Role of XIST/miR‐29a/LIN28A pathway in denatured dermis and human skin fibroblasts (HSFs) after thermal injury
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.26307
Abstract: Denatured dermis is a part of the dermis in deep burn wound and has the ability to restore normal morphology and function. In our previous study, we revealed that miR‐29a downregulation in denatured dermis may… read more here.
Keywords: mir 29a; denatured dermis; 29a lin28a; human skin ... See more keywords
Significance of serum miR‐29a in the occurrence and progression of diabetic nephropathy: A cross‐sectional study
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24210
Abstract: Diabetic nephropathy (DN), a common microvascular complication of type 2 diabetes mellitus (T2DM), is an important factor causing chronic kidney disease. However, the relationship between miR‐29a and DN remains unknown. Therefore, a cross‐sectional study was… read more here.
Keywords: cross sectional; diabetic nephropathy; mir 29a; serum mir ... See more keywords
Elevated miR-29a Contributes to Axonal Outgrowth and Neurological Recovery After Intracerebral Hemorrhage via Targeting PTEN/PI3K/Akt Pathway.
Sign Up to like & getrecommendations! Published in 2020 at "Cellular and molecular neurobiology"
DOI: 10.1007/s10571-020-00945-9
Abstract: Spontaneous intracerebral hemorrhage (ICH) is a clinical challenge with high disability and lacks an effective treatment. miR-29a strongly expressed in the brain has been implicated in various neurological disorders. In this study, we investigated the… read more here.
Keywords: outgrowth neurological; mir 29a; outgrowth; pi3k akt ... See more keywords
Lentivirus-Mediated Overexpression of miR-29a Promotes Axonal Regeneration and Functional Recovery in Experimental Spinal Cord Injury via PI3K/Akt/mTOR Pathway
Sign Up to like & getrecommendations! Published in 2018 at "Neurochemical Research"
DOI: 10.1007/s11064-018-2625-5
Abstract: MicroRNAs as a novel class of endogenous small non-coding RNAs, modulate negative gene expression at the post-transcriptional level. Our previous work has demonstrated that miR-29a reduces PTEN expression by directly targeting the 3′-UTRs (untranslated regions)… read more here.
Keywords: recovery; axonal regeneration; expression; mir 29a ... See more keywords
Klotho Ameliorates Cellular Inflammation via Suppression of Cytokine Release and Upregulation of miR-29a in the PBMCs of Diagnosed Alzheimer’s Disease Patients
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Molecular Neuroscience"
DOI: 10.1007/s12031-019-01345-5
Abstract: Alzheimer’s disease (AD) is the most common neurodegenerative disorder characterized by neural inflammation and oxidative stress. In the current study, the protective effects of klotho and linagliptin treatment on human peripheral blood mononuclear cells (PBMCs)… read more here.
Keywords: mir 29a; alzheimer disease; upregulation mir; inflammation ... See more keywords
COL4A1, negatively regulated by XPD and miR-29a-3p, promotes cell proliferation, migration, invasion and epithelial–mesenchymal transition in liver cancer cells
Sign Up to like & getrecommendations! Published in 2021 at "Clinical and Translational Oncology"
DOI: 10.1007/s12094-021-02611-y
Abstract: Collagen type IV alpha 1 (COL4A1) exerts tumor-promoting functions in several tumors. However, its role in liver cancer remains not fully understood. Hence, this study aims to investigate the role of COL4A1 in regulating liver… read more here.
Keywords: col4a1; proliferation migration; mir 29a; xpd ... See more keywords
miR-29a suppresses growth and migration of hepatocellular carcinoma by regulating CLDN1.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.03.110
Abstract: CLDN1 (claudin1) is essential for intercellular junctions and has been reported to be involving in cell migration and metastasis, making it as an oncogene in various cancer types. However, the biological function roles and regulatory… read more here.
Keywords: hepatocellular carcinoma; growth migration; cldn1; mir 29a ... See more keywords
Yunpi Heluo decoction attenuates insulin resistance by regulating liver miR-29a-3p in Zucker diabetic fatty rats.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2019.111966
Abstract: BACKGROUND AND OBJECTIVE Yunpiheluo (YPHL) decoction is a Chinese herbal formula with unique advantages for the treatment of type 2 diabetes mellitus (T2DM). The aim of the present study was to investigate changes in miRNA… read more here.
Keywords: zucker diabetic; diabetic fatty; decoction; mir 29a ... See more keywords
Curcumin inhibits proliferation and soluble collagen synthesis of NIH/3T3 cell line by modulation of miR-29a and via ERK1/2 and β-catenin pathways.
Sign Up to like & getrecommendations! Published in 2019 at "Molecular immunology"
DOI: 10.1016/j.molimm.2019.10.018
Abstract: BACKGROUND Scars affects the appearance and results in tissue damage. In this research, we preliminarily studied the function and mechanism of curcumin (CUR) on cell proliferation and soluble collagen synthesis in NIH-3T3 cells. METHODS CCK-8… read more here.
Keywords: collagen; mir 29a; proliferation; soluble collagen ... See more keywords
Long noncoding TUG1 promotes angiogenesis of HUVECs in PE via regulating the miR-29a-3p/VEGFA and Ang2/Tie2 pathways.
Sign Up to like & getrecommendations! Published in 2021 at "Microvascular research"
DOI: 10.1016/j.mvr.2021.104231
Abstract: BACKGROUND Preeclampsia (PE) is a pregnancy-specific disease that is associated with oxidative stress-induced endothelial dysfunction. Long noncoding RNAs (lncRNAs) are related to PE progression. The purpose is to study whether lncRNA taurine-upregulated gene 1 (TUG1)… read more here.
Keywords: tug1; ang2 tie2; mir 29a; vegfa ang2 ... See more keywords
Epigenetic regulation of miR-29a/miR-30c/DNMT3A axis controls SOD2 and mitochondrial oxidative stress in human mesenchymal stem cells
Sign Up to like & getrecommendations! Published in 2020 at "Redox Biology"
DOI: 10.1016/j.redox.2020.101716
Abstract: The use of human mesenchymal stem cells (hMSCs) in clinical applications requires large-scale cell expansion prior to administration. However, the prolonged culture of hMSCs results in cellular senescence, impairing their proliferation and therapeutic potentials. To… read more here.
Keywords: hmscs; mir 29a; mir; senescence ... See more keywords