Verification of candidate microRNA markers for parathyroid carcinoma
Sign Up to like & getrecommendations! Published in 2018 at "Endocrine"
DOI: 10.1007/s12020-018-1551-2
Abstract: PurposeParathyroid carcinoma (PCa) is a rare endocrine malignancy with poor prognosis and is often difficult to accurately diagnose both before and after surgery. Dysregulated microRNA (miRNA) levels have been identified in PCa using a limited… read more here.
Keywords: mir 139; mir 222; mir 30b; mir ... See more keywords
miR-30b-5p releases HMGB1 via UBE2D2/KAT2B/HMGB1 pathway to promote pro-inflammatory polarization and recruitment of macrophages.
Sign Up to like & getrecommendations! Published in 2021 at "Atherosclerosis"
DOI: 10.1016/j.atherosclerosis.2021.02.016
Abstract: BACKGROUND AND AIMS Oxidized low-density lipoprotein (ox-LDL) is a key risk factor for atherosclerosis, but there are few reports on ox-LDL-mediated inflammation after injury. In this study, we investigated the effects of ox-LDL on endothelial… read more here.
Keywords: pro inflammatory; mir 30b; polarization recruitment;
Brown adipose tissue transplantation ameliorates diabetic nephropathy through the miR-30b pathway by targeting Runx1.
Sign Up to like & getrecommendations! Published in 2021 at "Metabolism: clinical and experimental"
DOI: 10.1016/j.metabol.2021.154916
Abstract: OBJECTIVE Adipose tissue is a major source of circulating microRNAs (miRNAs) that can regulate target genes in distant organs. However, the role of brown adipose tissue (BAT) in diabetic kidney disease (DKD) is still unknown.… read more here.
Keywords: adipose tissue; runx1; bat; mir 30b ... See more keywords
miR-30-5p-mediated ferroptosis of trophoblasts is implicated in the pathogenesis of preeclampsia
Sign Up to like & getrecommendations! Published in 2020 at "Redox Biology"
DOI: 10.1016/j.redox.2019.101402
Abstract: Oxidative stress is a major cause of adverse outcomes in preeclampsia (PE). Ferroptosis, i.e. programmed cell death from iron-dependent lipid peroxidation, likely mediates PE pathogenesis. We evaluated specific markers for ferroptosis in normal and PE… read more here.
Keywords: mir 30b; pathogenesis; ferroptosis; mediated ferroptosis ... See more keywords
Long non-coding RNA HNF1A-AS1 induces 5-FU resistance of gastric cancer through miR-30b-5p/EIF5A2 pathway
Sign Up to like & getrecommendations! Published in 2022 at "Translational Oncology"
DOI: 10.1016/j.tranon.2022.101351
Abstract: Highlights • HNF1A-AS1 promotes 5-FU resistance in gastric cancer cells.• HNF1A-AS1 regulates EIF5A2 expression through sponging miR-30b-5p.• HNF1A-AS1 promotes EMT process and 5-FU resistance through miR-30b-5p/EIF5A2 pathway.• HNF1A-AS1 promotes 5-FU resistance in gastric cancer in… read more here.
Keywords: gastric cancer; mir 30b; resistance gastric; hnf1a as1 ... See more keywords
Decreased lipid metabolism but increased FA biosynthesis are coupled with changes in liver microRNAs in obese subjects with NAFLD
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Obesity"
DOI: 10.1038/ijo.2017.21
Abstract: Background/Objective:Many controversies regarding the association of liver miRNAs with obesity and nonalcoholic fatty liver diseases (NAFLD) call for additional validations. This study sought to investigate variations in genes and hepatic miRNAs in a sample of… read more here.
Keywords: mir 139; biosynthesis; mir 30b; metabolism ... See more keywords
The role of miR-26a and miR-30b in HER2+ breast cancer trastuzumab resistance and regulation of the CCNE2 gene
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep41309
Abstract: A subset of HER2+ breast cancer patients manifest clinical resistance to trastuzumab. Recently, miR-26a and miR-30b have been identified as trastuzumab response regulators, and their target gene CCNE2 seems to play an important role in… read more here.
Keywords: 26a mir; mir 30b; mir 26a; resistance ... See more keywords
Silencing of Long Noncoding RNA TUG1 Ameliorates Atherosclerosis-Induced Myocardial Injury by Upregulating microRNA-30b-3p and Downregulating Brd4
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cardiovascular Pharmacology"
DOI: 10.1097/fjc.0000000000001367
Abstract: Supplemental Digital Content is Available in the Text. Abstract: Long noncoding RNAs and microRNAs (miRNAs) are emerging biomarkers involved in human diseases, and we focused on the roles of long noncoding RNA taurine upregulated gene… read more here.
Keywords: myocardial injury; tug1; atherosclerosis induced; induced myocardial ... See more keywords
Propofol Upregulates MicroRNA-30b to Inhibit Excessive Autophagy and Apoptosis and Attenuates Ischemia/Reperfusion Injury In Vitro and in Patients
Sign Up to like & getrecommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2022/2109891
Abstract: Evidence reveals that propofol protects cells via suppressing excessive autophagy induced by hypoxia/reoxygenation (H/R). Previously, we found in a genome-wide microRNA profile analysis that several autophagy-related microRNAs were significantly altered during the process of H/R… read more here.
Keywords: excessive autophagy; mir 30b; propofol upregulates; microrna 30b ... See more keywords
Downregulation of hsa-miR-30b-3p Inhibits the Oncogenicity of Lung Adenocarcinoma by Targeting the METTL7B Gene
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Oncology"
DOI: 10.1155/2022/6883140
Abstract: Objective Lung adenocarcinoma (LUAD) is one of the malignant tumors with the highest morbidity and mortality rates worldwide. Although surgery-based combination therapy can greatly improve the prognosis of LUAD patients, the overall outcome is still… read more here.
Keywords: luad patients; lung adenocarcinoma; mettl7b gene; lung ... See more keywords
Chi-miR-30b-5p inhibits dermal papilla cells proliferation by targeting CaMKIIδ gene in cashmere goat
Sign Up to like & getrecommendations! Published in 2020 at "BMC Genomics"
DOI: 10.1186/s12864-020-06799-1
Abstract: During goat embryonic morphogenesis and postnatal initiation of hair follicle (HF) regeneration, dermal papilla (DP) cells play a vital role in hair formation. Growing evidence shows that microRNAs (miRNAs) participate in HF development and DP… read more here.
Keywords: chi mir; mir 30b; proliferation; gene ... See more keywords