisms to Biomaterials.

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Published in 2022 at "Small"

DOI: 10.1002/smll.202201957

Abstract: Severe inflammation and myogenic differentiation disorder are the major obstacles to skeletal muscle healing after injury. MicroRNAs (miRNAs) play an important role as regulatory molecules during the process of muscle healing, but the detailed mechanism… read more here.

Keywords: inflammatory mirna; mir 224; muscle; anti inflammatory ... See more keywords
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The Long Non-coding RNA NEAT1/miR-224-5p/IL-33 Axis Modulates Macrophage M2a Polarization and A1 Astrocyte Activation.

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Published in 2021 at "Molecular neurobiology"

DOI: 10.1007/s12035-021-02405-x

Abstract: To identify potential regulators and investigate the molecular mechanism of macrophage polarization affecting astrocyte activation from the perspective of non-coding RNA regulation, we isolated mouse bone marrow mononuclear cells (BMMNCs)-induced macrophages toward M1 or M2a… read more here.

Keywords: astrocyte activation; mir 224; activation; neat1 knockdown ... See more keywords
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LncRNA LINC01094 contributes to glioma progression by modulating miR-224-5p/CHSY1 axis.

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Published in 2021 at "Human cell"

DOI: 10.1007/s13577-021-00637-6

Abstract: Glioma serves as the most common malignancy influencing modern people and is associated with severe morbidity and high mortality. Long non-coding RNAs (lncRNAs) as crucial regulators participate in multiple cancer progression. However, the role of… read more here.

Keywords: glioma; mir 224; lncrna linc01094; glioma progression ... See more keywords
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LINC00619 restricts gastric cancer progression by preventing microRNA-224-5p-mediated inhibition of OPCML.

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Published in 2020 at "Archives of biochemistry and biophysics"

DOI: 10.1016/j.abb.2020.108390

Abstract: Several long intergenic noncoding RNAs (lincRNAs) have been linked to carcinogenesis; however, little is known about the role of LINC00619 in gastric cancer (GC). LINC00619 was identified among differentially expressed lncRNAs linked to gastric cancer… read more here.

Keywords: 224 mediated; gastric cancer; mir 224; linc00619 ... See more keywords
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Well-Ordered Au Nanoarray for Sensitive and Reproducible Detection of Hepatocellular Carcinoma-Associated miRNA via CHA-Assisted SERS/Fluorescence Dual-Mode Sensing.

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Published in 2023 at "Analytical chemistry"

DOI: 10.1021/acs.analchem.2c05640

Abstract: Ultra-sensitive detection of cancer-related biomarkers in serum is of great significance for early diagnosis, treatment, prognosis, and staging of cancer. In this work, we proposed a surface-enhanced Raman scattering and fluorescence (SERS/FL) dual-mode biosensor for… read more here.

Keywords: hepatocellular carcinoma; mir 224; detection; dual mode ... See more keywords
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Downregulated USP3 mRNA functions as a competitive endogenous RNA of SMAD4 by sponging miR-224 and promotes metastasis in colorectal cancer

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Published in 2017 at "Scientific Reports"

DOI: 10.1038/s41598-017-04368-3

Abstract: Increasing evidence shows that competitive endogenous RNAs (ceRNAs) can affect the expression of other transcripts by sequestering common microRNAs (miRNAs), and participate in tumourigenesis. As a potent tumour suppressor in colorectal cancer (CRC), SMAD4 is… read more here.

Keywords: smad4; mir 224; colorectal cancer; competitive endogenous ... See more keywords
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MicroRNA-224 down-regulates Glycine N-methyltransferase gene expression in Hepatocellular Carcinoma

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Published in 2018 at "Scientific Reports"

DOI: 10.1038/s41598-018-30682-5

Abstract: Glycine N-methyltransferase (GNMT) is a tumor suppressor for HCC. It is down-regulated in HCC, but the mechanism is not fully understood. MicroRNA-224 (miR-224) acts as an onco-miR in HCC. This study is the first to… read more here.

Keywords: mir 224; microrna 224; expression; gnmt ... See more keywords