Platelet lysate induces chondrogenic differentiation of umbilical cord‐derived mesenchymal stem cells by regulating the lncRNA H19/miR‐29b‐3p/SOX9 axis
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DOI: 10.1002/2211-5463.13002
Abstract: Platelet lysate (PL) has been shown to induce chondrogenic differentiation of human umbilical cord‐derived mesenchymal stem cells (hUCMSCs). However, the underlying mechanism is still not clear. The aim of this study was to investigate whether… read more here.
Keywords: h19 mir; chondrogenic differentiation; sox9; mir 29b ... See more keywords
MiR-29b mimics promotes cell apoptosis of smooth muscle cells via targeting on MMP-2
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DOI: 10.1007/s10616-017-0150-z
Abstract: The phenotypic transformation and dysfunctions of vascular smooth muscle cells (SMCs) such as abnormality proliferation and apoptosis are key pathological basis of atherosclerosis. The recent study aimed to detect the role of miR-29b in phenotypic… read more here.
Keywords: viability; cell apoptosis; mmp; mir 29b ... See more keywords
Titanium dioxide nanoparticles induced the apoptosis of RAW264.7 macrophages through miR-29b-3p/NFAT5 pathway
Sign Up to like & getrecommendations! Published in 2020 at "Environmental Science and Pollution Research"
DOI: 10.1007/s11356-020-08952-5
Abstract: Titanium dioxide nanoparticles (TiO 2 NPs) are widely found in consumer and industrial products, contributing to their prevalent presence in our surroundings. In this study, several miRNAs in the immuno-related pathways were found to be… read more here.
Keywords: apoptosis; titanium dioxide; 29b nfat5; mir 29b ... See more keywords
HDAC4 Knockdown Induces Preeclampsia Cell Autophagy and Apoptosis by miR-29b
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DOI: 10.1007/s43032-020-00286-4
Abstract: Preeclampsia (PE) is one of the main causes of maternal death and perinatal morbidity and mortality. Considering that histone deacetylase 4 (HDAC4) activity could relate to trophoblast cell motility and be antagonized by miR-29b, the… read more here.
Keywords: autophagy apoptosis; hdac4; trophoblast; mir 29b ... See more keywords
Age-associated changes in microRNAs affect the differentiation potential of human mesenchymal stem cells: Novel role of miR-29b-1-5p expression.
Sign Up to like & getrecommendations! Published in 2021 at "Bone"
DOI: 10.1016/j.bone.2021.116154
Abstract: Age-associated osteoporosis is widely accepted as involving the disruption of osteogenic stem cell populations and their functioning. Maintenance of the local bone marrow (BM) microenvironment is critical for regulating proliferation and differentiation of the multipotent… read more here.
Keywords: age; bone; expression; age associated ... See more keywords
Expression Analysis of miR‐29b in Malignant and Benign Breast Tumors: A Promising Prognostic Biomarker for Invasive Ductal Carcinoma With a Possible Histotype‐Related Expression Status
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DOI: 10.1016/j.clbc.2017.11.007
Abstract: &NA; The transcript levels of miR‐29b, which has been claimed to be involved in breast cancer molecular pathology, were evaluated with regard to their clinical utility by analyzing miR‐29b expression in 177 breast tissue samples… read more here.
Keywords: breast; invasive ductal; ductal carcinoma; expression ... See more keywords
The lncRNA NEAT1/miR-29b/Atg9a axis regulates IGFBPrP1-induced autophagy and activation of mouse hepatic stellate cells.
Sign Up to like & getrecommendations! Published in 2019 at "Life sciences"
DOI: 10.1016/j.lfs.2019.116902
Abstract: AIMS Insulin-like growth factor binding protein-related protein 1 (IGFBPrP1) promotes hepatic stellate cell (HSC) autophagy and activation. However, the underlying mechanism remains unknown. Noncoding RNAs (ncRNAs) including long noncoding RNAs (lncRNAs) and microRNAs (miRNAs), have… read more here.
Keywords: 29b atg9a; autophagy activation; neat1 mir; mir 29b ... See more keywords
Mir-29b mediates the regulation of Nrf2 on airway epithelial remodeling and Th1/Th2 differentiation in COPD rats
Sign Up to like & getrecommendations! Published in 2019 at "Saudi Journal of Biological Sciences"
DOI: 10.1016/j.sjbs.2019.07.011
Abstract: COPD, or Chronic obstructive pulmonary disease, is an inflammation-related disease and lead to cachexia and muscle wasting. Altered nuclear factor erythroid 2-related factor 2 (Nrf2) expression is found in patients of COPD because it is… read more here.
Keywords: copd; regulation nrf2; expression; th1 th2 ... See more keywords
miR-29b contributes to multiple types of muscle atrophy
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DOI: 10.1038/ncomms15201
Abstract: A number of microRNAs (miRNAs, miRs) have been shown to play a role in skeletal muscle atrophy, but their role is not completely understood. Here we show that miR-29b promotes skeletal muscle atrophy in response… read more here.
Keywords: 29b contributes; contributes multiple; muscle atrophy; mir 29b ... See more keywords
Rapamycin-upregulated miR-29b promotes mTORC1-hyperactive cell growth in TSC2-deficient cells by downregulating tumor suppressor retinoic acid receptor β (RARβ)
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DOI: 10.1038/s41388-019-0957-5
Abstract: miR-29b has been identified as a rapamycin-induced microRNA (miRNA) in Tsc2-deficient, mTORC1-hyperactive cells. The biological significance of this induction of miR-29b is unknown. We have found that miR-29b acts as an oncogenic miRNA in Tsc2-deficient… read more here.
Keywords: rar; deficient cells; mir 29b; cell ... See more keywords
Human umbilical cord mesenchymal stem cells-derived extracellular vesicles facilitate the repair of spinal cord injury via the miR-29b-3p/PTEN/Akt/mTOR axis
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DOI: 10.1038/s41420-021-00572-3
Abstract: Spinal cord injury (SCI) is a salient traumatic disease that often leads to permanent disability, and motor and sensory impairments. Human umbilical cord mesenchymal stem cells (HucMSCs) have a wide application prospect in the treatment… read more here.
Keywords: hucmscs evs; sci rats; cord; mir 29b ... See more keywords