Plasma Extracellular Vesicle‐Derived miR‐296‐5p is a Maturation‐Dependent Rejuvenation Factor that Downregulates Inflammation and Improves Survival after Sepsis
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Extracellular Vesicles"
DOI: 10.1002/jev2.70065
Abstract: ABSTRACT There is a progressive decline in physiological function with age, and aging is associated with increased susceptibility to injury and infection. However, several reports have indicated that the agility of youth is characterized by… read more here.
Keywords: age; effect; mir 296; maturation dependent ... See more keywords
Downregulation of miR-296-3p by highly pathogenic porcine reproductive and respiratory syndrome virus activates the IRF1/TNF-α signaling axis in porcine alveolar macrophages
Sign Up to like & getrecommendations! Published in 2021 at "Archives of Virology"
DOI: 10.1007/s00705-020-04921-y
Abstract: Porcine reproductive and respiratory syndrome virus (PRRSV, species Betaarterivirus suid 1 or 2 ) is a major pathogen affecting pigs on farms throughout the world. miR-296-3p is a multifunctional microRNA involved in the regulation of… read more here.
Keywords: tnf; highly pathogenic; infection; porcine ... See more keywords
The Long Noncoding RNA CAREL Controls Cardiac Regeneration.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the American College of Cardiology"
DOI: 10.1016/j.jacc.2018.04.085
Abstract: BACKGROUND Adult mammalian heart loses regeneration ability following ischemic injury due to the loss of cardiomyocyte mitosis. However, the molecular mechanisms underlying the post-mitotic nature of cardiomyocytes remain largely unknown. OBJECTIVES The purpose of this… read more here.
Keywords: heart; cardiac regeneration; regeneration; mir 296 ... See more keywords
ELF1-activated FOXD3-AS1 promotes the migration, invasion and EMT of osteosarcoma cells via sponging miR-296-5p to upregulate ZCCHC3
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Bone Oncology"
DOI: 10.1016/j.jbo.2020.100335
Abstract: Highlights • FOXD3-AS1 downregulation inhibits cell migration, invasion and EMT in osteosarcoma.• Overexpression of miR-296-5p hinders the malignant behaviors of osteosarcoma cells.• FOXD3-AS1 sponges miR-296-5p to elevate ZCCHC3 to facilitate malignancy in osteosarcoma.• ELF1 activates… read more here.
Keywords: emt osteosarcoma; invasion emt; mir 296; osteosarcoma cells ... See more keywords
Circ_0076305 regulates cisplatin resistance of non-small cell lung cancer via positively modulating STAT3 by sponging miR-296-5p.
Sign Up to like & getrecommendations! Published in 2019 at "Life sciences"
DOI: 10.1016/j.lfs.2019.116984
Abstract: AIMS Circular RNAs (circRNAs) acted as key regulators in the development of various human tumors. Our present study aimed to investigate the role and molecular mechanism of circ_0076305 in regulating cisplatin (DDP) resistance of non-small… read more here.
Keywords: mir 296; ddp resistance; stat3; circ 0076305 ... See more keywords
RETRACTED ARTICLE: Inhibition of miR-296-5p protects the heart from cardiac hypertrophy by targeting CACNG6
Sign Up to like & getrecommendations! Published in 2019 at "Gene Therapy"
DOI: 10.1038/s41434-019-0109-0
Abstract: Heart often undergoes mal-remodeling and hypertrophic growth in response to pathological stress. MiRNAs can regulate the cardiac function and participate in the regulation of cardiac hypertrophy. The present study aims at identifying the role of… read more here.
Keywords: mir 296; cardiac hypertrophy; inhibition mir; heart ... See more keywords
MiRNA-296-5p promotes the sensitivity of nasopharyngeal carcinoma cells to cisplatin via targeted inhibition of STAT3/KLF4 signaling axis
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DOI: 10.1038/s41598-024-55123-4
Abstract: Improving drug sensitivity is an important strategy in chemotherapy of cancer and accumulating evidence indicates that miRNAs are involved in the regulation of drug sensitivity, but the specific mechanism is still unclear. Our previous study… read more here.
Keywords: npc cells; mir 296; nasopharyngeal carcinoma; sensitivity ... See more keywords
Hsa_Circ_0005044 Promotes Osteo/Odontogenic Differentiation of Dental Pulp Stem Cell Via Modulating miR-296-3p/FOSL1.
Sign Up to like & getrecommendations! Published in 2022 at "DNA and cell biology"
DOI: 10.1089/dna.2022.0394
Abstract: Circular RNAs (circRNAs) are a form of RNAs that lack coding potential. The role of such circRNAs in dental pulp stem cell (DPSC) osteo/odontogenic differentiation remains to be determined. In this study, circRNA expression profiles… read more here.
Keywords: fosl1; mir 296; circ 0005044; differentiation ... See more keywords
Retracted: Silencing of Exosomal miR‐296‐5p Derived from Endothelial Progenitor Cells Enhances Thrombolysis and Recanalization in Deep Vein Thrombosis
Sign Up to like & getrecommendations! Published in 2020 at "Clinical and Translational Science"
DOI: 10.1111/cts.12799
Abstract: Retraction: Wang, J., Yang, Z., Liu, S., Zhang, L., & Zhao, Y. Silencing of Exosomal miR‐296‐5p Derived from Endothelial Progenitor Cells Enhances Thrombolysis and Recanalization in Deep Vein Thrombosis, Clin. Trans. Sci. https://ascpt.onlinelibrary.wiley.com/doi/full/10.1111/cts.12799 read more here.
Keywords: mir 296; endothelial progenitor; derived endothelial; 296 derived ... See more keywords
Long Noncoding XLOC_006390 Regulates the Proliferation and Metastasis of Human Colorectal Cancer via miR-296/ONECUT2 Axis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Oncology"
DOI: 10.1155/2022/4897201
Abstract: Long noncoding RNA (LncRNA) XLOC_006390 has been shown to be dysregulated in cancer tissues and regulates cancer growth and development. Nonetheless, the molecular role of lncRNA-XLOC_006390 in colorectal cancer via modulation of miR-296/ONECUT2 axis is… read more here.
Keywords: xloc 006390; lncrna xloc; colorectal cancer; cancer ... See more keywords
circ_000166/miR-296 Aggravates the Process of Diabetic Renal Fibrosis by Regulating the SGLT2 Signaling Pathway in Renal Tubular Epithelial Cells
Sign Up to like & getrecommendations! Published in 2022 at "Disease Markers"
DOI: 10.1155/2022/6103086
Abstract: Diabetic renal fibrosis is a common cause of end-stage renal disease, and the circRNA-miRNA-mRNA network may play an important role in the progression of diabetic nephropathy- (DN-) induced renal fibrosis. In this study, the role… read more here.
Keywords: renal fibrosis; circ 000166; 000166 mir; fibrosis ... See more keywords