Downregulation of microRNA‐23b protects against ischemia‐reperfusion injury via p53 signaling pathway by upregulating MDM4 in rats
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.27748
Abstract: Total knee arthroplasty is a commonly performed safe procedure and typically executed in severe knee arthritis, but it also triggers ischemia‐reperfusion injury (IRI). More recently, microRNAs (miRs) have been reported to play a contributory role… read more here.
Keywords: p53 signaling; mdm4; mir 23b; signaling pathway ... See more keywords
Involvement of microRNA-23b in TNF-α-reduced BMSC osteogenic differentiation via targeting runx2
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Bone and Mineral Metabolism"
DOI: 10.1007/s00774-017-0886-8
Abstract: Elucidation of the molecular mechanism governing bone marrow mesenchymal stem cell (BMSC) osteogenic differentiation is of great importance for improving the treatment of osteoporosis. TNF-α is a well-known inhibitory factor during osteogenic differentiation of BMSCs.… read more here.
Keywords: runx2; tnf; bmsc osteogenic; mir 23b ... See more keywords
KCNQ1OT1 inhibition alleviates high glucose-induced podocyte injury by adsorbing miR-23b-3p and regulating Sema3A
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and Experimental Nephrology"
DOI: 10.1007/s10157-021-02173-x
Abstract: Diabetic nephropathy (DN), a diabetic complication, is the leading cause of end-stage renal disease. KCNQ1 opposite strand/antisense transcript 1 (KCNQ1OT1), a long non-coding RNA, has been unmasked to participate in the pathogenesis of DN. However,… read more here.
Keywords: apoptosis; mir 23b; proliferation; high glucose ... See more keywords
Attenuation of Sepsis-Induced Cardiomyopathy by Regulation of MicroRNA-23b Is Mediated Through Targeting of MyD88-Mediated NF-κB Activation
Sign Up to like & getrecommendations! Published in 2019 at "Inflammation"
DOI: 10.1007/s10753-019-00958-7
Abstract: Myocardial cell injury or cardiomyopathy is associated with excessive inflammatory response and apoptosis of cardiac myocytes during sepsis. MicroRNA-23b (miR-23b) is a multifunctional miRNA that is considered to regulate immunosuppression in sepsis. The aim of… read more here.
Keywords: sepsis; apoptosis; mir 23b; microrna 23b ... See more keywords
Circ_0020093 ameliorates IL-1β-induced apoptosis and extracellular matrix degradation of human chondrocytes by upregulating SPRY1 via targeting miR-23b
Sign Up to like & getrecommendations! Published in 2021 at "Molecular and Cellular Biochemistry"
DOI: 10.1007/s11010-021-04186-2
Abstract: Osteoarthritis (OA) is a chronic disease characterized by articular cartilage degeneration and uncontrolled chondrocyte apoptosis. At present, accumulating evidence introduces that circular RNA (circRNA) is involved in the development of OA. The aim of our… read more here.
Keywords: apoptosis; mir 23b; human chondrocytes; spry1 ... See more keywords
MircoRNA-23b-3p promotes the proliferation, migration, and epithelial-mesenchymal transition of lens epithelial cells by targeting Sprouty2.
Sign Up to like & getrecommendations! Published in 2019 at "Acta histochemica"
DOI: 10.1016/j.acthis.2019.05.007
Abstract: Cataract, opacification of the lens, is one of the most important reasons of visual impairment and blindness. Though microRNAs (miRNAs) have been demonstrated to play important roles in cataractogenesis, the underlying molecular mechanisms in this… read more here.
Keywords: proliferation migration; mesenchymal transition; mir 23b; migration ... See more keywords
MicroRNA-23b prevents aortic aneurysm formation by inhibiting smooth muscle cell phenotypic switching via FoxO4 suppression.
Sign Up to like & getrecommendations! Published in 2021 at "Life sciences"
DOI: 10.1016/j.lfs.2021.119092
Abstract: AIMS Phenotypic switching of vascular smooth muscle cells (VSMCs) is essential for the formation of abdominal aortic aneurysms (AAAs). MicroRNA-23b (miR-23b) has recently been shown to play a vital role in maintaining the VSMC contractile… read more here.
Keywords: mir 23b; formation; smooth muscle; mice ... See more keywords
LncRNA DLEU2 is activated by STAT1 and induces gastric cancer development via targeting miR-23b-3p/NOTCH2 axis and Notch signaling pathway.
Sign Up to like & getrecommendations! Published in 2021 at "Life sciences"
DOI: 10.1016/j.lfs.2021.119419
Abstract: INTRODUCTION Gastric cancer (GC) has severely affected the health of patients and caused high mortality around the world. Long non-coding RNAs (lncRNAs) have been validated to play significant roles in biological process of multiple cancers.… read more here.
Keywords: lncrna dleu2; gastric cancer; mir 23b; notch ... See more keywords
Chalcone suppresses tumor growth through NOX4-IRE1α sulfonation-RIDD-miR-23b axis.
Sign Up to like & getrecommendations! Published in 2021 at "Redox biology"
DOI: 10.1016/j.redox.2021.101853
Abstract: Chalcone is a polyphenolic compound found abundantly in natural plant components. They have been acclaimed as potential antitumor compounds in multiple tumor cells. However, not much attention has been paid to elucidate its antitumor mechanism… read more here.
Keywords: ridd; mir 23b; chalcone; sulfonation ... See more keywords
MicroRNA-23b-3p participates in steroid-induced osteonecrosis of the femoral head by suppressing ZNF667 expression
Sign Up to like & getrecommendations! Published in 2020 at "Steroids"
DOI: 10.1016/j.steroids.2020.108709
Abstract: BACKGROUND Clinical treatment with high-dose of steroid hormone causes steroid-induced osteonecrosis of the femoral head (SONFH), whereas the internal regulation mechanism remains elusive. Numerous studies have reported that microRNAs participated in the development of SONFH… read more here.
Keywords: znf667; mir 23b; steroid induced; expression ... See more keywords
miR-23b-3p inhibits chicken granulosa cell proliferation and steroid hormone synthesis via targeting GDF9.
Sign Up to like & getrecommendations! Published in 2021 at "Theriogenology"
DOI: 10.1016/j.theriogenology.2021.10.011
Abstract: MicroRNAs (miRNAs) are ∼22 nt RNAs that direct post-transcriptional repression of mRNA targets in diverse eukaryotic lineages. Granulosa cells (GCs) are the earliest differentiated follicular somatic cells. From the initiation of primordial follicles, their differentiation and… read more here.
Keywords: hormone synthesis; granulosa; granulosa cell; mir 23b ... See more keywords