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   Articles with "mir 30b" as a keyword



Label‐Free Electrochemical Microfluidic Sensing Platform for the Detection of miR‐30b from Milk Samples

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recommendations! Published in 2025 at "Electroanalysis"

DOI: 10.1002/elan.70066

Abstract: Circulating microRNAs (miRNAs) in biological fluids are small non‐coding RNAs identified as promising biomarkers. They are particularly abundant in milk, a fluid easily accessible without invasive techniques. However, detection methods are currently performed by specialized… read more here.

Keywords: detection; detection mir; mir 30b; platform detection ... See more keywords

Up‐Regulation of miR‐30b‐3p by Krüppel‐Like Factor 5 Induces the Apoptosis and Oxidative Stress in Sow Ovarian Granulosa Cells Through Inhibiting SMAD3 and SOD2

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recommendations! Published in 2025 at "Journal of Cellular Physiology"

DOI: 10.1002/jcp.70103

Abstract: MicroRNAs (miRNAs) have been demonstrated to be involved in various cellular biological processes. However, their impacts on apoptosis and oxidative stress in ovarian granulosa cells (GC) remain largely unknown. Here, we identified that miR‐30b was… read more here.

Keywords: sow; oxidative stress; mir 30b; gcs ... See more keywords
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Verification of candidate microRNA markers for parathyroid carcinoma

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recommendations! Published in 2018 at "Endocrine"

DOI: 10.1007/s12020-018-1551-2

Abstract: PurposeParathyroid carcinoma (PCa) is a rare endocrine malignancy with poor prognosis and is often difficult to accurately diagnose both before and after surgery. Dysregulated microRNA (miRNA) levels have been identified in PCa using a limited… read more here.

Keywords: mir 139; mir 222; mir 30b; mir ... See more keywords
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miR-30b-5p releases HMGB1 via UBE2D2/KAT2B/HMGB1 pathway to promote pro-inflammatory polarization and recruitment of macrophages.

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recommendations! Published in 2021 at "Atherosclerosis"

DOI: 10.1016/j.atherosclerosis.2021.02.016

Abstract: BACKGROUND AND AIMS Oxidized low-density lipoprotein (ox-LDL) is a key risk factor for atherosclerosis, but there are few reports on ox-LDL-mediated inflammation after injury. In this study, we investigated the effects of ox-LDL on endothelial… read more here.

Keywords: pro inflammatory; mir 30b; polarization recruitment;
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Brown adipose tissue transplantation ameliorates diabetic nephropathy through the miR-30b pathway by targeting Runx1.

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recommendations! Published in 2021 at "Metabolism: clinical and experimental"

DOI: 10.1016/j.metabol.2021.154916

Abstract: OBJECTIVE Adipose tissue is a major source of circulating microRNAs (miRNAs) that can regulate target genes in distant organs. However, the role of brown adipose tissue (BAT) in diabetic kidney disease (DKD) is still unknown.… read more here.

Keywords: adipose tissue; runx1; bat; mir 30b ... See more keywords
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miR-30-5p-mediated ferroptosis of trophoblasts is implicated in the pathogenesis of preeclampsia

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recommendations! Published in 2020 at "Redox Biology"

DOI: 10.1016/j.redox.2019.101402

Abstract: Oxidative stress is a major cause of adverse outcomes in preeclampsia (PE). Ferroptosis, i.e. programmed cell death from iron-dependent lipid peroxidation, likely mediates PE pathogenesis. We evaluated specific markers for ferroptosis in normal and PE… read more here.

Keywords: mir 30b; pathogenesis; ferroptosis; mediated ferroptosis ... See more keywords

Long non-coding RNA HNF1A-AS1 induces 5-FU resistance of gastric cancer through miR-30b-5p/EIF5A2 pathway

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recommendations! Published in 2022 at "Translational Oncology"

DOI: 10.1016/j.tranon.2022.101351

Abstract: Highlights • HNF1A-AS1 promotes 5-FU resistance in gastric cancer cells.• HNF1A-AS1 regulates EIF5A2 expression through sponging miR-30b-5p.• HNF1A-AS1 promotes EMT process and 5-FU resistance through miR-30b-5p/EIF5A2 pathway.• HNF1A-AS1 promotes 5-FU resistance in gastric cancer in… read more here.

Keywords: gastric cancer; mir 30b; resistance gastric; hnf1a as1 ... See more keywords

Decreased lipid metabolism but increased FA biosynthesis are coupled with changes in liver microRNAs in obese subjects with NAFLD

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recommendations! Published in 2017 at "International Journal of Obesity"

DOI: 10.1038/ijo.2017.21

Abstract: Background/Objective:Many controversies regarding the association of liver miRNAs with obesity and nonalcoholic fatty liver diseases (NAFLD) call for additional validations. This study sought to investigate variations in genes and hepatic miRNAs in a sample of… read more here.

Keywords: mir 139; biosynthesis; mir 30b; metabolism ... See more keywords

LncRNA BRE-AS1 regulates the JAK2/STAT3-mediated inflammatory activation via the miR-30b-5p/SOC3 axis in THP-1 cells

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recommendations! Published in 2024 at "Scientific Reports"

DOI: 10.1038/s41598-024-77265-1

Abstract: Long non-coding RNAs (lncRNAs) have emerged as pivotal regulators in numerous biological processes, including macrophage-mediated inflammatory responses, which play a critical role in the progress of diverse diseases. This study focuses on the regulatory function… read more here.

Keywords: lncrna bre; mir 30b; jak2 stat3; bre as1 ... See more keywords

The role of miR-26a and miR-30b in HER2+ breast cancer trastuzumab resistance and regulation of the CCNE2 gene

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recommendations! Published in 2017 at "Scientific Reports"

DOI: 10.1038/srep41309

Abstract: A subset of HER2+ breast cancer patients manifest clinical resistance to trastuzumab. Recently, miR-26a and miR-30b have been identified as trastuzumab response regulators, and their target gene CCNE2 seems to play an important role in… read more here.

Keywords: 26a mir; mir 30b; mir 26a; resistance ... See more keywords

#899 The effect of exercise training on microRNAs in patients undergoing hemodialysis

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recommendations! Published in 2024 at "Nephrology Dialysis Transplantation"

DOI: 10.1093/ndt/gfae069.1625

Abstract: Physical inactivity is a risk factor for mortality and morbidity in patients undergoing hemodialysis (HD). Therefore, physical exercise (PE) is recommended as part of the management of HD patients. Although the benefits of PE for… read more here.

Keywords: patients undergoing; mir 30b; exercise training; undergoing hemodialysis ... See more keywords