Critical role of miR‐26a‐5p/Wnt5a signaling in gambogic acid‐induced inhibition of gastric cancer
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.22721
Abstract: Gastric cancer (GC) represents the fifth most human malignant disease and the third‐most common cause of cancer‐related death. Gambogic acid (GA) is a natural compound with a polyprenylated xanthone structure and possesses remarkable antitumor activity… read more here.
Keywords: mir 26a; gambogic acid; gastric cancer; wnt5a ... See more keywords
miR‐26a promoted endometrial epithelium cells (EECs) proliferation and induced stromal cells (ESCs) apoptosis via the PTEN‐PI3K/AKT pathway in dairy goats
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.26252
Abstract: Changes in endometrial cell morphology and function are absolutely necessary for successful embryo implantation. In this study, miR‐26a was widely expressed in dairy goats, and was found to be regulated by β‐estradiol (E2) and progesterone… read more here.
Keywords: dairy goats; endometrial epithelium; mir 26a; epithelium cells ... See more keywords
Silencing lncRNA Snhg6 mitigates bleomycin‐induced pulmonary fibrosis in mice via miR‐26a‐5p/TGF‐β1‐smads axis
Sign Up to like & getrecommendations! Published in 2022 at "Environmental Toxicology"
DOI: 10.1002/tox.23603
Abstract: Idiopathic pulmonary fibrosis (IPF) is an interstitial pulmonary disease with slow onset and high mortality. Epithelial–mesenchymal transition (EMT) is a significant condition for tissue fibrosis, and lncRNA‐Snhg6 (small nucleolar RNA host gene 6) is related… read more here.
Keywords: snhg6; pulmonary fibrosis; mir 26a; fibrosis ... See more keywords
MiR-26a Reduces Inflammatory Responses via Inhibition of PGE2 Production by Targeting COX-2
Sign Up to like & getrecommendations! Published in 2022 at "Inflammation"
DOI: 10.1007/s10753-022-01631-2
Abstract: MicroRNAs are small non-coding RNA regulatory molecules that play an important role in the development and function of immune cells. MicroRNA-26a (miR-26a) exhibits anti-inflammatory immune effects on immune cells. However, the exact mechanism by which… read more here.
Keywords: pge2; mir; 26a reduces; production ... See more keywords
MicroRNA-26a-5p alleviates neuronal apoptosis and brain injury in intracerebral hemorrhage by targeting RAN binding protein 9.
Sign Up to like & getrecommendations! Published in 2020 at "Acta histochemica"
DOI: 10.1016/j.acthis.2020.151571
Abstract: Emerging evidence has unraveled the important implications of microRNAs (miRNAs/miRs) in intracerebral hemorrhage (ICH). The aim of the present study was to assess the possible regulatory role of miR-26a-5p in ICH both in vivo and… read more here.
Keywords: apoptosis; mir 26a; intracerebral hemorrhage; neuronal apoptosis ... See more keywords
Stem cells from human exfoliated deciduous teeth transmit microRNA-26a to protect rats with experimental intracerebral hemorrhage from cerebral injury via suppressing CTGF
Sign Up to like & getrecommendations! Published in 2021 at "Brain Research Bulletin"
DOI: 10.1016/j.brainresbull.2020.12.006
Abstract: OBJECTIVE A large number of studies have shown that stem cells from human exfoliated deciduous teeth (SHED) has a protective effect on brain damage, but its specific mechanism is unclear. This research focused on the… read more here.
Keywords: mir 26a; expression; ctgf; injury ... See more keywords
MiRNA expression profiles reveal the involvement of miR-26a, miR-548l and miR-34a in hepatocellular carcinoma progression through regulation of ST3GAL5
Sign Up to like & getrecommendations! Published in 2017 at "Laboratory Investigation"
DOI: 10.1038/labinvest.2017.12
Abstract: MicroRNAs (miRNAs) have key roles in comprehensive physiological and pathological processes by targeting specific genes through translational repression. Identification of miRNAs related to metastasis enables us to obtain better insight into cancer development. In the… read more here.
Keywords: 26a mir; 548l mir; mir 26a; mir 34a ... See more keywords
Anti-leukemic activity of microRNA-26a in a chronic lymphocytic leukemia mouse model
Sign Up to like & getrecommendations! Published in 2017 at "Oncogene"
DOI: 10.1038/onc.2017.269
Abstract: Dysregulation of microRNAs (miRNAs) plays an important role in the pathogenesis of chronic lymphocytic leukemia (CLL). The Eμ-TCL1 transgenic mouse develops a form of leukemia that is similar to the aggressive type of human B-CLL,… read more here.
Keywords: lymphocytic leukemia; anti leukemic; mir 26a; model ... See more keywords
Novel prognostic marker LINC00205 promotes tumorigenesis and metastasis by competitively suppressing miRNA-26a in gastric cancer
Sign Up to like & getrecommendations! Published in 2022 at "Cell Death Discovery"
DOI: 10.1038/s41420-021-00802-8
Abstract: Rapid proliferation and metastasis of gastric cancer (GC) resulted in a poor prognosis in the clinic. Previous studies elucidated that long non-coding RNA (LncRNA) LINC00205 was upregulated in various tumors and participated in tumor progression.… read more here.
Keywords: linc00205; cell; gastric cancer; mir 26a ... See more keywords
Overexpression of preeclampsia induced microRNA-26a-5p leads to proteinuria in zebrafish
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-22070-w
Abstract: So far the pathomechanism of preeclampsia in pregnancy is focussed on increased circulating levels of soluble fms-like tyrosin kinase-1 (sFLT-1) that neutralizes glomerular VEGF-A expression and prevents its signaling at the glomerular endothelium. As a… read more here.
Keywords: microrna 26a; overexpression; overexpression preeclampsia; mir 26a ... See more keywords
Identification of housekeeping genes for microRNA expression analysis in kidney tissues of Pkd1 deficient mouse models
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-019-57112-4
Abstract: Polycystic kidney disease is a complex clinical entity which comprises a group of genetic diseases that leads to renal cyst development. We evaluated the most suitable housekeeping genes for microRNA expression by RT-qPCR analyses of… read more here.
Keywords: mir 26a; mir; housekeeping genes; kidney tissues ... See more keywords